Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancer

por Hollis, Robert L, Churchman, Michael, Gourley, Charlie
Publicado 2017

Ovarian carcinosarcoma is a distinct form of ovarian cancer with poorer survival compared to tubo-ovarian high-grade serous carcinoma

por Hollis, Robert L., Croy, Ian, Churchman, Michael, Bartos, Clare, Rye, Tzyvia, Gourley, Charlie, Herrington, C. Simon
Publicado 2022

Analysis of variants in DNA damage signalling genes in bladder cancer

por Choudhury, Ananya, Elliott, Faye, Iles, Mark M, Churchman, Michael, Bristow, Robert G, Bishop, D Timothy, Kiltie, Anne E
Publicado 2008

Hormone receptor expression patterns define clinically meaningful subgroups of endometrioid ovarian carcinoma

por Hollis, Robert L., Stanley, Barbara, Iida, Yasushi, Thomson, John, Churchman, Michael, Rye, Tzyvia, Mackean, Melanie, Nussey, Fiona, Gourley, Charlie, Herrington, C. Simon
Publicado 2019

Identifying and Overcoming Mechanisms of PARP Inhibitor Resistance in Homologous Recombination Repair-Deficient and Repair-Proficient High Grade Serous Ovarian Cancer Cells

por Gomez, Miriam K., Illuzzi, Giuditta, Colomer, Carlota, Churchman, Michael, Hollis, Robert L., O’Connor, Mark J., Gourley, Charlie, Leo, Elisabetta, Melton, David W.
Publicado 2020

Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations

por Hollis, Robert L., Meynert, Alison M., Churchman, Michael, Rye, Tzyvia, Mackean, Melanie, Nussey, Fiona, Arends, Mark J., Sims, Andrew H., Semple, Colin A., Herrington, C. Simon, Gourley, Charlie
Publicado 2018

Clinical and molecular characterization of ovarian carcinoma displaying isolated lymph node relapse

por Hollis, Robert L., Carmichael, Juliet, Meynert, Alison M., Churchman, Michael, Hallas-Potts, Amelia, Rye, Tzyvia, MacKean, Melanie, Nussey, Fiona, Semple, Colin A., Herrington, C. Simon, Gourley, Charlie
Publicado 2019

Clinicopathological Determinants of Recurrence Risk and Survival in Mucinous Ovarian Carcinoma

por Hollis, Robert L., Stillie, Lorna J., Hopkins, Samantha, Bartos, Clare, Churchman, Michael, Rye, Tzyvia, Nussey, Fiona, Fegan, Scott, Nirsimloo, Rachel, Inman, Gareth J., Herrington, C. Simon, Gourley, Charlie
Publicado 2021

Integrated molecular characterisation of endometrioid ovarian carcinoma identifies opportunities for stratification

por Hollis, Robert L., Stanley, Barbara, Thomson, John P., Churchman, Michael, Croy, Ian, Rye, Tzyvia, Bartos, Clare, Nussey, Fiona, Mackean, Melanie, Meynert, Alison M., Semple, Colin A., Gourley, Charlie, Herrington, C. Simon
Publicado 2021

Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome

por Hollis, Robert L., Thomson, John P., Stanley, Barbara, Churchman, Michael, Meynert, Alison M., Rye, Tzyvia, Bartos, Clare, Iida, Yasushi, Croy, Ian, Mackean, Melanie, Nussey, Fiona, Okamoto, Aikou, Semple, Colin A., Gourley, Charlie, Herrington, C. Simon
Publicado 2020

In vitro functional effects of XPC gene rare variants from bladder cancer patients

por Qiao, Boling, Ansari, Abdul-Haq, Scott, Gina B., Sak, Sei C., Chambers, Philip A., Elliott, Faye, Teo, Mark T.W., Bentley, Johanne, Churchman, Michael, Hall, Janet, Taylor, Claire F., Bishop, Timothy D., Knowles, Margaret A., Kiltie, Anne E.
Publicado 2011

High EMSY expression defines a BRCA‐like subgroup of high‐grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum

por Hollis, Robert L., Churchman, Michael, Michie, Caroline O., Rye, Tzyvia, Knight, Laura, McCavigan, Andrena, Perren, Timothy, Williams, Alistair R. W., McCluggage, W. Glenn, Kaplan, Richard S., Jayson, Gordon C., Oza, Amit, Harkin, D. Paul, Herrington, C. Simon, Kennedy, Richard, Gourley, Charlie
Publicado 2019

Distinct histopathological features are associated with molecular subtypes and outcome in low grade serous ovarian carcinoma

por Hollis, Robert L., Thomson, John P., van Baal, Juliette, Ilenkovan, Narthana, Churchman, Michael, van de Vijver, Koen, Dijk, Frederike, Meynert, Alison M., Bartos, Clare, Rye, Tzyvia, Croy, Ian, Diana, Patricia, van Gent, Mignon, Creedon, Helen, Nirsimloo, Rachel, Lok, Christianne, Gourley, Charlie, Herrington, C. Simon
Publicado 2023

Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification

por Hollis, Robert L., Meynert, Alison M., Michie, Caroline O., Rye, Tzyvia, Churchman, Michael, Hallas-Potts, Amelia, Croy, Ian, McCluggage, W. Glenn, Williams, Alistair R.W., Bartos, Clare, Iida, Yasushi, Okamoto, Aikou, Dougherty, Brian, Barrett, J. Carl, March, Ruth, Matakidou, Athena, Roxburgh, Patricia, Semple, Colin A., Harkin, D. Paul, Kennedy, Richard, Herrington, C. Simon, Gourley, Charlie
Publicado 2022

Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial

por Gershenson, David M, Miller, Austin, Brady, William E, Paul, James, Carty, Karen, Rodgers, William, Millan, David, Coleman, Robert L, Moore, Kathleen N, Banerjee, Susana, Connolly, Kate, Secord, Angeles Alvarez, O'Malley, David M, Dorigo, Oliver, Gaillard, Stephanie, Gabra, Hani, Slomovitz, Brian, Hanjani, Parviz, Farley, John, Churchman, Michael, Ewing, Ailith, Hollis, Robert L, Herrington, C Simon, Huang, Helen Q, Wenzel, Lari, Gourley, Charlie
Publicado 2022

Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes

por Bolton, Kelly L., Chen, Denise, Corona de la Fuente, Rosario, Fu, Zhuxuan, Murali, Rajmohan, Köbel, Martin, Tazi, Yanis, Cunningham, Julie M., Chan, Irenaeus C.C., Wiley, Brian J., Moukarzel, Lea A., Winham, Stacey J., Armasu, Sebastian M., Lester, Jenny, Elishaev, Esther, Laslavic, Angela, Kennedy, Catherine J., Piskorz, Anna, Sekowska, Magdalena, Brand, Alison H., Chiew, Yoke-Eng, Pharoah, Paul, Elias, Kevin M., Drapkin, Ronny, Churchman, Michael, Gourley, Charlie, DeFazio, Anna, Karlan, Beth, Brenton, James D., Weigelt, Britta, Anglesio, Michael S., Huntsman, David, Gayther, Simon, Konner, Jason, Modugno, Francesmary, Lawrenson, Kate, Goode, Ellen L., Papaemmanuil, Elli
Publicado 2022

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

por Houlston, Richard S, Cheadle, Jeremy, Dobbins, Sara E, Tenesa, Albert, Jones, Angela M, Howarth, Kimberley, Spain, Sarah L, Broderick, Peter, Domingo, Enric, Farrington, Susan, Prendergast, James GD, Pittman, Alan M, Theodoratou, Evi, Smith, Christopher G, Olver, Bianca, Walther, Axel, Barnetson, Rebecca A, Churchman, Michael, Jaeger, Emma EM, Penegar, Steven, Barclay, Ella, Martin, Lynn, Gorman, Maggie, Mager, Rachel, Johnstone, Elaine, Midgley, Rachel, Niittymäki, Iina, Tuupanen, Sari, Colley, James, Idziaszczyk, Shelley, Thomas, Huw JM, Lucassen, Anneke M, Evans, D Gareth R, Maher, Eamonn R, Maughan, Timothy, Dimas, Antigone, Dermitzakis, Emmanouil, Cazier, Jean-Baptiste, Aaltonen, Lauri A, Pharoah, Paul, Kerr, David J, Carvajal-Carmona, Luis G, Campbell, Harry, Dunlop, Malcolm G, Tomlinson, Ian PM
Publicado 2010

Therapeutic options for mucinous ovarian carcinoma☆

por Gorringe, Kylie L., Cheasley, Dane, Wakefield, Matthew J., Ryland, Georgina L., Allan, Prue E., Alsop, Kathryn, Amarasinghe, Kaushalya C., Ananda, Sumitra, Bowtell, David D.L., Christie, Michael, Chiew, Yoke-Eng, Churchman, Michael, DeFazio, Anna, Fereday, Sian, Blake Gilks, C., Gourley, Charlie, Hadley, Alison M., Hendley, Joy, Hunter, Sally M., Kaufmann, Scott H., Kennedy, Catherine J., Köbel, Martin, Le Page, Cecile, Li, Jason, Lupat, Richard, McNally, Orla M., McAlpine, Jessica N., Pyman, Jan, Rowley, Simone M., Salazar, Carolina, Saunders, Hugo, Semple, Timothy, Stephens, Andrew N., Thio, Niko, Torres, Michelle C., Traficante, Nadia, Zethoven, Magnus, Antill, Yoland C., Campbell, Ian G., Scott, Clare L.
Publicado 2020

The molecular origin and taxonomy of mucinous ovarian carcinoma

por Cheasley, Dane, Wakefield, Matthew J., Ryland, Georgina L., Allan, Prue E., Alsop, Kathryn, Amarasinghe, Kaushalya C., Ananda, Sumitra, Anglesio, Michael S., Au-Yeung, George, Böhm, Maret, Bowtell, David D. L., Brand, Alison, Chenevix-Trench, Georgia, Christie, Michael, Chiew, Yoke-Eng, Churchman, Michael, DeFazio, Anna, Demeo, Renee, Dudley, Rhiannon, Fairweather, Nicole, Fedele, Clare G., Fereday, Sian, Fox, Stephen B., Gilks, C Blake, Gourley, Charlie, Hacker, Neville F., Hadley, Alison M., Hendley, Joy, Ho, Gwo-Yaw, Hughes, Siobhan, Hunstman, David G., Hunter, Sally M., Jobling, Tom W., Kalli, Kimberly R., Kaufmann, Scott H., Kennedy, Catherine J., Köbel, Martin, Le Page, Cecile, Li, Jason, Lupat, Richard, McNally, Orla M., McAlpine, Jessica N., Mes-Masson, Anne-Marie, Mileshkin, Linda, Provencher, Diane M., Pyman, Jan, Rahimi, Kurosh, Rowley, Simone M., Salazar, Carolina, Samimi, Goli, Saunders, Hugo, Semple, Timothy, Sharma, Ragwha, Sharpe, Alice J., Stephens, Andrew N., Thio, Niko, Torres, Michelle C., Traficante, Nadia, Xing, Zhongyue, Zethoven, Magnus, Antill, Yoland C., Scott, Clare L., Campbell, Ian G., Gorringe, Kylie L.
Publicado 2019