Autophagy, Acute Pancreatitis and the Metamorphoses of a Trypsinogen-Activating Organelle

por Voronina, Svetlana, Chvanov, Michael, De Faveri, Francesca, Mayer, Ulrike, Wileman, Tom, Criddle, David, Tepikin, Alexei
Publicado 2022

Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry

por Walsh, Ciara M., Chvanov, Michael, Haynes, Lee P., Petersen, Ole H., Tepikin, Alexei V., Burgoyne, Robert D.
Publicado 2009

Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis

por Chvanov, Michael, De Faveri, Francesca, Moore, Danielle, Sherwood, Mark W., Awais, Muhammad, Voronina, Svetlana, Sutton, Robert, Criddle, David N., Haynes, Lee, Tepikin, Alexei V.
Publicado 2018

Effects of the Mitochondria-Targeted Antioxidant Mitoquinone in Murine Acute Pancreatitis

por Huang, Wei, Cash, Nicole, Wen, Li, Szatmary, Peter, Mukherjee, Rajarshi, Armstrong, Jane, Chvanov, Michael, Tepikin, Alexei V., Murphy, Michael P., Sutton, Robert, Criddle, David N.
Publicado 2015

Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift

por Armstrong, Jane A., Cash, Nicole J., Ouyang, Yulin, Morton, Jack C., Chvanov, Michael, Latawiec, Diane, Awais, Muhammad, Tepikin, Alexei V., Sutton, Robert, Criddle, David N.
Publicado 2018

The role of Ca(2+) influx in endocytic vacuole formation in pancreatic acinar cells

por Voronina, Svetlana, Collier, David, Chvanov, Michael, Middlehurst, Ben, Beckett, Alison J., Prior, Ian A., Criddle, David N., Begg, Malcolm, Mikoshiba, Katsuhiko, Sutton, Robert, Tepikin, Alexei V.
Publicado 2015

TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester–Induced Mitochondrial Injury and Necrotic Cell Death

por Javed, Muhammad Ahsan, Wen, Li, Awais, Muhammad, Latawiec, Diane, Huang, Wei, Chvanov, Michael, Schaller, Sophie, Bordet, Thierry, Michaud, Magali, Pruss, Rebecca, Tepikin, Alexei, Criddle, David, Sutton, Robert
Publicado 2018

Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does not Reduce Severity of Experimental Acute Pancr...

por Chvanov, Michael, Voronina, Svetlana, Zhang, Xiaoying, Telnova, Svetlana, Chard, Robert, Ouyang, Yulin, Armstrong, Jane, Tanton, Helen, Awais, Muhammad, Latawiec, Diane, Sutton, Robert, Criddle, David N., Tepikin, Alexei V.
Publicado 2020

ATP depletion induces translocation of STIM1 to puncta and formation of STIM1–ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP

por Chvanov, Michael, Walsh, Ciara M., Haynes, Lee P., Voronina, Svetlana G., Lur, Gyorgy, Gerasimenko, Oleg V., Barraclough, Roger, Rudland, Philip S., Petersen, Ole H., Burgoyne, Robert D., Tepikin, Alexei V.
Publicado 2008

Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1

por Ouyang, Yulin, Wen, Li, Armstrong, Jane A., Chvanov, Michael, Latawiec, Diane, Cai, Wenhao, Awais, Mohammad, Mukherjee, Rajarshi, Huang, Wei, Gough, Peter J., Bertin, John, Tepikin, Alexei V., Sutton, Robert, Criddle, David N.
Publicado 2021

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

por Zhang, Xiaoying, Jin, Tao, Shi, Na, Yao, Linbo, Yang, Xinmin, Han, Chenxia, Wen, Li, Du, Dan, Szatmary, Peter, Mukherjee, Rajarshi, Liu, Tingting, Xia, Qing, Criddle, David N., Huang, Wei, Chvanov, Michael, Sutton, Robert
Publicado 2019

LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells

por De Faveri, Francesca, Chvanov, Michael, Voronina, Svetlana, Moore, Danielle, Pollock, Liam, Haynes, Lee, Awais, Muhammad, Beckett, Alison J., Mayer, Ulrike, Sutton, Robert, Criddle, David N., Prior, Ian A., Wileman, Tom, Tepikin, Alexei V.
Publicado 2019

Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release

por Huang, Wei, Cane, Matthew C, Mukherjee, Rajarshi, Szatmary, Peter, Zhang, Xiaoying, Elliott, Victoria, Ouyang, Yulin, Chvanov, Michael, Latawiec, Diane, Wen, Li, Booth, David M, Haynes, Andrea C, Petersen, Ole H, Tepikin, Alexei V, Criddle, David N, Sutton, Robert
Publicado 2017

Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca(2+)-dependent mitochondrial dysfunction and acute pancreatitis

por Huang, Wei, Booth, David M, Cane, Matthew C, Chvanov, Michael, Javed, Muhammad A, Elliott, Victoria L, Armstrong, Jane A, Dingsdale, Hayley, Cash, Nicole, Li, Yan, Greenhalf, William, Mukherjee, Rajarshi, Kaphalia, Bhupendra S, Jaffar, Mohammed, Petersen, Ole H, Tepikin, Alexei V, Sutton, Robert, Criddle, David N
Publicado 2014

Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models

por Wen, Li, Voronina, Svetlana, Javed, Muhammad A., Awais, Muhammad, Szatmary, Peter, Latawiec, Diane, Chvanov, Michael, Collier, David, Huang, Wei, Barrett, John, Begg, Malcolm, Stauderman, Ken, Roos, Jack, Grigoryev, Sergey, Ramos, Stephanie, Rogers, Evan, Whitten, Jeff, Velicelebi, Gonul, Dunn, Michael, Tepikin, Alexei V., Criddle, David N., Sutton, Robert
Publicado 2015

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP

por Mukherjee, Rajarshi, Mareninova, Olga A, Odinokova, Irina V, Huang, Wei, Murphy, John, Chvanov, Michael, Javed, Muhammad A, Wen, Li, Booth, David M, Cane, Matthew C, Awais, Muhammad, Gavillet, Bruno, Pruss, Rebecca M, Schaller, Sophie, Molkentin, Jeffery D, Tepikin, Alexei V, Petersen, Ole H, Pandol, Stephen J, Gukovsky, Ilya, Criddle, David N, Gukovskaya, Anna S, Sutton, Robert
Publicado 2016