Reproducibility of Quantitative Systems Pharmacology Models: Current Challenges and Future Opportunities

por Kirouac, Daniel C., Cicali, Brian, Schmidt, Stephan
Publicado 2019

Comparison of contraceptive failures associated with CYP3A4-inducing drug-drug interactions by route of hormonal contraceptive in an adverse event reporting system

por Sunaga, Tomiko, Cicali, Brian, Schmidt, Stephan, Brown, Joshua
Publicado 2021

Macrolide Treatment Failure due to Drug–Drug Interactions: Real-World Evidence to Evaluate a Pharmacological Hypothesis

por Cicali, Brian, Schmidt, Stephan, Zeitlinger, Markus, Brown, Joshua D.
Publicado 2022

Safety signals for QT prolongation or Torsades de Pointes associated with azithromycin with or without chloroquine or hydroxychloroquine

por Sarayani, Amir, Cicali, Brian, Henriksen, Carl H., Brown, Joshua D.
Publicado 2021

A Valid Warning or Clinical Lore: an Evaluation of Safety Outcomes of Remdesivir in Patients with Impaired Renal Function from a Multicenter Matched Cohort

por Ackley, Tyler W., McManus, Dayna, Topal, Jeffrey E., Cicali, Brian, Shah, Sunish
Publicado 2021

Comparative pharmacovigilance assessment of mortality with pimavanserin in Parkinson disease-related psychosis

por Brown, Joshua D, Cicali, Brian, Henriksen, Carl, Malaty, Irene, Okun, Michael S, Armstrong, Melissa J
Publicado 2021

Physiologically Based Pharmacokinetic Modeling to Assess the Impact of CYP2D6‐Mediated Drug‐Drug Interactions on Tramadol and O‐Desmethyltramadol Exposures via Allosteric and Compe...

por Long, Tao, Cristofoletti, Rodrigo, Cicali, Brian, Michaud, Veronique, Dow, Pamela, Turgeon, Jacques, Schmidt, Stephan
Publicado 2021

Risk Assessment of Drug‐Induced Long QT Syndrome for Some COVID‐19 Repurposed Drugs

por Michaud, Veronique, Dow, Pamela, Al Rihani, Sweilem B., Deodhar, Malavika, Arwood, Meghan, Cicali, Brian, Turgeon, Jacques
Publicado 2020

Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure

por Kim, Soyoung, Cicali, Brian, Pressly, Michelle, Da Silva, Lais, Wendl, Thomas, Vozmediano, Valvanera, Schmidt, Stephan, Cristofoletti, Rodrigo
Publicado 2023

Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug–Drug Interactions of Phenytoin

por Rodriguez-Vera, Leyanis, Yin, Xuefen, Almoslem, Mohammed, Romahn, Karolin, Cicali, Brian, Lukacova, Viera, Cristofoletti, Rodrigo, Schmidt, Stephan
Publicado 2023

Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug‐Drug Interactions Using Physiologically Based Pharmacokinetic Modeling

por Cicali, Brian, Lingineni, Karthik, Cristofoletti, Rodrigo, Wendl, Thomas, Hoechel, Joachim, Wiesinger, Herbert, Chaturvedula, Ayyappa, Vozmediano, Valvanera, Schmidt, Stephan
Publicado 2020

Use of Drug Claims Data and a Medication Risk Score to Assess the Impact of CYP2D6 Drug Interactions among Opioid Users on Healthcare Costs

por Michaud, Veronique, Bikmetov, Ravil, Smith, Matt K., Dow, Pamela, Darakjian, Lucy I., Deodhar, Malavika, Cicali, Brian, Bain, Kevin T., Turgeon, Jacques
Publicado 2021

A Pharmacoepidemiologic Approach to Evaluate Real-world Effectiveness of Hormonal Contraceptives in the Presence of Drug–drug Interactions

por Sarayani, Amir, Brown, Joshua D., Goodin, Amie J., Squires, Patrick, Pham, Phuong, Cicali, Brian, Henriksen, Carl, Schmidt, Stephan, Winterstein, Almut G.
Publicado 2020

Requirements, expectations, challenges and opportunities associated with training the next generation of pharmacometricians

por Schmidt, Stephan, Vozmediano, Valvanera, Cristofoletti, Rodrigo, Kim, Sarah, Lin, Zhoumeng, de Moraes, Natalia, Azeredo, Francine, Cicali, Brian, Leuenberger, Hans, Brown, Joshua D., Jin, Jin Y., Musante, Cynthia J., Tannenbaum, Stacey, Wang, Yaning
Publicado 2023