TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization

por Galati, Alessandra, Micheli, Emanuela, Alicata, Claudia, Ingegnere, Tiziano, Cicconi, Alessandro, Pusch, Miriam Caroline, Giraud-Panis, Marie-Josèphe, Gilson, Eric, Cacchione, Stefano
Publicado 2015

Evidence for a quadruplex structure in the polymorphic hs1.2 enhancer of the immunoglobulin heavy chain 3’ regulatory regions and its conservation in mammals

por Sette, Marco, D'Addabbo, Pietro, Kelly, Geoffrey, Cicconi, Alessandro, Micheli, Emanuela, Cacchione, Stefano, Poma, Anna, Gargioli, Cesare, Giambra, Vincenzo, Frezza, Domenico
Publicado 2016

Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly

por Cicconi, Alessandro, Rai, Rekha, Xiong, Xuexue, Broton, Cayla, Al-Hiyasat, Amer, Hu, Chunyi, Dong, Siying, Sun, Wenqi, Garbarino, Jennifer, Bindra, Ranjit S., Schildkraut, Carl, Chen, Yong, Chang, Sandy
Publicado 2020

The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response

por Cicconi, Alessandro, Micheli, Emanuela, Vernì, Fiammetta, Jackson, Alison, Gradilla, Ana Citlali, Cipressa, Francesca, Raimondo, Domenico, Bosso, Giuseppe, Wakefield, James G., Ciapponi, Laura, Cenci, Giovanni, Gatti, Maurizio, Cacchione, Stefano, Raffa, Grazia Daniela
Publicado 2017

Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models

por Rodriguez-Berriguete, Gonzalo, Ranzani, Marco, Prevo, Remko, Puliyadi, Rathi, Machado, Nicole, Bolland, Hannah R., Millar, Val, Ebner, Daniel, Boursier, Marie, Cerutti, Aurora, Cicconi, Alessandro, Galbiati, Alessandro, Grande, Diego, Grinkevich, Vera, Majithiya, Jayesh B., Piscitello, Desiree, Rajendra, Eeson, Stockley, Martin L., Boulton, Simon J., Hammond, Ester M., Heald, Robert A., Smith, Graeme C.M., Robinson, Helen M.R., Higgins, Geoff S.
Publicado 2023