The molecular landscape of adult diffuse gliomas and relevance to clinical trials

por Cimino, Patrick J., Holland, Eric C.
Publicado 2019

Neuropathologic features of central nervous system hemangioblastoma

por Yoda, Rebecca A., Cimino, Patrick J.
Publicado 2022

Machine learning modeling of genome-wide copy number alteration signatures reliably predicts IDH mutational status in adult diffuse glioma

por Nuechterlein, Nicholas, Shapiro, Linda G., Holland, Eric C., Cimino, Patrick J.
Publicado 2021

Video-Mosaicked Handheld Dual-Axis Confocal Microscopy of Gliomas: An ex vivo Feasibility Study in Humans

por Fujita, Yoko, Wei, Linpeng, Cimino, Patrick J., Liu, Jonathan T. C., Sanai, Nader
Publicado 2020

ABCG1 maintains high-grade glioma survival in vitro and in vivo

por Chen, Yi-Hsien, Cimino, Patrick J., Luo, Jingqin, Dahiya, Sonika, Gutmann, David H.
Publicado 2016

Neurotrophic Receptor Tyrosine Kinase 2 (NTRK2) Alterations in Low-Grade Gliomas: Report of a Novel Gene Fusion Partner in a Pilocytic Astrocytoma and Review of the Literature

por Pattwell, Siobhan S., Konnick, Eric Q., Liu, Yajuan J., Yoda, Rebecca A., Sekhar, Laligam N., Cimino, Patrick J.
Publicado 2020

Phenotypic characterization with somatic genome editing and gene transfer reveals the diverse oncogenicity of ependymoma fusion genes

por Takadera, Mutsumi, Satomi, Kaishi, Szulzewsky, Frank, Cimino, Patrick J., Holland, Eric C., Yamamoto, Tetsuya, Ichimura, Koichi, Ozawa, Tatsuya
Publicado 2020

Radiogenomic modeling predicts survival-associated prognostic groups in glioblastoma

por Nuechterlein, Nicholas, Li, Beibin, Feroze, Abdullah, Holland, Eric C, Shapiro, Linda, Haynor, David, Fink, James, Cimino, Patrick J
Publicado 2021

Intraoperative assessment of skull base tumors using stimulated Raman scattering microscopy

por Shin, Kseniya S., Francis, Andrew T., Hill, Andrew H., Laohajaratsang, Mint, Cimino, Patrick J., Latimer, Caitlin S., Gonzalez-Cuyar, Luis F., Sekhar, Laligam N., Juric-Sekhar, Gordana, Fu, Dan
Publicado 2019

Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice

por Szulzewsky, Frank, Arora, Sonali, Arakaki, Aleena K.S., Sievers, Philipp, Almiron Bonnin, Damian A., Paddison, Patrick J., Sahm, Felix, Cimino, Patrick J., Gujral, Taranjit S., Holland, Eric C.
Publicado 2022

Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery

por Cimino, Patrick J., Zager, Michael, McFerrin, Lisa, Wirsching, Hans-Georg, Bolouri, Hamid, Hentschel, Bettina, von Deimling, Andreas, Jones, David, Reifenberger, Guido, Weller, Michael, Holland, Eric C.
Publicado 2017

Recurrent switch 2 domain RAC2 mutations in intravascular large B-cell lymphoma

por Kodgule, Rohan, Chen, Jie, Khonde, Pooja, Robinson, Joshua, D’Albora, Amy, Cook, Lisa, Fronick, Catrina C., Fulton, Robert, Srivatsan, Sridhar Nonavinkere, Cimino, Patrick J., Duncavage, Eric J.
Publicado 2022

The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation

por Solga, Anne C, Toonen, Joseph A, Pan, Yuan, Cimino, Patrick J, Ma, Yu, Castillon, Guillaume A, Gianino, Scott M, Ellisman, Mark H, Lee, Da Yong, Gutmann, David H
Publicado 2017

Plinabulin, an inhibitor of tubulin polymerization, targets KRAS signaling through disruption of endosomal recycling

por Cimino, Patrick J., Huang, Lan, Du, Lihua, Wu, Yanping, Bishop, Jamie, Dalsing-Hernandez, Jessica, Kotlarczyk, Kari, Gonzales, Paul, Carew, Jennifer, Nawrocki, Steffan, Jordan, Mary Ann, Wilson, Leslie, Lloyd, G. Kenneth, Wirsching, Hans-Georg
Publicado 2019

Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma

por Cimino, Patrick J., Kim, Youngmi, Wu, Hua-Jun, Alexander, Jes, Wirsching, Hans-Georg, Szulzewsky, Frank, Pitter, Ken, Ozawa, Tatsuya, Wang, Jiguang, Vazquez, Julio, Arora, Sonali, Rabadan, Raul, Levine, Ross, Michor, Franziska, Holland, Eric C.
Publicado 2018

A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis

por Horne, Eric A, Diaz, Philippe, Cimino, Patrick J, Jung, Erik, Xu, Cong, Hamel, Ernest, Wagenbach, Michael, Kumasaka, Debra, Wageling, Nicholas B, Azorín, Daniel D, Winkler, Frank, Wordeman, Linda G, Holland, Eric C, Stella, Nephi
Publicado 2020

Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis

por Szulzewsky, Frank, Arora, Sonali, Hoellerbauer, Pia, King, Claire, Nathan, Erica, Chan, Marina, Cimino, Patrick J., Ozawa, Tatsuya, Kawauchi, Daisuke, Pajtler, Kristian W., Gilbertson, Richard J., Paddison, Patrick J., Vasioukhin, Valeri, Gujral, Taranjit S., Holland, Eric C.
Publicado 2020

A single-cell based precision medicine approach using glioblastoma patient-specific models

por Park, James H., Feroze, Abdullah H., Emerson, Samuel N., Mihalas, Anca B., Keene, C. Dirk, Cimino, Patrick J., de Lomana, Adrian Lopez Garcia, Kannan, Kavya, Wu, Wei-Ju, Turkarslan, Serdar, Baliga, Nitin S., Patel, Anoop P.
Publicado 2022

Spatial immune profiling of glioblastoma identifies an inflammatory, perivascular phenotype associated with longer survival

por Wirsching, Hans-Georg, Felsberg, Jörg, Prummer, Michael, Moisoiu, Vlad, Lourman, Roxanne, Hertler, Caroline, Antonios, Michelle, Cimino, Patrick J., Roth, Patrick, Gorlia, Thierry, Prins, Robert M., Cloughesy, Timothy, Wen, Patrick Y., Holland, Eric C., Reifenberger, Guido, Weller, Michael
Publicado 2023

RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth()

por Solga, Anne C., Pong, Winnie W., Kim, Keun-Young, Cimino, Patrick J., Toonen, Joseph A., Walker, Jason, Wylie, Todd, Magrini, Vincent, Griffith, Malachi, Griffith, Obi L., Ly, Amy, Ellisman, Mark H., Mardis, Elaine R., Gutmann, David H.
Publicado 2015