Robust Target Gene Discovery through Transcriptome Perturbations and Genome-Wide Enhancer Predictions in Drosophila Uncovers a Regulatory Basis for Sensory Specification

por Aerts, Stein, Quan, Xiao-Jiang, Claeys, Annelies, Naval Sanchez, Marina, Tate, Phillip, Yan, Jiekun, Hassan, Bassem A.
Publicado 2010

The Drosophila neurogenin Tap functionally interacts with the Wnt-PCP pathway to regulate neuronal extension and guidance

por Yuan, Liqun, Hu, Shu, Okray, Zeynep, Ren, Xi, De Geest, Natalie, Claeys, Annelies, Yan, Jiekun, Bellefroid, Eric, Hassan, Bassem A., Quan, Xiao-Jiang
Publicado 2016

Evolutionary changes in transcription factor coding sequence quantitatively alter sensory organ development and function

por Weinberger, Simon, Topping, Matthew P, Yan, Jiekun, Claeys, Annelies, Geest, Natalie De, Ozbay, Duru, Hassan, Talah, He, Xiaoli, Albert, Joerg T, Hassan, Bassem A, Ramaekers, Ariane
Publicado 2017

A Fat-Facets-Dscam1-JNK Pathway Enhances Axonal Growth in Development and after Injury

por Koch, Marta, Nicolas, Maya, Zschaetzsch, Marlen, de Geest, Natalie, Claeys, Annelies, Yan, Jiekun, Morgan, Matthew J., Erfurth, Maria-Luise, Holt, Matthew, Schmucker, Dietmar, Hassan, Bassem A.
Publicado 2018

The amyloid precursor protein is a conserved Wnt receptor

por Liu, Tengyuan, Zhang, Tingting, Nicolas, Maya, Boussicault, Lydie, Rice, Heather, Soldano, Alessia, Claeys, Annelies, Petrova, Iveta, Fradkin, Lee, De Strooper, Bart, Potier, Marie-Claude, Hassan, Bassem A
Publicado 2021

The Drosophila Homologue of the Amyloid Precursor Protein Is a Conserved Modulator of Wnt PCP Signaling

por Soldano, Alessia, Okray, Zeynep, Janovska, Pavlina, Tmejová, Kateřina, Reynaud, Elodie, Claeys, Annelies, Yan, Jiekun, Atak, Zeynep Kalender, De Strooper, Bart, Dura, Jean-Maurice, Bryja, Vítězslav, Hassan, Bassem A.
Publicado 2013

A novel fragile X syndrome mutation reveals a conserved role for the carboxy-terminus in FMRP localization and function

por Okray, Zeynep, de Esch, Celine EF, Van Esch, Hilde, Devriendt, Koen, Claeys, Annelies, Yan, Jiekun, Verbeeck, Jelle, Froyen, Guy, Willemsen, Rob, de Vrij, Femke MS, Hassan, Bassem A
Publicado 2015

OTHR-38. The development of patient-derived models of pediatric brain tumors

por Messiaen, Julie, Derweduwe, Marleen, Claeys, Annelies, Solie, Lien, Sciot, Raf, Bempt, Isabelle Vanden, Devleeschouwer, Steven, Van Calenbergh, Frank, De Vloo, Philippe, Depreitere, Bart, Jacobs, Sandra, De Smet, Frederik
Publicado 2022

OTHR-39. Extraneural spreading of a diffuse leptomeningeal glioneuronal tumor in a child: patient-derived models show sensitivity to vinblastin and trametinib

por Messiaen, Julie, Claeys, Annelies, Shetty, Aniket, Spans, Lien, Derweduwe, Marleen, Uyttebroeck, Anne, Depreitere, Bart, Bempt, Isabelle Vanden, Sciot, Raf, Ligon, Keith, Jones, David, Jacobs, Sandra, De Smet, Frederik
Publicado 2022

Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex

por Oliva, Carlos, Soldano, Alessia, Mora, Natalia, De Geest, Natalie, Claeys, Annelies, Erfurth, Maria-Luise, Sierralta, Jimena, Ramaekers, Ariane, Dascenco, Dan, Ejsmont, Radoslaw K., Schmucker, Dietmar, Sanchez-Soriano, Natalia, Hassan, Bassem A.
Publicado 2016

A simple computer vision pipeline reveals the effects of isolation on social interaction dynamics in Drosophila

por Liu, Guangda, Nath, Tanmay, Linneweber, Gerit A., Claeys, Annelies, Guo, Zhengyu, Li, Jin, Bengochea, Mercedes, De Backer, Steve, Weyn, Barbara, Sneyders, Manu, Nicasy, Hans, Yu, Peng, Scheunders, Paul, Hassan, Bassem A.
Publicado 2018

Generation of patient-derived models from a metastatic pediatric diffuse leptomeningeal glioneuronal tumor with KIAA1549::BRAF fusion

por Messiaen, Julie, Claeys, Annelies, Shetty, Aniket, Spans, Lien, Derweduwe, Marleen, Uyttebroeck, Anne, Depreitere, Bart, Vanden Bempt, Isabelle, Sciot, Raf, Ligon, Keith L., Jones, David T. W., Jacobs, Sandra A., De Smet, Frederik
Publicado 2022

Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation

por Naus, Evelyne, Derweduwe, Marleen, Lampi, Youlia, Claeys, Annelies, Pauwels, Jarne, Langenberg, Tobias, Claes, Filip, Xu, Jie, Haemels, Veerle, Atak, Zeynep Kalender, van der Kant, Rob, Van Durme, Joost, De Baets, Greet, Ligon, Keith L., Fiers, Mark, Gevaert, Kris, Aerts, Stein, Rousseau, Frederic, Schymkowitz, Joost, De Smet, Frederik
Publicado 2023

Single‐cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

por Finotto, Lise, Cole, Basiel, Giese, Wolfgang, Baumann, Elisabeth, Claeys, Annelies, Vanmechelen, Maxime, Decraene, Brecht, Derweduwe, Marleen, Dubroja Lakic, Nikolina, Shankar, Gautam, Nagathihalli Kantharaju, Madhu, Albrecht, Jan Philipp, Geudens, Ilse, Stanchi, Fabio, Ligon, Keith L, Boeckx, Bram, Lambrechts, Diether, Harrington, Kyle, Van Den Bosch, Ludo, De Vleeschouwer, Steven, De Smet, Frederik, Gerhardt, Holger
Publicado 2023