How can we obtain truly translational mouse models to improve clinical outcomes in schizophrenia?

por Clapcote, Steven J.
Publicado 2022

Characterization of Cognitive Deficits in Mice With an Alternating Hemiplegia-Linked Mutation

por Kirshenbaum, Greer S., Dachtler, James, Roder, John C., Clapcote, Steven J.
Publicado 2015

Transgenic rescue of phenotypic deficits in a mouse model of alternating hemiplegia of childhood

por Kirshenbaum, Greer S., Dachtler, James, Roder, John C., Clapcote, Steven J.
Publicado 2015

Genetically altered animal models for ATP1A3-related disorders

por Ng, Hannah W. Y., Ogbeta, Jennifer A., Clapcote, Steven J.
Publicado 2021

Missense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in mice

por Dachtler, James, Elliott, Christina, Rodgers, R. John, Baillie, George S., Clapcote, Steven J.
Publicado 2016

Deficits in social behavioral tests in a mouse model of alternating hemiplegia of childhood

por Kirshenbaum, Greer S., Idris, Nagi F., Dachtler, James, Roder, John C., Clapcote, Steven J.
Publicado 2016

Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behavior in a mouse model of autism‐associated 2p16.3 deletion

por Hughes, Rebecca B., Whittingham‐Dowd, Jayde, Clapcote, Steven J., Broughton, Susan J., Dawson, Neil
Publicado 2022

Heterozygous Deletion of α-Neurexin I or α-Neurexin II Results in Behaviors Relevant to Autism and Schizophrenia

por Dachtler, James, Ivorra, Jose L., Rowland, Tessa E., Lever, Colin, Rodgers, R. John, Clapcote, Steven J.
Publicado 2015

Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion

por B Hughes, Rebecca, Whittingham-Dowd, Jayde, Simmons, Rachel E, Clapcote, Steven J, Broughton, Susan J, Dawson, Neil
Publicado 2020

Mice Lacking Ras-GRF1 Show Contextual Fear Conditioning but not Spatial Memory Impairments: Convergent Evidence from Two Independently Generated Mouse Mutant Lines

por d’Isa, Raffaele, Clapcote, Steven J., Voikar, Vootele, Wolfer, David P., Giese, Karl Peter, Brambilla, Riccardo, Fasano, Stefania
Publicado 2011

Disc1 Variation Leads to Specific Alterations in Adult Neurogenesis

por Chandran, Jayanth S., Kazanis, Ilias, Clapcote, Steven J., Ogawa, Fumiaki, Millar, J. Kirsty, Porteous, David J., ffrench-Constant, Charles
Publicado 2014

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice

por Pervolaraki, Eleftheria, Tyson, Adam L., Pibiri, Francesca, Poulter, Steven L., Reichelt, Amy C., Rodgers, R. John, Clapcote, Steven J., Lever, Colin, Andreae, Laura C., Dachtler, James
Publicado 2019

Alternating Hemiplegia of Childhood-Related Neural and Behavioural Phenotypes in Na(+),K(+)-ATPase α3 Missense Mutant Mice

por Kirshenbaum, Greer S., Dawson, Neil, Mullins, Jonathan G. L., Johnston, Tom H., Drinkhill, Mark J., Edwards, Ian J., Fox, Susan H., Pratt, Judith A., Brotchie, Jonathan M., Roder, John C., Clapcote, Steven J.
Publicado 2013

Circadian Disruptions in the Myshkin Mouse Model of Mania Are Independent of Deficits in Suprachiasmatic Molecular Clock Function

por Timothy, Joseph W.S., Klas, Natasza, Sanghani, Harshmeena R., Al-Mansouri, Taghreed, Hughes, Alun T.L., Kirshenbaum, Greer S., Brienza, Vincent, Belle, Mino D.C., Ralph, Martin R., Clapcote, Steven J., Piggins, Hugh D.
Publicado 2018

In memory of Professor Iain Wilkinson: cognitive and neuroimaging endophenotypes in a consanguineous schizophrenia multiplex family

por Wilkinson, Iain D., Mahmood, Tariq, Yasmin, Sophia Faye, Tomlinson, Anneka, Nazari, Jamshid, Alhaj, Hamid, el din, Soumaya Nasser, Neill, Joanna, Pandit, Chhaya, Ashraf, Shahzad, Cardno, Alastair G., Clapcote, Steven J., Inglehearn, Chris F., Woodruff, Peter W.
Publicado 2023

Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition

por McGirr, Alexander, Lipina, Tatiana V, Mun, Ho-Suk, Georgiou, John, Al-Amri, Ahmed H, Ng, Enoch, Zhai, Dongxu, Elliott, Christina, Cameron, Ryan T, Mullins, Jonathan GL, Liu, Fang, Baillie, George S, Clapcote, Steven J, Roder, John C
Publicado 2016

Neto1 Is a Novel CUB-Domain NMDA Receptor–Interacting Protein Required for Synaptic Plasticity and Learning

por Ng, David, Pitcher, Graham M, Szilard, Rachel K, Sertié, Andréa, Kanisek, Marijana, Clapcote, Steven J, Lipina, Tatiana, Kalia, Lorraine V, Joo, Daisy, McKerlie, Colin, Cortez, Miguel, Roder, John C, Salter, Michael W, McInnes, Roderick R
Publicado 2009

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A

por Cheung, Sin Ying, Henrot, Matthias, Al-Saad, Mohammad, Baumann, Matthias, Muller, Heiko, Unger, Anke, Rubaiy, Hussein N., Mathar, Ilka, Dinkel, Klaus, Nussbaumer, Peter, Klebl, Bert, Freichel, Marc, Rode, Baptiste, Trainor, Sebastian, Clapcote, Steven J., Christmann, Mathias, Waldmann, Herbert, Abbas, Syed Khawar, Beech, David J., Vasudev, Naveen S.
Publicado 2018

A Recessively Inherited Risk Locus on Chromosome 13q22-31 Conferring Susceptibility to Schizophrenia

por Mahmood, Tariq, El-Asrag, Mohammed E, Poulter, James A, Cardno, Alastair G, Tomlinson, Anneka, Ahmed, Sophia, Al-Amri, Ahmed, Nazari, Jamshid, Neill, Joanna, Chamali, Rifka S, Kiwan, Nancy, Ghuloum, Suhaila, Alhaj, Hamid A, Randerson Moor, Juliette, Khan, Shabana, Al-Amin, Hassen, Johnson, Colin A, Woodruff, Peter, Wilkinson, Iain D, Ali, Manir, Clapcote, Steven J, Inglehearn, Chris F
Publicado 2020

PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies

por Al-Amri, Ahmed H., Armstrong, Paul, Amici, Mascia, Ligneul, Clemence, Rouse, James, El-Asrag, Mohammed E., Pantiru, Andreea, Vancollie, Valerie E., Ng, Hannah W.Y., Ogbeta, Jennifer A., Goodchild, Kirstie, Ellegood, Jacob, Lelliott, Christopher J., Mullins, Jonathan G.L., Bretman, Amanda, Al-Ali, Ruslan, Beetz, Christian, Al-Gazali, Lihadh, Al Shamsi, Aisha, Lerch, Jason P., Mellor, Jack R., Al Sayegh, Abeer, Ali, Manir, Inglehearn, Chris F., Clapcote, Steven J.
Publicado 2022