Lkb1 and Pten Synergise to Suppress mTOR-Mediated Tumorigenesis and Epithelial-Mesenchymal Transition in the Mouse Bladder

por Shorning, Boris Y., Griffiths, David, Clarke, Alan R.
Publicado 2011

Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation

por Greenow, Kirsty R., Clarke, Alan R., Jones, Robert H.
Publicado 2009

Evidence for a Crucial Role of Paneth Cells in Mediating the Intestinal Response to Injury

por Parry, Lee, Young, Madeleine, El Marjou, Fatima, Clarke, Alan R
Publicado 2013

Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis

por Thomas, Rhian S, Clarke, Alan R, Duance, Victor C, Blain, Emma J
Publicado 2011

Absence of p53 in Clara cells favours multinucleation and loss of cell cycle arrest

por Armit, Christopher J, O'Dea, Shirley, Clarke, Alan R, Harrison, David J
Publicado 2002

Oral Prion Neuroinvasion Occurs Independently of PrP(C) Expression in the Gut Epithelium

por Marshall, Alison, Bradford, Barry M., Clarke, Alan R., Manson, Jean C., Mabbott, Neil A.
Publicado 2018

APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression

por Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R., Smalley, Matthew J., Clarke, Alan R.
Publicado 2019

Caspase-dependent proteolytic cleavage of STAT3α in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines

por Matthews, James R, Watson, Susan MR, Tevendale, Maxine CL, Watson, Christine J, Clarke, Alan R
Publicado 2007

A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine

por Reed, Karen R, Meniel, Valerie S, Marsh, Victoria, Cole, Alicia, Sansom, Owen J, Clarke, Alan R
Publicado 2008

Apc and p53 interaction in DNA damage and genomic instability in hepatocytes

por Méniel, Valérie, Megges, Matthias, Young, Madeleine A, Cole, Alicia, Sansom, Owen J, Clarke, Alan R
Publicado 2014

Analysis of Fascin-1 in Relation to Gleason Risk Classification and Nuclear ETS-Related Gene Status of Human Prostate Carcinomas: An Immunohistochemical Study of Clinically Annotat...

por Jefferies, Matthew T, Pope, Christopher S, Kynaston, Howard G, Clarke, Alan R, Martin, Richard M, Adams, Josephine C
Publicado 2017

Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine

por Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T., Metzger, Daniel, Shorning, Boris Y., Clarke, Alan R.
Publicado 2014

PPARδ status and mismatch repair mediated neoplasia in the mouse intestine

por Reed, Karen R, Sansom, Owen J, Hayes, Anthony J, Gescher, Andreas J, Peters, Jeffrey M, Clarke, Alan R
Publicado 2006

Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway

por Burke, Zoë D., Reed, Karen R., Yeh, Sheng-Wen, Meniel, Valerie, Sansom, Owen J., Clarke, Alan R., Tosh, David
Publicado 2018

Author Correction: Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway

por Burke, Zoë D., Reed, Karen R., Yeh, Sheng-Wen, Meniel, Valerie, Sansom, Owen J., Clarke, Alan R., Tosh, David
Publicado 2020

p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

por Cole, Alicia M, Ridgway, Rachel A, Derkits, Sahra E, Parry, Lee, Barker, Nick, Clevers, Hans, Clarke, Alan R, Sansom, Owen J
Publicado 2010

Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

por Shorning, Boris Y., Zabkiewicz, Joanna, McCarthy, Afshan, Pearson, Helen B., Winton, Douglas J., Sansom, Owen J., Ashworth, Alan, Clarke, Alan R.
Publicado 2009

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

por Shorning, Boris Y., Zabkiewicz, Joanna, McCarthy, Afshan, Pearson, Helen B., Winton, Douglas J., Sansom, Owen J., Ashworth, Alan, Clarke, Alan R.
Publicado 2009

In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system

por Jardé, Thierry, Evans, Rebecca J, McQuillan, Karina L, Parry, Lee, Feng, Gui Jie, Alvares, Bernardo, Clarke, Alan R, Dale, Trevor C
Publicado 2012

Hunk/Mak-v is a negative regulator of intestinal cell proliferation

por Reed, Karen R, Korobko, Igor V, Ninkina, Natalia, Korobko, Elena V, Hopkins, Ben R, Platt, James L, Buchman, Vladimir, Clarke, Alan R
Publicado 2015