Peptidoglycan O-Acetylation as a Virulence Factor: Its Effect on Lysozyme in the Innate Immune System

por Brott, Ashley S., Clarke, Anthony J.
Publicado 2019

Development of a High Throughput Screen for the Identification of Inhibitors of Peptidoglycan O-Acetyltransferases, New Potential Antibacterial Targets

por Brott, Ashley S., Jones, Carys S., Clarke, Anthony J.
Publicado 2019

Identification of a new family of enzymes with potential O-acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria

por Weadge, Joel T, Pfeffer, John M, Clarke, Anthony J
Publicado 2005

Mechanistic Pathways for Peptidoglycan O-Acetylation and De-O-Acetylation

por Sychantha, David, Brott, Ashley S., Jones, Carys S., Clarke, Anthony J.
Publicado 2018

O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport

por Seepersaud, Ravin, Sychantha, David, Bensing, Barbara A., Clarke, Anthony J., Sullam, Paul M.
Publicado 2017

The SGNH hydrolase family: a template for carbohydrate diversity

por Anderson, Alexander C, Stangherlin, Stefen, Pimentel, Kyle N, Weadge, Joel T, Clarke, Anthony J
Publicado 2022

O-acetylation controls the glycosylation of bacterial serine-rich repeat glycoproteins

por Seepersaud, Ravin, Anderson, Alexander C., Bensing, Barbara A., Choudhury, Biswa P., Clarke, Anthony J., Sullam, Paul M.
Publicado 2021

Pseudomonas aeruginosa Alters Peptidoglycan Composition under Nutrient Conditions Resembling Cystic Fibrosis Lung Infections

por Anderson, Erin M., Shaji Saji, Neethu, Anderson, Alexander C., Brewer, Dyanne, Clarke, Anthony J., Khursigara, Cezar M.
Publicado 2022

Collateral Changes in Cell Physiology Associated with ADC-7 β-Lactamase Expression in Acinetobacter baumannii

por Colquhoun, Jennifer M., Farokhyfar, Marjan, Anderson, Alexander C., Bethel, Christopher R., Bonomo, Robert A., Clarke, Anthony J., Rather, Philip N.
Publicado 2023

OXA-23 β-Lactamase Overexpression in Acinetobacter baumannii Drives Physiological Changes Resulting in New Genetic Vulnerabilities

por Colquhoun, Jennifer M., Farokhyfar, Marjan, Hutcheson, Anna R., Anderson, Alexander, Bethel, Christopher R., Bonomo, Robert A., Clarke, Anthony J., Rather, Philip N.
Publicado 2021

Accumulation of Peptidoglycan O-Acetylation Leads to Altered Cell Wall Biochemistry and Negatively Impacts Pathogenesis Factors of Campylobacter jejuni

por Ha, Reuben, Frirdich, Emilisa, Sychantha, David, Biboy, Jacob, Taveirne, Michael E., Johnson, Jeremiah G., DiRita, Victor J., Vollmer, Waldemar, Clarke, Anthony J., Gaynor, Erin C.
Publicado 2016

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA)

por Sychantha, David, Jones, Carys S., Little, Dustin J., Moynihan, Patrick J., Robinson, Howard, Galley, Nicola F., Roper, David I., Dowson, Christopher G., Howell, P. Lynne, Clarke, Anthony J.
Publicado 2017

Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

por Maranha, Ana, Moynihan, Patrick J., Miranda, Vanessa, Correia Lourenço, Eva, Nunes-Costa, Daniela, Fraga, Joana S., José Barbosa Pereira, Pedro, Macedo-Ribeiro, Sandra, Ventura, M. Rita, Clarke, Anthony J., Empadinhas, Nuno
Publicado 2015

P. aeruginosa SGNH Hydrolase-Like Proteins AlgJ and AlgX Have Similar Topology but Separate and Distinct Roles in Alginate Acetylation

por Baker, Perrin, Ricer, Tyler, Moynihan, Patrick J., Kitova, Elena N., Walvoort, Marthe T. C., Little, Dustin J., Whitney, John C., Dawson, Karen, Weadge, Joel T., Robinson, Howard, Ohman, Dennis E., Codée, Jeroen D. C., Klassen, John S., Clarke, Anthony J., Howell, P. Lynne
Publicado 2014