What Can RNA-Based Therapy Do for Monogenic Diseases?

por Clarke, Luka A., Amaral, Margarida D.
Publicado 2023

Extracting microRNA-gene relations from biomedical literature using distant supervision

por Lamurias, Andre, Clarke, Luka A., Couto, Francisco M.
Publicado 2017

Annotation extension through protein family annotation coherence metrics

por Bastos, Hugo P., Clarke, Luka A., Couto, Francisco M.
Publicado 2013

Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies

por Clarke, Luka A, Sousa, Lisete, Barreto, Celeste, Amaral, Margarida D
Publicado 2013

BO-LSTM: classifying relations via long short-term memory networks along biomedical ontologies

por Lamurias, Andre, Sousa, Diana, Clarke, Luka A., Couto, Francisco M.
Publicado 2019

GRYFUN: A Web Application for GO Term Annotation Visualization and Analysis in Protein Sets

por Bastos, Hugo P., Sousa, Lisete, Clarke, Luka A., Couto, Francisco M.
Publicado 2015

Functional coherence metrics in protein families

por Bastos, Hugo P., Sousa, Lisete, Clarke, Luka A., Couto, Francisco M.
Publicado 2016

Generating a Tolerogenic Cell Therapy Knowledge Graph from Literature

por Lamurias, Andre, Ferreira, João D., Clarke, Luka A., Couto, Francisco M.
Publicado 2017

KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway

por Sousa, Luis, Pankonien, Ines, Clarke, Luka A, Silva, Iris, Kunzelmann, Karl, Amaral, Margarida D
Publicado 2020

Integrity and Stability of PTC Bearing CFTR mRNA and Relevance to Future Modulator Therapies in Cystic Fibrosis

por Clarke, Luka A., Luz, Vanessa C. C., Targowski, Szymon, Ramalho, Sofia S., Farinha, Carlos M., Amaral, Margarida D.
Publicado 2021

TMEM16A chloride channel does not drive mucus production

por Simões, Filipa B, Quaresma, Margarida C, Clarke, Luka A, Silva, Iris AL, Pankonien, Ines, Railean, Violeta, Kmit, Arthur, Amaral, Margarida D
Publicado 2019

Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis

por Awatade, Nikhil T., Uliyakina, Inna, Farinha, Carlos M., Clarke, Luka A., Mendes, Karina, Solé, Amparo, Pastor, Juan, Ramos, Maria Margarida, Amaral, Margarida D.
Publicado 2014

Mutant CFTR Drives TWIST1 mediated epithelial–mesenchymal transition

por Quaresma, Margarida C., Pankonien, Ines, Clarke, Luka A., Sousa, Luís S., Silva, Iris A. L., Railean, Violeta, Doušová, Tereza, Fuxe, Jonas, Amaral, Margarida D.
Publicado 2020

Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells

por Bene, Zsolt, Fejes, Zsolt, Szanto, Tibor Gabor, Fenyvesi, Ferenc, Váradi, Judit, Clarke, Luka A., Panyi, Gyorgy, Macek, Milan, Amaral, Margarida D., Balogh, István, Nagy, Béla
Publicado 2021

Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei

por Zink, Daniele, Amaral, Margarida D., Englmann, Andreas, Lang, Susanne, Clarke, Luka A., Rudolph, Carsten, Alt, Felix, Luther, Kathrin, Braz, Carla, Sadoni, Nicolas, Rosenecker, Joseph, Schindelhauer, Dirk
Publicado 2004