Associations of urological malignancies with renal progression and mortality in advanced chronic kidney disease: a propensity-matched cohort study

por Chinnadurai, Rajkumar, Clarke, Noel W., Kalra, Philip A.
Publicado 2020

Robot-assisted radical prostatectomy vs laparoscopic and open retropubic radical prostatectomy: functional outcomes 18 months after diagnosis from a national cohort study in Englan...

por Nossiter, Julie, Sujenthiran, Arunan, Charman, Susan C, Cathcart, Paul J, Aggarwal, Ajay, Payne, Heather, Clarke, Noel W, van der Meulen, Jan
Publicado 2018

Impact of cancer service centralisation on the radical treatment of men with high‐risk and locally advanced prostate cancer: A national cross‐sectional analysis in England

por Parry, Matthew G, Sujenthiran, Arunan, Cowling, Thomas E, Nossiter, Julie, Cathcart, Paul, Clarke, Noel W, Payne, Heather, Aggarwal, Ajay, van der Meulen, Jan
Publicado 2019

National cohort study comparing severe medium‐term urinary complications after robot‐assisted vs laparoscopic vs retropubic open radical prostatectomy

por Sujenthiran, Arunan, Nossiter, Julie, Parry, Matthew, Charman, Susan C., Aggarwal, Ajay, Payne, Heather, Dasgupta, Prokar, Clarke, Noel W., van der Meulen, Jan, Cathcart, Paul
Publicado 2017

Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

por Sydes, Matthew R, Parmar, Mahesh KB, James, Nicholas D, Clarke, Noel W, Dearnaley, David P, Mason, Malcolm D, Morgan, Rachel C, Sanders, Karen, Royston, Patrick
Publicado 2009

Automated quantitative high-throughput multiplex immunofluorescence pipeline to evaluate OXPHOS defects in formalin-fixed human prostate tissue

por Sachdeva, Ashwin, Hart, Claire A., Carey, Christopher D., Vincent, Amy E., Greaves, Laura C., Heer, Rakesh, Oliveira, Pedro, Brown, Michael D., Clarke, Noel W., Turnbull, Doug M.
Publicado 2022

Treatment-related toxicity using prostate bed versus prostate bed and pelvic lymph node radiation therapy following radical prostatectomy: A national population-based study

por Sujenthiran, Arunan, Parry, Matthew G., Dodkins, Joanna, Nossiter, Julie, Morris, Melanie, Berry, Brendan, Nathan, Arjun, Cathcart, Paul, Clarke, Noel W., Payne, Heather, van der Meulen, Jan, Aggarwal, Ajay
Publicado 2023

CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma

por McRonald, Fiona E, Morris, Mark R, Gentle, Dean, Winchester, Laura, Baban, Dilair, Ragoussis, Jiannis, Clarke, Noel W, Brown, Michael D, Kishida, Takeshi, Yao, Masahiro, Latif, Farida, Maher, Eamonn R
Publicado 2009

Cardiovascular Safety of Degarelix Versus Leuprolide for Advanced Prostate Cancer: The PRONOUNCE Trial Study Design

por Melloni, Chiara, Slovin, Susan F., Blemings, Allan, Goodman, Shaun G., Evans, Christopher P., Nilsson, Jan, Bhatt, Deepak L., Zubovskiy, Konstantin, Olesen, Tine K., Dugi, Klaus, Clarke, Noel W., Higano, Celestia S., Roe, Matthew T.
Publicado 2020

Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer

por Barros-Silva, João D., Linn, Douglas E., Steiner, Ivana, Guo, Guoji, Ali, Adnan, Pakula, Hubert, Ashton, Garry, Peset, Isabel, Brown, Michael, Clarke, Noel W., Bronson, Roderick T., Yuan, Guo-Cheng, Orkin, Stuart H., Li, Zhe, Baena, Esther
Publicado 2018

Homologous Recombination Repair Gene Mutation Characterization by Liquid Biopsy: A Phase II Trial of Olaparib and Abiraterone in Metastatic Castrate-Resistant Prostate Cancer

por Carr, T. Hedley, Adelman, Carrie, Barnicle, Alan, Kozarewa, Iwanka, Luke, Sally, Lai, Zhongwu, Hollis, Sally, Dougherty, Brian, Harrington, Elizabeth A., Kang, Jinyu, Saad, Fred, Sala, Nuria, Thiery-Vuillemin, Antoine, Clarke, Noel W., Hodgson, Darren, Barrett, J. Carl
Publicado 2021

Flexible trial design in practice – dropping and adding arms in STAMPEDE: a multi-arm multi-stage randomised controlled trial

por Sydes, Matthew R, James, Nicholas D, Mason, Malcolm D, Clarke, Noel W, Amos, Claire, Anderson, John, de Bono, Johann, Dearnaley, David P, Dwyer, John, Jovic, Gordana, Ritchie, Alastair, Russell, Martin, Sanders, Karen, Thalmann, George, Parmar, Mahesh KB
Publicado 2011

The Automated Bone Scan Index as a Predictor of Response to Prostate Radiotherapy in Men with Newly Diagnosed Metastatic Prostate Cancer: An Exploratory Analysis of STAMPEDE’s “M1|...

por Ali, Adnan, Hoyle, Alex P., Parker, Christopher C., Brawley, Christopher D., Cook, Adrian, Amos, Claire, Calvert, Joanna, Douis, Hassan, Mason, Malcolm D., Attard, Gerhardt, Parmar, Mahesh K.B., Sydes, Matthew R., James, Nicholas D., Clarke, Noel W.
Publicado 2020

Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial

por Sydes, Matthew R, Parmar, Mahesh KB, Mason, Malcolm D, Clarke, Noel W, Amos, Claire, Anderson, John, de Bono, Johann, Dearnaley, David P, Dwyer, John, Green, Charlene, Jovic, Gordana, Ritchie, Alastair WS, Russell, J Martin, Sanders, Karen, Thalmann, George, James, Nicholas D
Publicado 2012

Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the r...

por Langley, Ruth E, Cafferty, Fay H, Alhasso, Abdulla A, Rosen, Stuart D, Sundaram, Subramanian Kanaga, Freeman, Suzanne C, Pollock, Philip, Jinks, Rachel C, Godsland, Ian F, Kockelbergh, Roger, Clarke, Noel W, Kynaston, Howard G, Parmar, Mahesh KB, Abel, Paul D
Publicado 2013

Addition of docetaxel or bisphosphonates to standard of care in men with localised or metastatic, hormone-sensitive prostate cancer: a systematic review and meta-analyses of aggreg...

por Vale, Claire L, Burdett, Sarah, Rydzewska, Larysa H M, Albiges, Laurence, Clarke, Noel W, Fisher, David, Fizazi, Karim, Gravis, Gwenaelle, James, Nicholas D, Mason, Malcolm D, Parmar, Mahesh K B, Sweeney, Christopher J, Sydes, Matthew R, Tombal, Bertrand, Tierney, Jayne F
Publicado 2016

Maintaining bone health by estrogen therapy in patients with advanced prostate cancer: a narrative review

por Coelingh Bennink, Herjan J T, Krijgh, Jan, Egberts, Jan F M, Slootweg, Maria, van Melick, Harm H E, Roos, Erik P M, Somford, Diederik M, Zimmerman, Yvette, Schultz, Iman J, Clarke, Noel W, van Moorselaar, R Jeroen A, Debruyne, Frans M J
Publicado 2022

Adding abiraterone to androgen deprivation therapy in men with metastatic hormone-sensitive prostate cancer: A systematic review and meta-analysis

por Rydzewska, Larysa H.M., Burdett, Sarah, Vale, Claire L., Clarke, Noel W., Fizazi, Karim, Kheoh, Thian, Mason, Malcolm D., Miladinovic, Branko, James, Nicholas D., Parmar, Mahesh K.B., Spears, Melissa R., Sweeney, Christopher J., Sydes, Matthew R., Tran, NamPhuong, Tierney, Jayne F.
Publicado 2017

Association of Bone Metastatic Burden With Survival Benefit From Prostate Radiotherapy in Patients With Newly Diagnosed Metastatic Prostate Cancer: A Secondary Analysis of a Random...

por Ali, Adnan, Hoyle, Alex, Haran, Áine M., Brawley, Christopher D., Cook, Adrian, Amos, Claire, Calvert, Joanna, Douis, Hassan, Mason, Malcolm D., Dearnaley, David, Attard, Gerhardt, Gillessen, Silke, Parmar, Mahesh K. B., Parker, Christopher C., Sydes, Matthew R., James, Nicholas D., Clarke, Noel W.
Publicado 2021

This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols

por Schiavone, Francesca, Bathia, Riya, Letchemanan, Krishna, Masters, Lindsey, Amos, Claire, Bara, Anna, Brown, Louise, Gilson, Clare, Pugh, Cheryl, Atako, Nafisah, Hudson, Fleur, Parmar, Mahesh, Langley, Ruth, Kaplan, Richard S., Parker, Chris, Attard, Gert, Clarke, Noel W., Gillessen, Silke, James, Nicholas D., Maughan, Tim, Sydes, Matthew R.
Publicado 2019