Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance

por Gonzalez de Castro, D, Clarke, P A, Al-Lazikani, B, Workman, P
Publicado 2013

The identification of high and low risk groups for colorectal cancer using rectal mucosal crypt cell production rate (CCPR).

por Rooney, P. S., Clarke, P. A., Gifford, K. A., Hardcastle, J. D., Armitage, N. C.
Publicado 1993

The effect of calcium supplements on rectal mucosal proliferation.

por Armitage, N. C., Rooney, P. S., Gifford, K. A., Clarke, P. A., Hardcastle, J. D.
Publicado 1995

Characterisation of molecular events following cisplatin treatment of two curable ovarian cancer models: contrasting role for p53 induction and apoptosis in vivo

por Clarke, P A, Pestell, K E, Di Stefano, F, Workman, P, Walton, M I
Publicado 2004

Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy.

por Parsons, S. L., Watson, S. A., Collins, H. M., Griffin, N. R., Clarke, P. A., Steele, R. J.
Publicado 1998

Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence

por Watson, S A, Morris, T M, McWilliams, D F, Harris, J, Evans, S, Smith, A, Clarke, P A
Publicado 2002

Bcl-2 expression and response to chemotherapy in colorectal adenocarcinomas.

por Schneider, H. J., Sampson, S. A., Cunningham, D., Norman, A. R., Andreyev, H. J., Tilsed, J. V., Clarke, P. A.
Publicado 1997

Apoptosis is associated with triacylglycerol accumulation in Jurkat T-cells

por Al-Saffar, N M S, Titley, J C, Robertson, D, Clarke, P A, Jackson, L E, Leach, M O, Ronen, S M
Publicado 2002

Progress in the Preclinical Discovery and Clinical Development of Class I and Dual Class I/IV Phosphoinositide 3-Kinase (PI3K) Inhibitors

por Shuttleworth, S.J, Silva, F.A, Cecil, A.R.L, Tomassi, C.D, Hill, T.J, Raynaud, F.I, Clarke, P.A, Workman, P
Publicado 2011

De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis

por El-Zaatari, M, Tobias, A, Grabowska, A M, Kumari, R, Scotting, P J, Kaye, P, Atherton, J, Clarke, P A, Powe, D G, Watson, S A
Publicado 2007

Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis

por Ronen, S M, DiStefano, F, McCoy, C L, Robertson, D, Smith, T A D, Al-Saffar, N M, Titley, J, Cunningham, D C, Griffiths, J R, Leach, M O, Clarke, P A
Publicado 1999

Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control

por Pawlyn, C, Bright, M D, Buros, A F, Stein, C K, Walters, Z, Aronson, L I, Mirabella, F, Jones, J R, Kaiser, M F, Walker, B A, Jackson, G H, Clarke, P A, Bergsagel, P L, Workman, P, Chesi, M, Morgan, G J, Davies, F E
Publicado 2017

Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study

por Andreyev, H J N, Norman, A R, Cunningham, D, Oates, J, Dix, B R, Iacopetta, B J, Young, J, Walsh, T, Ward, R, Hawkins, N, Beranek, M, Jandik, P, Benamouzig, R, Jullian, E, Laurent-Puig, P, Olschwang, S, Muller, O, Hoffmann, I, Rabes, H M, Zietz, C, Troungos, C, Valavanis, C, Yuen, S T, Ho, J W C, Croke, C T, O'Donoghue, D P, Giaretti, W, Rapallo, A, Russo, A, Bazan, V, Tanaka, M, Omura, K, Azuma, T, Ohkusa, T, Fujimori, T, Ono, Y, Pauly, M, Faber, C, Glaesener, R, Goeij, A F P M de, Arends, J W, Andersen, S N, Lövig, T, Breivik, J, Gaudernack, G, Clausen, O P F, Angelis, P De, Meling, G I, Rognum, T O, Smith, R, Goh, H-S, Font, A, Rosell, R, Sun, X F, Zhang, H, Benhattar, J, Losi, L, Lee, J Q, Wang, S T, Clarke, P A, Bell, S, Quirke, P, Bubb, V J, Piris, J, Cruickshank, N R, Morton, D, Fox, J C, Al-Mulla, F, Lees, N, Hall, C N, Snary, D, Wilkinson, K, Dillon, D, Costa, J, Pricolo, V E, Finkelstein, S D, Thebo, J S, Senagore, A J, Halter, S A, Wadler, S, Malik, S, Krtolica, K, Urosevic, N
Publicado 2001