Computational methods to identify novel methyltransferases

por Petrossian, Tanya C, Clarke, Steven G
Publicado 2009

Human protein arginine methyltransferases (PRMTs) can be optimally active under nonphysiological conditions

por Lowe, Troy L., Clarke, Steven G.
Publicado 2022

The Interplay between Protein L-Isoaspartyl Methyltransferase Activity and Insulin-Like Signaling to Extend Lifespan in Caenorhabditis elegans

por Khare, Shilpi, Linster, Carole L., Clarke, Steven G.
Publicado 2011

Correction: The Interplay between Protein L-Isoaspartyl Methyltransferase Activity and Insulin-Like Signaling to Extend Lifespan in Caenorhabditis elegans

por Khare, Shilpi, Linster, Carole L., Clarke, Steven G.
Publicado 2013

The exquisite specificity of human protein arginine methyltransferase 7 (PRMT7) toward Arg-X-Arg sites

por Bondoc, Timothy J., Lowe, Troy L., Clarke, Steven G.
Publicado 2023

Wortmannin Reduces Insulin Signaling and Death in Seizure-Prone Pcmt1(−/−) Mice

por MacKay, Kennen B., Lowenson, Jonathan D., Clarke, Steven G.
Publicado 2012

Methylation of yeast ribosomal protein Rpl3 promotes translational elongation fidelity

por Al-Hadid, Qais, Roy, Kevin, Chanfreau, Guillaume, Clarke, Steven G.
Publicado 2016

Caenorhabditis elegans Battling Starvation Stress: Low Levels of Ethanol Prolong Lifespan in L1 Larvae

por Castro, Paola V., Khare, Shilpi, Young, Brian D., Clarke, Steven G.
Publicado 2012

Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme

por Sherkhanov, Saken, Korman, Tyler P., Clarke, Steven G, Bowie, James U.
Publicado 2016

Circumventing Embryonic Lethality with Lcmt1 Deficiency: Generation of Hypomorphic Lcmt1 Mice with Reduced Protein Phosphatase 2A Methyltransferase Expression and Defects in Insuli...

por MacKay, Kennen B., Tu, Yiping, Young, Stephen G., Clarke, Steven G.
Publicado 2013

The invertebrate Caenorhabditis elegans biosynthesizes ascorbate

por Patananan, Alexander N., Budenholzer, Lauren M., Pedraza, Maria E., Torres, Eric R., Adler, Lital N., Clarke, Steven G.
Publicado 2015

Structure of amyloid-β (20-34) with Alzheimer’s-associated isomerization at Asp23 reveals a distinct protofilament interface

por Warmack, Rebeccah A., Boyer, David R., Zee, Chih-Te, Richards, Logan S., Sawaya, Michael R., Cascio, Duilio, Gonen, Tamir, Eisenberg, David S., Clarke, Steven G.
Publicado 2019

PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145

por Yang, Yanzhong, Hadjikyriacou, Andrea, Xia, Zheng, Gayatri, Sitaram, Kim, Daehoon, Zurita-Lopez, Cecilia, Kelly, Ryan, Guo, Ailan, Li, Wei, Clarke, Steven G., Bedford, Mark T.
Publicado 2015

Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs

por Dhar, Surbhi, Vemulapalli, Vidyasiri, Patananan, Alexander N., Huang, Grace L., Di Lorenzo, Alessandra, Richard, Stephane, Comb, Michael J., Guo, Ailan, Clarke, Steven G., Bedford, Mark T.
Publicado 2013

l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

por Soliman, Remon, Cordero-Maldonado, Maria Lorena, Martins, Teresa G., Moein, Mahsa, Conrotte, Jean-François, Warmack, Rebeccah A., Skupin, Alexander, Crawford, Alexander D., Clarke, Steven G., Linster, Carole L.
Publicado 2021

Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

por Yamamoto, Jun, Inubushi, Sachiko, Han, Qinghong, Tashiro, Yoshihiko, Sugisawa, Norihiko, Hamada, Kazuyuki, Aoki, Yusuke, Miyake, Kentaro, Matsuyama, Ryusei, Bouvet, Michael, Clarke, Steven G., Endo, Itaru, Hoffman, Robert M.
Publicado 2022

Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration...

por Aoki, Yusuke, Han, Qinghong, Tome, Yasunori, Yamamoto, Jun, Kubota, Yutaro, Masaki, Noriyuki, Obara, Koya, Hamada, Kazuyuki, Wang, Justin D., Inubushi, Sachiko, Bouvet, Michael, Clarke, Steven G., Nishida, Kotaro, Hoffman, Robert M.
Publicado 2022

A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis

por Lissina, Elena, Young, Brian, Urbanus, Malene L., Guan, Xue Li, Lowenson, Jonathan, Hoon, Shawn, Baryshnikova, Anastasia, Riezman, Isabelle, Michaut, Magali, Riezman, Howard, Cowen, Leah E., Wenk, Markus R., Clarke, Steven G., Giaever, Guri, Nislow, Corey
Publicado 2011

Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor

por Feoli, Alessandra, Iannelli, Giulia, Cipriano, Alessandra, Milite, Ciro, Shen, Lei, Wang, Zhihao, Hadjikyriacou, Andrea, Lowe, Troy L., Safaeipour, Cyrus, Viviano, Monica, Sarno, Giuliana, Morretta, Elva, Monti, Maria Chiara, Yang, Yanzhong, Clarke, Steven G., Cosconati, Sandro, Castellano, Sabrina, Sbardella, Gianluca
Publicado 2023

Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q

por Ayer, Anita, Fazakerley, Daniel J., Suarna, Cacang, Maghzal, Ghassan J., Sheipouri, Diba, Lee, Kevin J., Bradley, Michelle C., Fernández-del-Rio, Lucía, Tumanov, Sergey, Kong, Stephanie MY., van der Veen, Jelske N., Yang, Andrian, Ho, Joshua W.K., Clarke, Steven G., James, David E., Dawes, Ian W., Vance, Dennis E., Clarke, Catherine F., Jacobs, René L., Stocker, Roland
Publicado 2021