From Concept to Clinical Product: A Brief History of the Novel Shigella Invaplex Vaccine’s Refinement and Evolution

por Turbyfill, K. Ross, Clarkson, Kristen A., Oaks, Edwin V., Kaminski, Robert W.
Publicado 2022

Assembly, Biochemical Characterization, Immunogenicity, Adjuvanticity, and Efficacy of Shigella Artificial Invaplex

por Turbyfill, K. Ross, Clarkson, Kristen A., Vortherms, Anthony R., Oaks, Edwin V., Kaminski, Robert W.
Publicado 2018

Development of the Shigella flexneri 2a, 3a, 6, and S. sonnei artificial Invaplex (Invaplex(AR)) vaccines

por Turbyfill, K. Ross, Clarkson, Kristen A., Oaks, Edwin V., Zurawski, Daniel V., Vortherms, Anthony R., Kaminski, Robert W.
Publicado 2023

Shigella-Specific Immune Profiles Induced after Parenteral Immunization or Oral Challenge with Either Shigella flexneri 2a or Shigella sonnei

por Clarkson, Kristen A., Porter, Chad K., Talaat, Kawsar R., Frenck, Robert W., Alaimo, Cristina, Martin, Patricia, Bourgeois, A. Louis, Kaminski, Robert W.
Publicado 2021

Consensus Report on Shigella Controlled Human Infection Model: Immunological Assays

por Kaminski, Robert W, Pasetti, Marcela F, Aguilar, Ana Older, Clarkson, Kristen A, Rijpkema, Sjoerd, Bourgeois, A Louis, Cohen, Dani, Feavers, Ian, MacLennan, Calman A
Publicado 2019

Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study

por Riddle, Mark S., Kaminski, Robert W., Di Paolo, Claudio, Porter, Chad K., Gutierrez, Ramiro L., Clarkson, Kristen A., Weerts, Hailey E., Duplessis, Christopher, Castellano, Amy, Alaimo, Cristina, Paolino, Kristopher, Gormley, Robert, Gambillara Fonck, Veronica
Publicado 2016

Establishment of a Controlled Human Infection Model with a Lyophilized Strain of Shigella sonnei 53G

por Frenck, Robert W., Dickey, Michelle, Suvarnapunya, Akamol E., Chandrasekaran, Lakshmi, Kaminski, Robert W., Clarkson, Kristen A., McNeal, Monica, Lynen, Amanda, Parker, Susan, Hoeper, Amy, Mani, Sachin, Fix, Alan, Maier, Nicole, Venkatesan, Malabi M., Porter, Chad K.
Publicado 2020

Immune Response Characterization after Controlled Infection with Lyophilized Shigella sonnei 53G

por Clarkson, Kristen A., Frenck, Robert W., Dickey, Michelle, Suvarnapunya, Akamol E., Chandrasekaran, Lakshmi, Weerts, Hailey P., Heaney, Christopher D., McNeal, Monica, Detizio, Kate, Parker, Susan, Hoeper, Amy, Bourgeois, August L., Porter, Chad K., Venkatesan, Malabi M., Kaminski, Robert W.
Publicado 2020

Immune response characterization in a human challenge study with a Shigella flexneri 2a bioconjugate vaccine

por Clarkson, Kristen A., Talaat, Kawsar R., Alaimo, Cristina, Martin, Patricia, Bourgeois, A. Louis, Dreyer, Anita, Porter, Chad K., Chakraborty, Subhra, Brubaker, Jessica, Elwood, Daniel, Frölich, Rahel, DeNearing, Barbara, Weerts, Hailey P., Feijoo, Brittany, Halpern, Jane, Sack, David, Riddle, Mark S., Fonck, Veronica Gambillara, Kaminski, Robert W.
Publicado 2021

Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protection

por Talaat, Kawsar R., Alaimo, Cristina, Martin, Patricia, Bourgeois, A. Louis, Dreyer, Anita M., Kaminski, Robert W., Porter, Chad K., Chakraborty, Subhra, Clarkson, Kristen A., Brubaker, Jessica, Elwood, Daniel, Frölich, Rahel, DeNearing, Barbara, Weerts, Hailey, Feijoo, Brittany L., Halpern, Jane, Sack, David, Riddle, Mark S., Fonck, Veronica Gambillara
Publicado 2021

Efficacy, safety, and immunogenicity of the Shigella sonnei 1790GAHB GMMA candidate vaccine: Results from a phase 2b randomized, placebo-controlled challenge study in adults

por Frenck, Robert W., Conti, Valentino, Ferruzzi, Pietro, Ndiaye, Augustin G.W., Parker, Susan, McNeal, Monica Malone, Dickey, Michelle, Granada, Juan Paolo, Cilio, Giulia Luna, De Ryck, Iris, Necchi, Francesca, Suvarnapunya, Akamol E., Rossi, Omar, Acquaviva, Alessandra, Chandrasekaran, Lakshmi, Clarkson, Kristen A., Auerbach, Joachim, Marchetti, Elisa, Kaminski, Robert W., Micoli, Francesca, Rappuoli, Rino, Saul, Allan, Martin, Laura B., Podda, Audino
Publicado 2021