Rapid, Directed Differentiation of Retinal Pigment Epithelial Cells from Human Embryonic or Induced Pluripotent Stem Cells

por Foltz, Leah P., Clegg, Dennis O.
Publicado 2017

MUC1* Mediates the Growth of Human Pluripotent Stem Cells

por Hikita, Sherry T., Kosik, Kenneth S., Clegg, Dennis O., Bamdad, Cynthia
Publicado 2008

Cellular models and therapies for age-related macular degeneration

por Forest, David L., Johnson, Lincoln V., Clegg, Dennis O.
Publicado 2015

ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell–Derived Retinal Pigmented Epithelium

por Croze, Roxanne H., Thi, William J., Clegg, Dennis O.
Publicado 2016

Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9

por Foltz, Leah P., Howden, Sara E., Thomson, James A., Clegg, Dennis O.
Publicado 2018

Cell-mediated remodeling of biomimetic encapsulating hydrogels triggered by adipogenic differentiation of adipose stem cells

por Clevenger, Tracy N, Luna, Gabriel, Boctor, Daniel, Fisher, Steven K, Clegg, Dennis O
Publicado 2016

Determining the optimal stage for cryopreservation of human embryonic stem cell-derived retinal pigment epithelial cells

por Zhang, Ting, Huang, Xianyu, Liu, Sujun, Bai, Xinyue, Zhu, Xinyue, Clegg, Dennis O., Jiang, Mei, Sun, Xiaodong
Publicado 2022

Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models

por Lin, Tai-Chi, Seiler, Magdalene J., Zhu, Danhong, Falabella, Paulo, Hinton, David R., Clegg, Dennis O., Humayun, Mark S., Thomas, Biju B.
Publicado 2017

Plasma metabolomics supports non-fasted sampling for metabolic profiling across a spectrum of glucose tolerance in the Nile rat model for type 2 diabetes

por Anderson, Benton J., Curtis, Anne M., Jen, Annie, Thomson, James A., Clegg, Dennis O., Jiang, Peng, Coon, Joshua J., Overmyer, Katherine A., Toh, Huishi
Publicado 2023

Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report

por Fortress, Ashley M., Miyagishima, Kiyoharu J., Reed, Amberlynn A., Temple, Sally, Clegg, Dennis O., Tucker, Budd A., Blenkinsop, Timothy A., Harb, George, Greenwell, Thomas N., Ludwig, Tenneille E., Bharti, Kapil
Publicado 2023

HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells

por Gornalusse, Germán G., Hirata, Roli K., Funk, Sarah, Riolobos, Laura, Lopes, Vanda S., Manske, Gabriel, Prunkard, Donna, Colunga, Aric G., Hanafi, Laïla-Aïcha, Clegg, Dennis O., Turtle, Cameron, Russell, David W.
Publicado 2017

Vascular changes in diabetic retinopathy – A longitudinal study in the Nile rat

por Toh, Huishi, Smolentsev, Alexander, Bozadjian, Rachel V., Keeley, Patrick W., Lockwood, Madison D., Sadjadi, Ryan, Clegg, Dennis O., Blodi, Barbara A., Coffey, Peter J., Reese, Benjamin E., Thomson, James A.
Publicado 2019

Microcarrier-Based Culture of Human Pluripotent Stem-Cell-Derived Retinal Pigmented Epithelium

por Faynus, Mohamed A., Bailey, Jeffrey K., Pennington, Britney O., Katsura, Mika, Proctor, Duncan A., Yeh, Ashley K., Menon, Sneha, Choi, Dylan G., Lebkowski, Jane S., Johnson, Lincoln V., Clegg, Dennis O.
Publicado 2022

Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat

por Carr, Amanda-Jayne, Vugler, Anthony A., Hikita, Sherry T., Lawrence, Jean M., Gias, Carlos, Chen, Li Li, Buchholz, David E., Ahmado, Ahmad, Semo, Ma'ayan, Smart, Matthew J. K., Hasan, Shazeen, da Cruz, Lyndon, Johnson, Lincoln V., Clegg, Dennis O., Coffey, Pete J.
Publicado 2009

Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo

por Pennington, Britney O., Bailey, Jeffrey K., Faynus, Mohamed A., Hinman, Cassidy, Hee, Mitchell N., Ritts, Rory, Nadar, Vignesh, Zhu, Danhong, Mitra, Debbie, Martinez-Camarillo, Juan Carlos, Lin, Tai-Chi, Thomas, Biju B., Hinton, David R., Humayun, Mark S., Lebkowski, Jane, Johnson, Lincoln V., Clegg, Dennis O.
Publicado 2021

One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration

por Kashani, Amir H., Lebkowski, Jane S., Rahhal, Firas M., Avery, Robert L., Salehi-Had, Hani, Chen, Sanford, Chan, Clement, Palejwala, Neal, Ingram, April, Dang, Wei, Lin, Chih-Min, Mitra, Debbie, Pennington, Britney O., Hinman, Cassidy, Faynus, Mohamed A., Bailey, Jeffrey K., Mohan, Sukriti, Rao, Narsing, Johnson, Lincoln V., Clegg, Dennis O., Hinton, David R., Humayun, Mark S.
Publicado 2021

Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration

por Kashani, Amir H., Lebkowski, Jane S., Hinton, David R., Zhu, Danhong, Faynus, Mohamed A., Chen, Sanford, Rahhal, Firas M., Avery, Robert L., Salehi-Had, Hani, Chan, Clement, Palejwala, Neal, Ingram, April, Dang, Wei, Lin, Chih-Min, Mitra, Debbie, Martinez-Camarillo, Juan Carlos, Bailey, Jeff, Arnold, Cassidy, Pennington, Britney O., Rao, Narsing, Johnson, Lincoln V., Clegg, Dennis O., Humayun, Mark S.
Publicado 2022

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes

por Toh, Huishi, Yang, Chentao, Formenti, Giulio, Raja, Kalpana, Yan, Lily, Tracey, Alan, Chow, William, Howe, Kerstin, Bergeron, Lucie A., Zhang, Guojie, Haase, Bettina, Mountcastle, Jacquelyn, Fedrigo, Olivier, Fogg, John, Kirilenko, Bogdan, Munegowda, Chetan, Hiller, Michael, Jain, Aashish, Kihara, Daisuke, Rhie, Arang, Phillippy, Adam M., Swanson, Scott A., Jiang, Peng, Clegg, Dennis O., Jarvis, Erich D., Thomson, James A., Stewart, Ron, Chaisson, Mark J. P., Bukhman, Yury V.
Publicado 2022