Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells

por Conroy, Lindsey R., Lorkiewicz, Pawel, He, Liqing, Yin, Xinmin, Zhang, Xiang, Rai, Shesh N., Clem, Brian F.
Publicado 2020

Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation

por Telang, Sucheta, Clem, Brian F, Klarer, Alden C, Clem, Amy L, Trent, John O, Bucala, Richard, Chesney, Jason
Publicado 2012

A Novel Small Molecule Antagonist of Choline Kinase-α That Simultaneously Suppresses MAPK and PI3K/AKT Signaling

por Clem, Brian F., Clem, Amy L., Yalcin, Abdullah, Goswami, Umesh, Arumugam, Sengodagounder, Telang, Sucheta, Trent, John O., Chesney, Jason
Publicado 2011

Expression of the lncRNA Maternally Expressed Gene 3 (MEG3) Contributes to the Control of Lung Cancer Cell Proliferation by the Rb Pathway

por Kruer, Traci L., Dougherty, Susan M., Reynolds, Lindsey, Long, Elizabeth, de Silva, Tanya, Lockwood, William W., Clem, Brian F.
Publicado 2016

Control of Glutamine Metabolism By the Tumor Suppressor Rb

por Reynolds, Miriam R., Lane, Andrew N., Robertson, Brian, Kemp, Sharen, Liu, Yongqing, Hill, Bradford G., Dean, Douglas C., Clem, Brian F.
Publicado 2013

Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation

por Lorkiewicz, Pawel K., Gibb, Andrew A., Rood, Benjamin R., He, Liqing, Zheng, Yuting, Clem, Brian F., Zhang, Xiang, Hill, Bradford G.
Publicado 2019

Nuclear Pyruvate Kinase M2 (PKM2) Contributes to Phosphoserine Aminotransferase 1 (PSAT1)-Mediated Cell Migration in EGFR-Activated Lung Cancer Cells

por Biyik-Sit, Rumeysa, Kruer, Traci, Dougherty, Susan, Bradley, James A., Wilkey, Daniel W., Merchant, Michael L., Trent, John O., Clem, Brian F.
Publicado 2021

Targeting aspartate aminotransferase in breast cancer

por Thornburg, Joshua Marshall, Nelson, Kristin K, Clem, Brian F, Lane, Andrew N, Arumugam, Sengodagounder, Simmons, Allan, Eaton, John W, Telang, Sucheta, Chesney, Jason
Publicado 2008

Cytochrome c oxidase is activated by the oncoprotein Ras and is required for A549 lung adenocarcinoma growth

por Telang, Sucheta, Nelson, Kristin K, Siow, Deanna L, Yalcin, Abdullah, Thornburg, Joshua M, Imbert-Fernandez, Yoannis, Klarer, Alden C, Farghaly, Hanan, Clem, Brian F, Eaton, John W, Chesney, Jason
Publicado 2012

Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo

por Conroy, Lindsey R., Dougherty, Susan, Kruer, Traci, Metcalf, Stephanie, Lorkiewicz, Pawel, He, Liqing, Yin, Xinmin, Zhang, Xiang, Arumugam, Sengodagounder, Young, Lyndsay E.A., Sun, Ramon C., Clem, Brian F.
Publicado 2020

Phase II trial of the regulatory T cell-depleting agent, denileukin diftitox, in patients with unresectable stage IV melanoma

por Telang, Sucheta, Rasku, Mary Ann, Clem, Amy L, Carter, Karen, Klarer, Alden C, Badger, Wesley R, Milam, Rebecca A, Rai, Shesh N, Pan, Jianmin, Gragg, Hana, Clem, Brian F, McMasters, Kelly M, Miller, Donald M, Chesney, Jason
Publicado 2011

Lactate supports a metabolic-epigenetic link in macrophage polarization

por Noe, Jordan T., Rendon, Beatriz E., Geller, Anne E., Conroy, Lindsey R., Morrissey, Samantha M., Young, Lyndsay E.A., Bruntz, Ronald C., Kim, Eun J., Wise-Mitchell, Ashley, Barbosa de Souza Rizzo, Mariana, Relich, Eric R., Baby, Becca V., Johnson, Lance A., Affronti, Hayley C., McMasters, Kelly M., Clem, Brian F., Gentry, Matthew S., Yan, Jun, Wellen, Kathryn E., Sun, Ramon C., Mitchell, Robert A.
Publicado 2021