AmpUMI: design and analysis of unique molecular identifiers for deep amplicon sequencing

por Clement, Kendell, Farouni, Rick, Bauer, Daniel E, Pinello, Luca
Publicado 2018

Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer

por Smith, Zachary D., Shi, Jiantao, Gu, Hongcang, Donaghey, Julie, Clement, Kendell, Cacciarelli, Davide, Gnirke, Andreas, Michor, Franziska, Meissner, Alexander
Publicado 2017

Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing

por ten Hacken, Elisa, Gruber, Michaela, Hernández-Sánchez, María, Hoffmann, Gabriela Brunsting, Baranowski, Kaitlyn, Redd, Robert A., Clement, Kendell, Livak, Kenneth, Wu, Catherine J.
Publicado 2023

Assessment of computational methods for the analysis of single-cell ATAC-seq data

por Chen, Huidong, Lareau, Caleb, Andreani, Tommaso, Vinyard, Michael E., Garcia, Sara P., Clement, Kendell, Andrade-Navarro, Miguel A., Buenrostro, Jason D., Pinello, Luca
Publicado 2019

Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling

por Boyle, Patrick, Clement, Kendell, Gu, Hongcang, Smith, Zachary D, Ziller, Michael, Fostel, Jennifer L, Holmes, Laurie, Meldrim, Jim, Kelley, Fontina, Gnirke, Andreas, Meissner, Alexander
Publicado 2012

Targets and genomic constraints of ectopic Dnmt3b expression

por Zhang, Yingying, Charlton, Jocelyn, Karnik, Rahul, Beerman, Isabel, Smith, Zachary D, Gu, Hongcang, Boyle, Patrick, Mi, Xiaoli, Clement, Kendell, Pop, Ramona, Gnirke, Andreas, Rossi, Derrick J, Meissner, Alexander
Publicado 2018

Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models

por Hacken, Elisa ten, Yin, Shanye, Redd, Robert, Sánchez, María Hernández, Clement, Kendell, Hoffmann, Gabriela Brunsting, Regis, Fara F., Witten, Elizabeth, Li, Shuqiang, Neuberg, Donna, Pinello, Luca, Livak, Kenneth J., Wu, Catherine J.
Publicado 2022

A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs

por Choi, Jiho, Lee, Soohyun, Clement, Kendell, Mallard, William, Tagliazucchi, Guidantonio Malagoli, Lim, Hotae, Choi, In Young, Ferrari, Francesco, Tsankov, Alex, Pop, Ramona, Lee, Gabsang, Rinn, John, Meissner, Alexander, Park, Peter J., Hochedlinger, Konrad
Publicado 2015

Global delay in nascent strand DNA methylation

por Charlton, Jocelyn, Downing, Timothy L., Smith, Zachary D., Gu, Hongcang, Clement, Kendell, Pop, Ramona, Akopian, Veronika, Klages, Sven, Santos, David P., Tsankov, Alexander M., Timmermann, Bernd, Ziller, Michael J., Kiskinis, Evangelos, Gnirke, Andreas, Meissner, Alexander
Publicado 2018

Epigenomics and chromatin dynamics

por Akopian, Veronika, Chan, Michelle M, Clement, Kendell, Galonska, Christina, Gifford, Casey A, Lehtola, Elizabeth, Liao, Jing, Samavarchi-Tehrani, Payman, Sindhu, Camille, Smith, Zachary D, Tsankov, Alexander M, Webster, Jamie, Zhang, Yingying, Ziller, Michael J, Meissner, Alexander
Publicado 2012

Age- and Pregnancy-Associated DNA Methylation Changes in Mammary Epithelial Cells

por Huh, Sung Jin, Clement, Kendell, Jee, David, Merlini, Alessandra, Choudhury, Sibgat, Maruyama, Reo, Yoo, Ronnie, Chytil, Anna, Boyle, Patrick, Ran, Fei Ann, Moses, Harold L., Barcellos-Hoff, Mary Helen, Jackson-Grusby, Laurie, Meissner, Alexander, Polyak, Kornelia
Publicado 2015

CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells

por Petri, Karl, Zhang, Weiting, Ma, Junyan, Schmidts, Andrea, Lee, Hyunho, Horng, Joy E., Kim, Daniel Y., Kurt, Ibrahim C., Clement, Kendell, Hsu, Jonathan Y., Pinello, Luca, Maus, Marcela V., Joung, J. Keith, Yeh, Jing-Ruey Joanna
Publicado 2022

Genome-wide tracking of dCas9-methyltransferase footprints

por Galonska, Christina, Charlton, Jocelyn, Mattei, Alexandra L., Donaghey, Julie, Clement, Kendell, Gu, Hongcang, Mohammad, Arman W., Stamenova, Elena K., Cacchiarelli, Davide, Klages, Sven, Timmermann, Bernd, Cantz, Tobias, Schöler, Hans R., Gnirke, Andreas, Ziller, Michael J., Meissner, Alexander
Publicado 2018

High throughput single-cell detection of multiplex CRISPR-edited gene modifications

por ten Hacken, Elisa, Clement, Kendell, Li, Shuqiang, Hernández-Sánchez, María, Redd, Robert, Wang, Shu, Ruff, David, Gruber, Michaela, Baranowski, Kaitlyn, Jacob, Jose, Flynn, James, Jones, Keith W., Neuberg, Donna, Livak, Kenneth J., Pinello, Luca, Wu, Catherine J.
Publicado 2020

Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

por Kleinstiver, Benjamin P., Sousa, Alexander A., Walton, Russell T., Tak, Y. Esther, Hsu, Jonathan Y., Clement, Kendell, Welch, Moira M., Horng, Joy E., Malagon-Lopez, Jose, Scarfò, Irene, Maus, Marcela V., Pinello, Luca, Aryee, Martin J., Joung, J. Keith
Publicado 2019

Reduced MEK inhibition preserves genomic stability in naïve human ES cells

por Stefano, Bruno Di, Ueda, Mai, Sabri, Shan, Brumbaugh, Justin, Huebner, Aaron J., Sahakyan, Anna, Clement, Kendell, Clowers, Katie J., Erickson, Alison R., Shioda, Keiko, Gygi, Steven P., Gu, Hongcang, Shioda, Toshi, Meissner, Alexander, Takashima, Yasuhiro, Plath, Kathrin, Hochedlinger, Konrad
Publicado 2018

Genetic determinants and epigenetic effects of pioneer factor occupancy

por Donaghey, Julie, Thakurela, Sudhir, Charlton, Jocelyn, Chen, Jennifer, Smith, Zachary D., Gu, Hongcang, Pop, Ramona, Clement, Kendell, Stamenova, Elena, Karnik, Rahul, Kelley, David R., Gifford, Casey A., Cacchiarelli, Davide, Rinn, John L., Gnirke, Andreas, Ziller, Michael J., Meissner, Alexander
Publicado 2018

A Code of Ethics for Gene Drive Research

por Annas, George J., Beisel, Chase L., Clement, Kendell, Crisanti, Andrea, Francis, Stacy, Galardini, Marco, Galizi, Roberto, Grünewald, Julian, Immobile, Greta, Khalil, Ahmad S., Müller, Ruth, Pattanayak, Vikram, Petri, Karl, Paul, Ligi, Pinello, Luca, Simoni, Alekos, Taxiarchi, Chrysanthi, Joung, J. Keith
Publicado 2021

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells

por Liao, Jing, Karnik, Rahul, Gu, Hongcang, Ziller, Michael J., Clement, Kendell, Tsankov, Alexander M., Akopian, Veronika, Gifford, Casey A., Donaghey, Julie, Galonska, Christina, Pop, Ramona, Reyon, Deepak, Tsai, Shengdar Q., Mallard, William, Joung, J. Keith, Rinn, John L., Gnirke, Andreas, Meissner, Alexander
Publicado 2015

In vivo CRISPR editing with no detectable genome-wide off-target mutations

por Akcakaya, Pinar, Bobbin, Maggie L., Guo, Jimmy A., Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P., Fellows, Mick D., Porritt, Michelle J., Firth, Mike A., Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q., Nguyen, Nhu T., Nitsch, Roberto, Mayr, Lorenz M., Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J., Maresca, Marcello, Joung, J. Keith
Publicado 2018