Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastroesophageal junction

por Clemons, Nicholas J, Phillips, Wayne A, Lord, Reginald V
Publicado 2013

Opportunities for Ferroptosis in Cancer Therapy

por Fujihara, Kenji M., Zhang, Bonnie Z., Clemons, Nicholas J.
Publicado 2021

Inhibiting system x(C)(−) and glutathione biosynthesis – a potential Achilles' heel in mutant-p53 cancers

por Clemons, Nicholas J., Liu, David S., Duong, Cuong P., Phillips, Wayne A.
Publicado 2017

ASO Author Reflections: Are Tumor-Infiltrating Neutrophils Drivers of Metastatic Disease in Esophageal Cancer Patients Treated with Neoadjuvant Therapy?

por Cabalag, Carlos S., Phillips, Wayne A., Duong, Cuong P., Clemons, Nicholas J.
Publicado 2022

The prognostic value of TP53 mutations in oesophageal adenocarcinoma: a systematic review and meta-analysis

por Fisher, Oliver M, Lord, Sarah J, Falkenback, Dan, Clemons, Nicholas J, Eslick, Guy D, Lord, Reginald V
Publicado 2017

Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation

por Milne, Julia V., Zhang, Bonnie Z., Fujihara, Kenji M., Dawar, Swati, Phillips, Wayne A., Clemons, Nicholas J.
Publicado 2021

Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis

por Liu, David S., Hoefnagel, Sanne J.M., Fisher, Oliver M., Krishnadath, Kausilia K., Montgomery, Karen G., Busuttil, Rita A., Colebatch, Andrew J., Read, Matthew, Duong, Cuong P., Phillips, Wayne A., Clemons, Nicholas J.
Publicado 2016

GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma

por Gotovac, Jovana R, Liu, David SH, Yates, Michael J, Milne, Julia V, Macpherson, Arthi A, Simpson, Kaylene J, Eslick, Guy D, Mitchell, Catherine, Duong, Cuong P, Phillips, Wayne A, Clemons, Nicholas J
Publicado 2020

The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism

por Jackson, Thomas D., Hock, Daniella H., Fujihara, Kenji M., Palmer, Catherine S., Frazier, Ann E., Low, Yau C., Kang, Yilin, Ang, Ching-Seng, Clemons, Nicholas J., Thorburn, David R., Stroud, David A., Stojanovski, Diana
Publicado 2021

Loss of SMAD4 Is Sufficient to Promote Tumorigenesis in a Model of Dysplastic Barrett’s Esophagus

por Gotovac, Jovana R., Kader, Tanjina, Milne, Julia V., Fujihara, Kenji M., Lara-Gonzalez, Luis E., Gorringe, Kylie L., Kalimuthu, Sangeetha N., Jayawardana, Madawa W., Duong, Cuong P., Phillips, Wayne A., Clemons, Nicholas J.
Publicado 2021

Potential Clinical Utility of a Targeted Circulating Tumor DNA Assay in Esophageal Adenocarcinoma

por Cabalag, Carlos S., Yates, Michael, Corrales, Mariana Benitez, Yeh, Paul, Wong, Stephen Q., Zhang, Bonnie Z., Fujihara, Kenji M., Chong, Lynn, Hii, Michael W., Dawson, Sarah-Jane, Phillips, Wayne A., Duong, Cuong P., Clemons, Nicholas J.
Publicado 2022

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

por Ceder, Sophia, Eriksson, Sofi E., Liang, Ying Yu, Cheteh, Emarndeena H., Zhang, Si Min, Fujihara, Kenji M., Bianchi, Julie, Bykov, Vladimir J. N., Abrahmsen, Lars, Clemons, Nicholas J., Nordlund, Pär, Rudd, Sean G., Wiman, Klas G.
Publicado 2021

Multiparametric High-Content Cell Painting Identifies Copper Ionophores as Selective Modulators of Esophageal Cancer Phenotypes

por Hughes, Rebecca E., Elliott, Richard J. R., Li, Xiaodun, Munro, Alison F., Makda, Ashraff, Carter, Roderick N., Morton, Nicholas M., Fujihara, Kenji, Clemons, Nicholas J., Fitzgerald, Rebecca, O’Neill, J. Robert, Hupp, Ted, Carragher, Neil O.
Publicado 2022

Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

por Ceder, Sophia, Eriksson, Sofi E., Liang, Ying Yu, Cheteh, Emarndeena H., Zhang, Si Min, Fujihara, Kenji M., Bianchi, Julie, Bykov, Vladimir J. N., Abrahmsen, Lars, Clemons, Nicholas J., Nordlund, Pär, Rudd, Sean G., Wiman, Klas G.
Publicado 2022

Mutant p53 Mediates Sensitivity to Cancer Treatment Agents in Oesophageal Adenocarcinoma Associated with MicroRNA and SLC7A11 Expression

por Eichelmann, Ann-Kathrin, Mayne, George C., Chiam, Karen, Due, Steven L., Bastian, Isabell, Butz, Frederike, Wang, Tingting, Sykes, Pamela J., Clemons, Nicholas J., Liu, David S., Michael, Michael Z., Karapetis, Christos S., Hummel, Richard, Watson, David I., Hussey, Damian J.
Publicado 2021

Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

por Kang, Yilin, Anderson, Alexander J, Jackson, Thomas Daniel, Palmer, Catherine S, De Souza, David P, Fujihara, Kenji M, Stait, Tegan, Frazier, Ann E, Clemons, Nicholas J, Tull, Deidreia, Thorburn, David R, McConville, Malcolm J, Ryan, Michael T, Stroud, David A, Stojanovski, Diana
Publicado 2019

Correction: Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

por Kang, Yilin, Anderson, Alexander J, Jackson, Thomas Daniel, Palmer, Catherine S, De Souza, David P, Fujihara, Kenji M, Stait, Tegan, Frazier, Ann E, Clemons, Nicholas J, Tull, Deidreia, Thorburn, David R, McConville, Malcolm J, Ryan, Michael T, Stroud, David A, Stojanovski, Diana
Publicado 2020

A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death

por Ceder, Sophia, Eriksson, Sofi E, Cheteh, Emarndeena H, Dawar, Swati, Corrales Benitez, Mariana, Bykov, Vladimir J N, Fujihara, Kenji M, Grandin, Mélodie, Li, Xiaodun, Ramm, Susanne, Behrenbruch, Corina, Simpson, Kaylene J, Hollande, Frédéric, Abrahmsen, Lars, Clemons, Nicholas J, Wiman, Klas G
Publicado 2020

Inhibiting the system x(C)(−)/glutathione axis selectively targets cancers with mutant-p53 accumulation

por Liu, David S., Duong, Cuong P., Haupt, Sue, Montgomery, Karen G., House, Colin M., Azar, Walid J., Pearson, Helen B., Fisher, Oliver M., Read, Matthew, Guerra, Glen R., Haupt, Ygal, Cullinane, Carleen, Wiman, Klas G., Abrahmsen, Lars, Phillips, Wayne A., Clemons, Nicholas J.
Publicado 2017

Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid‐induced DNA damage

por Molendijk, Jeffrey, Kolka, Cathryn M., Cairns, Henry, Brosda, Sandra, Mohamed, Ahmed, Shah, Alok K., Brown, Ian, Hodson, Mark P., Hennessy, Thomas, Liu, Guanghao, Stoll, Thomas, Richards, Renee S., Gartside, Michael, Patel, Kalpana, Clemons, Nicholas J., Phillips, Wayne A., Barbour, Andrew, Westerhuis, Johan A., Hill, Michelle M.
Publicado 2022