Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI

por Nicolson, Phillip L.R., Hughes, Craig E., Watson, Stephanie, Nock, Sophie H., Hardy, Alexander T., Watson, Callum N., Montague, Samantha J., Clifford, Hayley, Huissoon, Aarnoud P., Malcor, Jean-Daniel, Thomas, Mark R., Pollitt, Alice Y., Tomlinson, Michael G., Pratt, Guy, Watson, Steve P.
Publicado 2018

Low-dose Btk inhibitors selectively block platelet activation by CLEC-2

por Nicolson, Phillip L.R., Nock, Sophie H., Hinds, Joshua, Garcia-Quintanilla, Lourdes, Smith, Christopher W., Campos, Joana, Brill, Alexander, Pike, Jeremy A., Khan, Abdullah O., Poulter, Natalie S., Kavanagh, Deidre M., Watson, Stephanie, Watson, Callum N., Clifford, Hayley, Huissoon, Aarnoud P., Pollitt, Alice Y., Eble, Johannes A., Pratt, Guy, Watson, Steve P., Hughes, Craig E.
Publicado 2020