mTOR signaling in glioblastoma: lessons learned from bench to bedside

por Akhavan, David, Cloughesy, Timothy F., Mischel, Paul S.
Publicado 2010

Modified Criteria for Radiographic Response Assessment in Glioblastoma Clinical Trials

por Ellingson, Benjamin M., Wen, Patrick Y., Cloughesy, Timothy F.
Publicado 2017

Radiographic Response Assessment Strategies for Early-Phase Brain Trials in Complex Tumor Types and Drug Combinations: from Digital “Flipbooks” to Control Systems Theory

por Ellingson, Benjamin M., Levin, Victor A., Cloughesy, Timothy F.
Publicado 2022

Arsenic reverses glioblastoma resistance to mTOR-targeted therapies

por Iwanami, Akio, Cloughesy, Timothy F., Cavenee, Webster K., Mischel, Paul S.
Publicado 2013

Longitudinal Patterns in Clinical and Imaging Measurements Predict Residual Survival in Glioblastoma Patients

por Smedley, Nova F., Ellingson, Benjamin M., Cloughesy, Timothy F., Hsu, William
Publicado 2018

Update and developments in the treatment of glioblastoma multiforme – focus on bevacizumab

por Wagle, Naveed, Nghiemphu, Leia, Lai, Albert, Pope, Whitney, Mischel, Paul S, Cloughesy, Timothy
Publicado 2010

A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas

por Nghiemphu, Phioanh Leia, Lai, Albert, Green, Richard M., Reardon, David A., Cloughesy, Timothy
Publicado 2012

Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance

por Wu, Si-Han, Bi, Jun-Feng, Cloughesy, Timothy, Cavenee, Webster K., Mischel, Paul S.
Publicado 2014

The Future Glioblastoma Clinical Trials Landscape: Early Phase 0, Window of Opportunity, and Adaptive Phase I–III Studies

por Cho, Nicholas S., Wong, Weng Kee, Nghiemphu, Phioanh L., Cloughesy, Timothy F., Ellingson, Benjamin M.
Publicado 2023

Response Assessment Criteria for Glioblastoma: Practical Adaptation and Implementation in Clinical Trials of Antiangiogenic Therapy

por Chinot, Olivier L., Macdonald, David R., Abrey, Lauren E., Zahlmann, Gudrun, Kerloëguen, Yannick, Cloughesy, Timothy F.
Publicado 2013

DIPG-55. DIRECT BRAIN-TO-BRAIN WORKFLOW ENABLES THE PRECLINICAL MODELING OF PEDIATRIC GLIOMAS

por Tum, Hong, Tse, Christopher, Salinas, Jennifer, Bayley, Nicholas, Zhu, Henan, Cloughesy, Timothy, Liau, Linda, Graeber, Thomas, Nathanson, David
Publicado 2023

In Silico Enhanced Restriction Enzyme Based Methylation Analysis of the Human Glioblastoma Genome Using Agilent 244K CpG Island Microarrays

por Tran, Anh, Escovedo, Cameron, Migdall-Wilson, Justine, Chou, Arthur P., Chen, Weidong, Cloughesy, Timothy, Nelson, Stanley, Lai, Albert
Publicado 2010

MRI Radiomic Features to Predict IDH1 Mutation Status in Gliomas: A Machine Learning Approach using Gradient Tree Boosting

por Sakai, Yu, Yang, Chen, Kihira, Shingo, Tsankova, Nadejda, Khan, Fahad, Hormigo, Adilia, Lai, Albert, Cloughesy, Timothy, Nael, Kambiz
Publicado 2020

DDRE-23. A COMPREHENSIVE CHARACTERIZATION OF THE GBM LIPIDOME REVEALS A MOLECULARLY-DEFINED SUB-GROUP WITH HEIGHTENED SENSITIVITY TO LIPID PEROXIDATION INDUCED CELL DEATH

por Morrow, Danielle, Minami, Jenna, Bayley, Nicholas, Williams, Kevin, Bensinger, Steven, Prins, Robert, Liau, Linda, Cloughesy, Timothy, Nathanson, David
Publicado 2021

DIPG-56. PEDIATRIC GLIOMAS EXHIBIT A UNIQUE LIPID METABOLIC PHENOTYPE DISTINCT FROM ADULT GBMS

por Salinas, Jennifer, Minami, Jenna, Bayley, Nicholas, Tse, Christopher, Zhu, Henan, Tum, Hong, Cloughesy, Timothy, Liau, Linda, Graber, Thomas, Nathanson, David
Publicado 2023

SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells

por Geng, Feng, Zhong, Yaogang, Su, Huali, Lefai, Etienne, Magaki, Shino, Cloughesy, Timothy F., Yong, William H., Chakravarti, Arnab, Guo, Deliang
Publicado 2023

Lipid Droplets Maintain Energy Homeostasis and Glioblastoma Growth via Autophagic Release of Stored Fatty Acids

por Wu, Xiaoning, Geng, Feng, Cheng, Xiang, Guo, Qiang, Zhong, Yaogang, Cloughesy, Timothy F., Yong, William H., Chakravarti, Arnab, Guo, Deliang
Publicado 2020

THER-06. THERAPEUTIC EFFICACY OF RRV-MEDIATED PRODRUG ACTIVATOR GENE THERAPY IN CLINICAL TRIALS OF RECURRENT HIGH-GRADE GLIOMA AND IN MURINE ORTHOTOPIC MODELS OF INTRACEREBRAL GLIO...

por Richardson, Angela, Collins, Sara, Inagaki, Akihito, Armstrong, Valerie, Robbins, David, Ayad, Nagi, Gruber, Harry, Jolly, Douglas, Cloughesy, Timothy, Kasahara, Noriyuki
Publicado 2020

ETMM-02. PRECLINICAL MODELS REVEAL BRAIN-MICROENVIRONMENT SPECIFIC METABOLIC DEPENDENCIES IN GLIOBLASTOMA

por Minami, Jenna, Bayley, Nicholas, Tse, Christopher, Zhu, Henan, Morrow, Danielle, Yong, William, Liau, Linda, Cloughesy, Timothy F, Graeber, Thomas, Nathanson, David A
Publicado 2021

Association between lesion location and language function in adult glioma using voxel-based lesion-symptom mapping

por Banerjee, Pia, Leu, Kevin, Harris, Robert J., Cloughesy, Timothy F., Lai, Albert, Nghiemphu, Phioanh L., Pope, Whitney B., Bookheimer, Susan Y., Ellingson, Benjamin M.
Publicado 2015