Navigating the ERK1/2 MAPK Cascade

por Martin-Vega, Ana, Cobb, Melanie H.
Publicado 2023

WNK pathways in cancer signaling networks

por Gallolu Kankanamalage, Sachith, Karra, Aroon S., Cobb, Melanie H.
Publicado 2018

WNK1 in Malignant Behaviors: A Potential Target for Cancer?

por Jung, Ji-Ung, Jaykumar, Ankita B., Cobb, Melanie H.
Publicado 2022

Thiostrepton inhibits stable 70S ribosome binding and ribosome-dependent GTPase activation of elongation factor G and elongation factor 4

por Walter, Justin D., Hunter, Margaret, Cobb, Melanie, Traeger, Geoff, Spiegel, P. Clint
Publicado 2012

Sucralose activates an ERK1/2–ribosomal protein S6 signaling axis

por Guerra, Marcy L., Kalwat, Michael A., McGlynn, Kathleen, Cobb, Melanie H.
Publicado 2017

α(2)-Adrenergic Disruption of β Cell BDNF-TrkB Receptor Tyrosine Kinase Signaling

por Kalwat, Michael A., Huang, Zhimin, Binns, Derk D., McGlynn, Kathleen, Cobb, Melanie H.
Publicado 2020

The Pancreatic ß-cell Response to Secretory Demands and Adaption to Stress

por Kalwat, Michael A, Scheuner, Donalyn, Rodrigues-dos-Santos, Karina, Eizirik, Decio L, Cobb, Melanie H
Publicado 2021

Modulating p38 MAPK signaling by proteostasis mechanisms supports tissue integrity during growth and aging

por Yuan, Wang, Weaver, Yi M., Earnest, Svetlana, Taylor, Clinton A., Cobb, Melanie H., Weaver, Benjamin P.
Publicado 2023

Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched

por Reed, Xylena, Cobb, Melanie M., Skinbinski, Gaia, Roosen, Dorien, Kaganovich, Alice, Ding, Jinhui, Finkbeiner, Steve, Cookson, Mark R.
Publicado 2021

NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas

por Osborne, Jihan K., Guerra, Marcy L., Gonzales, Joshua X., McMillan, Elizabeth A., Minna, John D., Cobb, Melanie H.
Publicado 2014

Chromomycin A(2) potently inhibits glucose-stimulated insulin secretion from pancreatic β cells

por Kalwat, Michael A., Hwang, In Hyun, Macho, Jocelyn, Grzemska, Magdalena G., Yang, Jonathan Z., McGlynn, Kathleen, MacMillan, John B., Cobb, Melanie H.
Publicado 2018

The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors

por He, Min, Liu, Shanshan, Gallolu Kankanamalage, Sachith, Borromeo, Mark D., Girard, Luc, Gazdar, Adi F., Minna, John D., Johnson, Jane E., Cobb, Melanie H.
Publicado 2018

WNK1 collaborates with TGF-β in endothelial cell junction turnover and angiogenesis

por Jaykumar, Ankita B., Plumber, Sakina, Barry, David M., Binns, Derk, Wichaidit, Chonlarat, Grzemska, Magdalena, Earnest, Svetlana, Goldsmith, Elizabeth J., Cleaver, Ondine, Cobb, Melanie H.
Publicado 2022

Small molecule glucagon release inhibitors with activity in human islets

por Kalwat, Michael A., Rodrigues-dos-Santos, Karina, Binns, Derk D., Wei, Shuguang, Zhou, Anwu, Evans, Matthew R., Posner, Bruce A., Roth, Michael G., Cobb, Melanie H.
Publicado 2023

Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells

por Wang, Xu-Dong, Hu, Rongkuan, Ding, Qing, Savage, Trisha K., Huffman, Kenneth E., Williams, Noelle, Cobb, Melanie H., Minna, John D., Johnson, Jane E., Yu, Yonghao
Publicado 2019

Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells

por Zaganjor, Elma, Osborne, Jihan K., Weil, Lauren M., Diaz-Martinez, Laura A., Gonzales, Joshua X., Singel, Stina M., Larsen, Jill E., Girard, Luc, Minna, John D., Cobb, Melanie H.
Publicado 2013

Control of Podocyte and Glomerular Capillary Wall Structure and Elasticity by WNK1 Kinase

por Liu, Zhenan, Yoon, Joonho, Wichaidit, Chonlarat, Jaykumar, Ankita B., Dbouk, Hashem A., Embry, Addie E., Liu, Liping, Henderson, Joel M., Chang, Audrey N., Cobb, Melanie H., Miller, Richard Tyler
Publicado 2021

Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons

por Bishop, Hannah I., Cobb, Melanie M., Kirmiz, Michael, Parajuli, Laxmi K., Mandikian, Danielle, Philp, Ashleigh M., Melnik, Mikhail, Kuja-Panula, Juha, Rauvala, Heikki, Shigemoto, Ryuichi, Murray, Karl D., Trimmer, James S.
Publicado 2018

A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization

por Thiffault, Isabelle, Speca, David J., Austin, Daniel C., Cobb, Melanie M., Eum, Kenneth S., Safina, Nicole P., Grote, Lauren, Farrow, Emily G., Miller, Neil, Soden, Sarah, Kingsmore, Stephen F., Trimmer, James S., Saunders, Carol J., Sack, Jon T.
Publicado 2015

Hydrostatic Pressure Sensing by WNK kinases

por Humphreys, John M., Teixeira, Liliana R., Akella, Radha, He, Haixia, Kannangara, Ashari R., Sekulski, Kamil, Pleinis, John, Liwocha, Joanna, Jiou, Jenny, Servage, Kelly A., Orth, Kim, Joachimiak, Lukasz, Rizo, Josep, Cobb, Melanie H., Brautigam, Chad A., Rodan, Aylin R., Goldsmith, Elizabeth J.
Publicado 2023