Characterization of chronic and acute ESA hyporesponse: a retrospective cohort study of hemodialysis patients

por Sibbel, Scott P., Koro, Carol E., Brunelli, Steven M., Cobitz, Alexander R.
Publicado 2015

An Exploratory Study of Daprodustat in Erythropoietin-Hyporesponsive Subjects

por Cizman, Borut, Sykes, Andy P., Paul, Gitanjali, Zeig, Steven, Cobitz, Alexander R.
Publicado 2018

Safety of daprodustat in patients with anemia of chronic kidney disease: A pooled analysis of phase 3 studies in Japan

por Nangaku, Masaomi, Akizawa, Tadao, Nagakubo, Takashi, Yonekawa, Taeko, Kimura, Toshifumi, Endo, Yukihiro, Cobitz, Alexander
Publicado 2022

The drug interaction potential of daprodustat when coadministered with pioglitazone, rosuvastatin, or trimethoprim in healthy subjects

por Caltabiano, Stephen, Mahar, Kelly M., Lister, Karyn, Tenero, David, Ravindranath, Ramiya, Cizman, Borut, Cobitz, Alexander R.
Publicado 2018

A randomized, 29-day, dose-ranging, efficacy and safety study of daprodustat, administered three times weekly in patients with anemia on hemodialysis

por Bailey, Christine K., Caltabiano, Stephen, Cobitz, Alexander R., Huang, Chun, Mahar, Kelly M., Patel, Vickas V.
Publicado 2019

Efficacy and safety of daprodustat in Japanese peritoneal dialysis patients

por Kanai, Hidetoshi, Nangaku, Masaomi, Nagai, Reiko, Okuda, Nobuhiko, Kurata, Kyo, Nagakubo, Takashi, Endo, Yukihiro, Cobitz, Alexander
Publicado 2021

Anemia and mortality in patients with nondialysis-dependent chronic kidney disease

por Stirnadel-Farrant, Heide A., Luo, Jiacong, Kler, Lata, Cizman, Borut, Jones, Delyth, Brunelli, Steven M., Cobitz, Alexander R.
Publicado 2018

Pharmacokinetics of Daprodustat and Metabolites in Individuals with Normal and Impaired Hepatic Function

por Mahar, Kelly M., Shaddinger, Bonnie C., Ramanjineyulu, Bandi, Andrews, Susan, Caltabiano, Stephen, Lindsay, Alistair C., Cobitz, Alexander R.
Publicado 2022

Effect of renal function and dialysis modality on daprodustat and predominant metabolite exposure

por Caltabiano, Stephen, Cizman, Borut, Burns, Olivia, Mahar, Kelly M, Johnson, Brendan M, Ramanjineyulu, Bandi, Serbest, Gulyeter, Cobitz, Alexander R
Publicado 2019

Cardiovascular Event Rates Among Hemodialysis Patients Across Geographical Regions—A Snapshot From The Dialysis Outcomes and Practice Patterns Study (DOPPS)

por Stirnadel-Farrant, Heide A., Karaboyas, Angelo, Cizman, Borut, Bieber, Brian A., Kler, Lata, Jones, Delyth, Cobitz, Alexander R., Robinson, Bruce M.
Publicado 2019

Daprodustat for anemia: a 24-week, open-label, randomized controlled trial in participants on hemodialysis

por Meadowcroft, Amy M, Cizman, Borut, Holdstock, Louis, Biswas, Nandita, Johnson, Brendan M, Jones, Delyth, Nossuli, A Kaldun, Lepore, John J, Aarup, Michael, Cobitz, Alexander R
Publicado 2018

Daprodustat for anemia: a 24-week, open-label, randomized controlled trial in participants with chronic kidney disease

por Holdstock, Louis, Cizman, Borut, Meadowcroft, Amy M, Biswas, Nandita, Johnson, Brendan M, Jones, Delyth, Kim, Sung Gyun, Zeig, Steven, Lepore, John J, Cobitz, Alexander R
Publicado 2018

Clinical Pharmacokinetics of Daprodustat: Results of an Absorption, Distribution, and Excretion Study With Intravenous Microtracer and Concomitant Oral Doses for Bioavailability De...

por Mahar, Kelly M., Caltabiano, Stephen, Andrews, Susan, Ramanjineyulu, Bandi, Chen, Liangfu, Young, Graeme, Pereira, Adrian, Lindsay, Alistair C., van den Berg, Frans, Cobitz, Alexander R.
Publicado 2021

Mechanism of action study to evaluate the effect of rosiglitazone on bone in postmenopausal women with type 2 diabetes mellitus: rationale, study design and baseline characteristic...

por Fitzpatrick, Lorraine A., Bilezikian, John P., Wooddell, Margaret, Paul, Gitanjali, Kolatkar, Nikheel S., Nino, Antonio J., Miller, Colin G., Bogado, Cesar E., Arnaud, Claude D., Cobitz, Alexander R.
Publicado 2011

Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D)

por Macdougall, Iain C., Meadowcroft, Amy M., Blackorby, Allison, Cizman, Borut, Cobitz, Alexander R., Godoy, Sergio, Jha, Vivekanand, Johansen, Kirsten L., McMahon, Gearoid, Obrador, Gregorio T., Wong, Muh Geot, Singh, Ajay K.
Publicado 2023

Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial

por Singh, Ajay K, Blackorby, Allison, Cizman, Borut, Carroll, Kevin, Cobitz, Alexander R, Davies, Rich, Jha, Vivekanand, Johansen, Kirsten L, Lopes, Renato D, Kler, Lata, Macdougall, Iain C, McMurray, John J V, Meadowcroft, Amy M, Obrador, Gregorio T, Perkovic, Vlado, Solomon, Scott, Wanner, Christoph, Waikar, Sushrut S, Wheeler, David C, Wiecek, Andrzej
Publicado 2021

Efficacy and Safety of Daprodustat for Treatment of Anemia of Chronic Kidney Disease in Incident Dialysis Patients: A Randomized Clinical Trial

por Singh, Ajay K., Cizman, Borut, Carroll, Kevin, McMurray, John J. V., Perkovic, Vlado, Jha, Vivekanand, Johansen, Kirsten L., Lopes, Renato D., Macdougall, Iain C., Obrador, Gregorio T., Waikar, Sushrut S., Wanner, Christoph, Wheeler, David C., Wiecek, Andrzej, Stankus, Nicole, Strutz, Frank, Blackorby, Allison, Cobitz, Alexander R., Meadowcroft, Amy M., Paul, Gitanjali, Ranganathan, Prerna, Sedani, Sangeeta, Solomon, Scott
Publicado 2022

The ASCEND-ND trial: study design and participant characteristics

por Perkovic, Vlado, Blackorby, Allison, Cizman, Borut, Carroll, Kevin, Cobitz, Alexander R, Davies, Rich, DiMino, Tara L, Jha, Vivekanand, Johansen, Kirsten L, Lopes, Renato D, Kler, Lata, Macdougall, Iain C, McMurray, John J V, Meadowcroft, Amy M, Obrador, Gregorio T, Solomon, Scott, Taft, Lin, Wanner, Christoph, Waikar, Sushrut S, Wheeler, David C, Wiecek, Andrzej, Singh, Ajay K
Publicado 2021