Redox signalling and ageing: insights from Drosophila

por Lennicke, Claudia, Cochemé, Helena M.
Publicado 2020

Redox regulation of the insulin signalling pathway

por Lennicke, Claudia, Cochemé, Helena M.
Publicado 2021

Sugar-induced dysregulation of purine metabolism impacts lifespan

por Lennicke, Claudia, dos Santos, Eliano, Cochemé, Helena M.
Publicado 2020

Click-PEGylation – A mobility shift approach to assess the redox state of cysteines in candidate proteins

por van Leeuwen, Lucie A.G., Hinchy, Elizabeth C., Murphy, Michael P., Robb, Ellen L., Cochemé, Helena M.
Publicado 2017

Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants

por Jameson, Victoria J.A., Cochemé, Helena M., Logan, Angela, Hanton, Lyall R., Smith, Robin A.J., Murphy, Michael P.
Publicado 2015

Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster

por Menger, Katja E., James, Andrew M., Cochemé, Helena M., Harbour, Michael E., Chouchani, Edward T., Ding, Shujing, Fearnley, Ian M., Partridge, Linda, Murphy, Michael P.
Publicado 2015

Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster

por Menger, Katja E., James, Andrew M., Cochemé, Helena M., Harbour, Michael E., Chouchani, Edward T., Ding, Shujing, Fearnley, Ian M., Partridge, Linda, Murphy, Michael P.
Publicado 2015

Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

por Alic, Nazif, Andrews, T Daniel, Giannakou, Maria E, Papatheodorou, Irene, Slack, Cathy, Hoddinott, Matthew P, Cochemé, Helena M, Schuster, Eugene F, Thornton, Janet M, Partridge, Linda
Publicado 2011

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

por Cabreiro, Filipe, Au, Catherine, Leung, Kit-Yi, Vergara-Irigaray, Nuria, Cochemé, Helena M., Noori, Tahereh, Weinkove, David, Schuster, Eugene, Greene, Nicholas D.E., Gems, David
Publicado 2013

Myostatin-like proteins regulate synaptic function and neuronal morphology

por Augustin, Hrvoje, McGourty, Kieran, Steinert, Joern R., Cochemé, Helena M., Adcott, Jennifer, Cabecinha, Melissa, Vincent, Alec, Halff, Els F., Kittler, Josef T., Boucrot, Emmanuel, Partridge, Linda
Publicado 2017

Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction

por Kinghorn, Kerri J., Castillo-Quan, Jorge Iván, Bartolome, Fernando, Angelova, Plamena R., Li, Li, Pope, Simon, Cochemé, Helena M., Khan, Shabana, Asghari, Shabnam, Bhatia, Kailash P., Hardy, John, Abramov, Andrey Y., Partridge, Linda
Publicado 2015

Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila

por Bjedov, Ivana, Cochemé, Helena M., Foley, Andrea, Wieser, Daniela, Woodling, Nathaniel S., Castillo-Quan, Jorge Iván, Norvaisas, Povilas, Lujan, Celia, Regan, Jennifer C., Toivonen, Janne M., Murphy, Michael P., Thornton, Janet, Kinghorn, Kerri J., Neufeld, Thomas P., Cabreiro, Filipe, Partridge, Linda
Publicado 2020

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

por Kerr, Fiona, Sofola-Adesakin, Oyinkan, Ivanov, Dobril K., Gatliff, Jemma, Gomez Perez-Nievas, Beatriz, Bertrand, Hélène C., Martinez, Pedro, Callard, Rebecca, Snoeren, Inge, Cochemé, Helena M., Adcott, Jennifer, Khericha, Mobina, Castillo-Quan, Jorge Iván, Wells, Geoffrey, Noble, Wendy, Thornton, Janet, Partridge, Linda
Publicado 2017

Sugar-Induced Obesity and Insulin Resistance Are Uncoupled from Shortened Survival in Drosophila

por van Dam, Esther, van Leeuwen, Lucie A.G., dos Santos, Eliano, James, Joel, Best, Lena, Lennicke, Claudia, Vincent, Alec J., Marinos, Georgios, Foley, Andrea, Buricova, Marcela, Mokochinski, Joao B., Kramer, Holger B., Lieb, Wolfgang, Laudes, Matthias, Franke, Andre, Kaleta, Christoph, Cochemé, Helena M.
Publicado 2020

Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry

por Logan, Angela, Pell, Victoria R., Shaffer, Karl J., Evans, Cameron, Stanley, Nathan J., Robb, Ellen L., Prime, Tracy A., Chouchani, Edward T., Cochemé, Helena M., Fearnley, Ian M., Vidoni, Sara, James, Andrew M., Porteous, Carolyn M., Partridge, Linda, Krieg, Thomas, Smith, Robin A.J., Murphy, Michael P.
Publicado 2016

Measurement of H(2)O(2) within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix

por Cochemé, Helena M., Quin, Caroline, McQuaker, Stephen J., Cabreiro, Filipe, Logan, Angela, Prime, Tracy A., Abakumova, Irina, Patel, Jigna V., Fearnley, Ian M., James, Andrew M., Porteous, Carolyn M., Smith, Robin A.J., Saeed, Saima, Carré, Jane E., Singer, Mervyn, Gems, David, Hartley, Richard C., Partridge, Linda, Murphy, Michael P.
Publicado 2011

Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy

por Pryor, Rosina, Norvaisas, Povilas, Marinos, Georgios, Best, Lena, Thingholm, Louise B., Quintaneiro, Leonor M., De Haes, Wouter, Esser, Daniela, Waschina, Silvio, Lujan, Celia, Smith, Reuben L., Scott, Timothy A., Martinez-Martinez, Daniel, Woodward, Orla, Bryson, Kevin, Laudes, Matthias, Lieb, Wolfgang, Houtkooper, Riekelt H., Franke, Andre, Temmerman, Liesbet, Bjedov, Ivana, Cochemé, Helena M., Kaleta, Christoph, Cabreiro, Filipe
Publicado 2019

Oxidative stress and life histories: unresolved issues and current needs

por Speakman, John R., Blount, Jonathan D., Bronikowski, Anne M., Buffenstein, Rochelle, Isaksson, Caroline, Kirkwood, Tom B. L., Monaghan, Pat, Ozanne, Susan E., Beaulieu, Michaël, Briga, Michael, Carr, Sarah K., Christensen, Louise L., Cochemé, Helena M., Cram, Dominic L., Dantzer, Ben, Harper, Jim M., Jurk, Diana, King, Annette, Noguera, Jose C., Salin, Karine, Sild, Elin, Simons, Mirre J. P., Smith, Shona, Stier, Antoine, Tobler, Michael, Vitikainen, Emma, Peaker, Malcolm, Selman, Colin
Publicado 2015