Innate immunity to malaria: The good, the bad and the unknown

por Pohl, Kai, Cockburn, Ian A.
Publicado 2022

The development and function of CD11c(+) atypical B cells - insights from single cell analysis

por Gao, Xin, Cockburn, Ian A.
Publicado 2022

The three Rs: Recruitment, Retention and Residence of leukocytes in the liver

por McNamara, Hayley A, Cockburn, Ian A
Publicado 2016

Antibody and B cell responses to Plasmodium sporozoites

por Dups, Johanna N., Pepper, Marion, Cockburn, Ian A.
Publicado 2014

B7-H1 Blockade Increases Survival of Dysfunctional CD8(+) T Cells and Confers Protection against Leishmania donovani Infections

por Joshi, Trupti, Rodriguez, Susana, Perovic, Vladimir, Cockburn, Ian A., Stäger, Simona
Publicado 2009

Clustering of Activated CD8 T Cells Around Malaria-Infected Hepatocytes Is Rapid and Is Driven by Antigen-Specific Cells

por Kelemen, Reka K., Rajakaruna, Harshana, Cockburn, Ian A., Ganusov, Vitaly V.
Publicado 2019

A New Method Based on the von Mises-Fisher Distribution Shows that a Minority of Liver-Localized CD8 T Cells Display Hard-To-Detect Attraction to Plasmodium-Infected Hepatocytes

por Zenkov, Viktor S., O’Connor, James H., Cockburn, Ian A., Ganusov, Vitaly V.
Publicado 2022

Unique transcriptional profile of liver-resident memory CD8(+) T cells induced by immunization with malaria sporozoites

por Tse, Sze-Wah, Cockburn, Ian A., Zhang, Hao, Scott, Alan L., Zavala, Fidel
Publicado 2013

IL-4 receptor expression on CD8(+) T cells is required for the development of protective memory responses against liver stages of malaria parasites

por Morrot, Alexandre, Hafalla, Julius C.R., Cockburn, Ian A., Carvalho, Luzia H., Zavala, Fidel
Publicado 2005

CD4(+) T Cells Modulate Expansion and Survival but Not Functional Properties of Effector and Memory CD8(+) T Cells Induced by Malaria Sporozoites

por Overstreet, Michael G., Chen, Yun-Chi, Cockburn, Ian A., Tse, Sze-Wah, Zavala, Fidel
Publicado 2011

Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

por Cockburn, Ian A., Tse, Sze-Wah, Radtke, Andrea J., Srinivasan, Prakash, Chen, Yun-Chi, Sinnis, Photini, Zavala, Fidel
Publicado 2011

Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites

por Cockburn, Ian A., Chen, Yun-Chi, Overstreet, Michael G., Lees, Jason R., van Rooijen, Nico, Farber, Donna L., Zavala, Fidel
Publicado 2010

Splenic Dendritic Cells and Macrophages Drive B Cells to Adopt a Plasmablast Cell Fate

por McNamara, Hayley A., Lahoud, Mireille H., Cai, Yeping, Durrant-Whyte, Jessica, O’Connor, James H., Caminschi, Irina, Cockburn, Ian A.
Publicado 2022

Lymph-Node Resident CD8α(+) Dendritic Cells Capture Antigens from Migratory Malaria Sporozoites and Induce CD8(+) T Cell Responses

por Radtke, Andrea J., Kastenmüller, Wolfgang, Espinosa, Diego A., Gerner, Michael Y., Tse, Sze-Wah, Sinnis, Photini, Germain, Ronald N., Zavala, Fidel P., Cockburn, Ian A.
Publicado 2015

Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes

por Chatterjee, Deepyan, Lewis, Fiona J., Sutton, Henry J., Kaczmarski, Joe A., Gao, Xin, Cai, Yeping, McNamara, Hayley A., Jackson, Colin J., Cockburn, Ian A.
Publicado 2021

Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype

por Aye, Racheal, Sutton, Henry J., Nduati, Eunice W., Kai, Oscar, Mwacharo, Jedida, Musyoki, Jennifer, Otieno, Edward, Wambua, Juliana, Bejon, Philip, Cockburn, Ian A., Ndungu, Francis M.
Publicado 2020

Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites

por Rajendran, Esther, Hapuarachchi, Sanduni V., Miller, Catherine M., Fairweather, Stephen J., Cai, Yeping, Smith, Nicholas C., Cockburn, Ian A., Bröer, Stefan, Kirk, Kiaran, van Dooren, Giel G.
Publicado 2017

T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein

por Fisher, Camilla R., Sutton, Henry J., Kaczmarski, Joe A., McNamara, Hayley A., Clifton, Ben, Mitchell, Joshua, Cai, Yeping, Dups, Johanna N., D'Arcy, Nicholas J., Singh, Mandeep, Chuah, Aaron, Peat, Thomas S., Jackson, Colin J., Cockburn, Ian A.
Publicado 2017

T(FH)-derived dopamine accelerates productive synapses in germinal centres

por Papa, Ilenia, Saliba, David, Ponzoni, Maurilio, Bustamante, Sonia, Canete, Pablo F., Gonzalez-Figueroa, Paula, McNamara, Hayley A., Valvo, Salvatore, Grimbaldeston, Michele, Sweet, Rebecca A., Vohra, Harpreet, Cockburn, Ian A., Meyer-Hermann, Michael, Dustin, Michael L., Doglioni, Claudio, Vinuesa, Carola G.
Publicado 2017

Extrafollicular Plasmablasts Present in the Acute Phase of Infections Express High Levels of PD-L1 and Are Able to Limit T Cell Response

por Serrán, Melisa Gorosito, Vernengo, Facundo Fiocca, Almada, Laura, Beccaria, Cristian G., Gazzoni, Yamila, Canete, Pablo F., Roco, Jonathan A., Boari, Jimena Tosello, Ramello, Maria Cecilia, Wehrens, Ellen, Cai, Yeping, Zuniga, Elina I., Montes, Carolina L., Cockburn, Ian A., Rodriguez, Eva V. Acosta, Vinuesa, Carola G., Gruppi, Adriana
Publicado 2022