An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations

por Mullen, Joseph, Cockell, Simon J., Woollard, Peter, Wipat, Anil
Publicado 2016

Misincorporation by RNA polymerase is a major source of transcription pausing in vivo

por James, Katherine, Gamba, Pamela, Cockell, Simon J., Zenkin, Nikolay
Publicado 2017

Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae

por Dubarry, Marion, Lawless, Conor, Banks, A. Peter, Cockell, Simon, Lydall, David
Publicado 2015

Understanding the complexity of retina and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future prospe...

por Zerti, Darin, Collin, Joseph, Queen, Rachel, Cockell, Simon J., Lako, Majlinda
Publicado 2019

Integration of probabilistic functional networks without an external Gold Standard

por James, Katherine, Alsobhe, Aoesha, Cockell, Simon J, Wipat, Anil, Pocock, Matthew
Publicado 2022

Contribution of natural antisense transcription to an endogenous siRNA signature in human cells

por Werner, Andreas, Cockell, Simon, Falconer, Jane, Carlile, Mark, Alnumeir, Sammer, Robinson, John
Publicado 2014

Mining integrated semantic networks for drug repositioning opportunities

por Mullen, Joseph, Cockell, Simon J., Tipney, Hannah, Woollard, Peter M., Wipat, Anil
Publicado 2016

Correlation of Infinium HumanMethylation450K and MethylationEPIC BeadChip arrays in cartilage

por Cheung, Kathleen, Burgers, Marjolein J., Young, David A., Cockell, Simon, Reynard, Louise N.
Publicado 2019

Influence of Genetic Variations in Selenoprotein Genes on the Pattern of Gene Expression after Supplementation with Brazil Nuts

por Donadio, Janaina L. S., Rogero, Marcelo M., Cockell, Simon, Hesketh, John, Cozzolino, Silvia M. F.
Publicado 2017

The Zinc Finger Protein ZNF658 Regulates the Transcription of Genes Involved in Zinc Homeostasis and Affects Ribosome Biogenesis through the Zinc Transcriptional Regulatory Element

por Ogo, Ogo A., Tyson, John, Cockell, Simon J., Howard, Alison, Valentine, Ruth A., Ford, Dianne
Publicado 2015

Bayesian integration of networks without gold standards

por Weile, Jochen, James, Katherine, Hallinan, Jennifer, Cockell, Simon J., Lord, Phillip, Wipat, Anil, Wilkinson, Darren J.
Publicado 2012

Deconstructing Retinal Organoids: Single Cell RNA‐Seq Reveals the Cellular Components of Human Pluripotent Stem Cell‐Derived Retina

por Collin, Joseph, Queen, Rachel, Zerti, Darin, Dorgau, Birthe, Hussain, Rafiqul, Coxhead, Jonathan, Cockell, Simon, Lako, Majlinda
Publicado 2019

Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females

por Pease, Louise I., Clegg, Peter D., Proctor, Carole J., Shanley, Daryl J., Cockell, Simon J., Peffers, Mandy J.
Publicado 2017

Therapeutic wavelengths of ultraviolet B radiation activate apoptotic, circadian rhythm, redox signalling and key canonical pathways in psoriatic epidermis

por Addison, Rachel, Weatherhead, Sophie C., Pawitri, Anandika, Smith, Graham R., Rider, Ashley, Grantham, Henry J., Cockell, Simon J., Reynolds, Nick J.
Publicado 2021

Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome

por Davies, Helen R., Hodgson, Kirsty, Schwalbe, Edward, Coxhead, Jonathan, Sinclair, Naomi, Zou, Xueqing, Cockell, Simon, Husain, Akhtar, Nik-Zainal, Serena, Rajan, Neil
Publicado 2019

Customizable views on semantically integrated networks for systems biology

por Weile, Jochen, Pocock, Matthew, Cockell, Simon J., Lord, Phillip, Dewar, James M., Holstein, Eva−Maria, Wilkinson, Darren, Lydall, David, Hallinan, Jennifer, Wipat, Anil
Publicado 2011

RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation

por Szołtysek, Katarzyna, Janus, Patryk, Zając, Gracjana, Stokowy, Tomasz, Walaszczyk, Anna, Widłak, Wiesława, Wojtaś, Bartosz, Gielniewski, Bartłomiej, Cockell, Simon, Perkins, Neil D., Kimmel, Marek, Widlak, Piotr
Publicado 2018

Utility of B-13 Progenitor-Derived Hepatocytes in Hepatotoxicity and Genotoxicity Studies

por Probert, Philip M. E., Chung, Git W., Cockell, Simon J., Agius, Loranne, Mosesso, Pasquale, White, Steven A., Oakley, Fiona, Brown, Colin D. A., Wright, Matthew C.
Publicado 2014

B-cell activity markers are associated with different disease activity domains in primary Sjögren’s syndrome

por James, Katherine, Chipeta, Chimwemwe, Parker, Antony, Harding, Stephen, Cockell, Simon J, Gillespie, Colin S, Hallinan, Jennifer, Barone, Francesca, Bowman, Simon J, Ng, Wan-Fai, Fisher, Benjamin A
Publicado 2018

A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures

por Govaere, Olivier, Hasoon, Megan, Alexander, Leigh, Cockell, Simon, Tiniakos, Dina, Ekstedt, Mattias, Schattenberg, Jörn M., Boursier, Jerome, Bugianesi, Elisabetta, Ratziu, Vlad, Daly, Ann K., Anstee, Quentin M.
Publicado 2023