Genetically Engineering a Susceptible Mouse Model for MERS-CoV-Induced Acute Respiratory Distress Syndrome

por Leist, Sarah R., Cockrell, Adam S.
Publicado 2019

Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses

por Cockrell, Adam S., Beall, Anne, Yount, Boyd, Baric, Ralph
Publicado 2017

Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice

por Cockrell, Adam S., Leist, Sarah R., Douglas, Madeline G., Baric, Ralph S.
Publicado 2018

The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles

por Cockrell, Adam S, van Praag, Henriette, Santistevan, Nicholas, Ma, Hong, Kafri, Tal
Publicado 2011

Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease

por Douglas, Madeline G., Kocher, Jacob F., Scobey, Trevor, Baric, Ralph S., Cockrell, Adam S.
Publicado 2018

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

por Cockrell, Adam S., Yount, Boyd L., Scobey, Trevor, Jensen, Kara, Douglas, Madeline, Beall, Anne, Tang, Xian-Chun, Marasco, Wayne A., Heise, Mark T., Baric, Ralph S.
Publicado 2016

A randomized, controlled, feasibility study of RD‐X19 in subjects with mild‐to‐moderate COVID‐19 in the outpatient setting

por Stasko, Nathan, Cockrell, Adam S., Kocher, Jacob F., Henson, Ibrahim, Emerson, David, Wang, Ye, Smith, Jonathan R., Henderson, Nathan H., Wood, Hillary, Bradrick, Shelton S., Jones, Terry, Santander, Jorge, McNeil, John G.
Publicado 2022

A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques

por Cockrell, Adam S., Johnson, Joshua C., Moore, Ian N., Liu, David X., Bock, Kevin W., Douglas, Madeline G., Graham, Rachel L., Solomon, Jeffrey, Torzewski, Lisa, Bartos, Christopher, Hart, Randy, Baric, Ralph S., Johnson, Reed F.
Publicado 2018

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

por Menachery, Vineet D., Gralinski, Lisa E., Mitchell, Hugh D., Dinnon, Kenneth H., Leist, Sarah R., Yount, Boyd L., Graham, Rachel L., McAnarney, Eileen T., Stratton, Kelly G., Cockrell, Adam S., Debbink, Kari, Sims, Amy C., Waters, Katrina M., Baric, Ralph S.
Publicado 2017

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

por Menachery, Vineet D., Mitchell, Hugh D., Cockrell, Adam S., Gralinski, Lisa E., Yount, Boyd L., Graham, Rachel L., McAnarney, Eileen T., Douglas, Madeline G., Scobey, Trevor, Beall, Anne, Dinnon, Kenneth, Kocher, Jacob F., Hale, Andrew E., Stratton, Kelly G., Waters, Katrina M., Baric, Ralph S.
Publicado 2017

Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice

por Maurizio, Paul L., Ferris, Martin T., Keele, Gregory R., Miller, Darla R., Shaw, Ginger D., Whitmore, Alan C., West, Ande, Morrison, Clayton R., Noll, Kelsey E., Plante, Kenneth S., Cockrell, Adam S., Threadgill, David W., Pardo-Manuel de Villena, Fernando, Baric, Ralph S., Heise, Mark T., Valdar, William
Publicado 2017

Visible blue light inhibits infection and replication of SARS-CoV-2 at doses that are well-tolerated by human respiratory tissue

por Stasko, Nathan, Kocher, Jacob F., Annas, Abigail, Henson, Ibrahim, Seitz, Theresa S., Miller, Joy M., Arwood, Leslee, Roberts, Rachel C., Womble, Thomas M., Keller, Emily G., Emerson, Soren, Bergmann, Michael, Sheesley, Ashley N. Y., Strong, Rebecca J., Hurst, Brett L., Emerson, David, Tarbet, E. Bart, Bradrick, Shelton S., Cockrell, Adam S.
Publicado 2021

Broad-spectrum Investigational Agent GS-5734 for the Treatment of Ebola, MERS Coronavirus and Other Pathogenic Viral Infections with High Outbreak Potential

por Jordan, Robert, Hogg, Alison, Warren, Travis, De Wit, Emmie, Sheahan, Timothy, Lo, Michael, Soloveva, Veronica, Weidner, Jessica, Gomba, Laura, Feldmann, Friederike, Cronin, Jacqueline, Sims, Amy, Cockrell, Adam, Feng, Joy, Trantcheva, Iva, Babusis, Darius, Porter-Poulin, Danielle, Bannister, Roy, Mackman, Richard, Siegel, Dustin, Ray, Adrian, Denison, Mark, Spiropoulou, Christina, Nichol, Stuart, Cihlar, Tomas, Baric, Ralph, Feldmann, Heinrich, Bavari, Sina
Publicado 2017

The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis

por Chefer, Svetlana, Seidel, Jurgen, Cockrell, Adam S., Yount, Boyd, Solomon, Jeffrey, Hagen, Katie R., Liu, David X., Huzella, Louis M., Kumar, Mia R., Postnikova, Elena, Bohannon, J. Kyle, Lackemeyer, Matthew G., Cooper, Kurt, Endlich-Frazier, Ariel, Sharma, Heema, Thomasson, David, Bartos, Christopher, Sayre, Philip J., Sims, Amy, Dyall, Julie, Holbrook, Michael R., Jahrling, Peter B., Baric, Ralph S., Johnson, Reed F.
Publicado 2018

Precision mouse models with expanded tropism for human pathogens

por Wahl, Angela, De, Chandrav, Abad Fernandez, Maria, Lenarcic, Erik M., Xu, Yinyan, Cockrell, Adam S., Cleary, Rachel A., Johnson, Claire E., Schramm, Nathaniel J., Rank, Laura M., Newsome, Isabel G., Vincent, Heather A., Sanders, Wes, Aguilera-Sandoval, Christian R., Boone, Allison, Hildebrand, William H., Dayton, Paul A., Baric, Ralph S., Pickles, Raymond J., Braunstein, Miriam, Moorman, Nathaniel J., Goonetilleke, Nilu, Victor Garcia, J.
Publicado 2019

Hypergraph models of biological networks to identify genes critical to pathogenic viral response

por Feng, Song, Heath, Emily, Jefferson, Brett, Joslyn, Cliff, Kvinge, Henry, Mitchell, Hugh D., Praggastis, Brenda, Eisfeld, Amie J., Sims, Amy C., Thackray, Larissa B., Fan, Shufang, Walters, Kevin B., Halfmann, Peter J., Westhoff-Smith, Danielle, Tan, Qing, Menachery, Vineet D., Sheahan, Timothy P., Cockrell, Adam S., Kocher, Jacob F., Stratton, Kelly G., Heller, Natalie C., Bramer, Lisa M., Diamond, Michael S., Baric, Ralph S., Waters, Katrina M., Kawaoka, Yoshihiro, McDermott, Jason E., Purvine, Emilie
Publicado 2021