Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvi...

por Guo, Ailin, Lu, Pin, Coffey, Greg, Conley, Pamela, Pandey, Anjali, Wang, Y. Lynn
Publicado 2017

Methotrexate and a spleen tyrosine kinase inhibitor cooperate to inhibit responses to peripheral blood B cells in rheumatoid arthritis

por Coffey, Greg, Betz, Andreas, Graf, Jonathan, Stephens, Gillian, Hua Lin, Pei, Imboden, John, Sinha, Uma
Publicado 2013

Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti-tumor activity in both ABC and GCB types of diffuse large B cell lymphoma

por Ma, Jiao, Xing, Wei, Coffey, Greg, Dresser, Karen, Lu, Kellie, Guo, Ailin, Raca, Gordana, Pandey, Anjali, Conley, Pamela, Yu, Hongbo, Wang, Y. Lynn
Publicado 2015

PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers

por Coffey, Greg, Rani, Aradhana, Betz, Andreas, Pak, Yvonne, Haberstock‐Debic, Helena, Pandey, Anjali, Hollenbach, Stanley, Gretler, Daniel D., Mant, Tim, Jurcevic, Stipo, Sinha, Uma
Publicado 2016