The oncolytic effects of reovirus in canine solid tumor cell lines

por IGASE, Masaya, HWANG, Chung Chew, COFFEY, Matt, OKUDA, Masaru, NOGUCHI, Shunsuke, MIZUNO, Takuya
Publicado 2015

The combination of intravenous Reolysin and gemcitabine induces reovirus replication and endoplasmic reticular stress in a patient with KRAS-activated pancreatic cancer

por Mahalingam, Devalingam, Patel, Sukeshi, Nuovo, Gerard, Gill, George, Selvaggi, Giovanni, Coffey, Matt, Nawrocki, Steffan T.
Publicado 2015

Reovirus activated NK cells show enhanced cetuximab mediated antibody-dependent cellular cytotoxicity against colorectal cancer cells

por Zhao, Xing, Rajasekaran, Narendiran, Chester, Cariad, Yonezawa, Atsushi, Dutt, Suparna, Coffey, Matt, Kohrt, Holbrook E
Publicado 2015

Immune characterization of metastatic colorectal cancer patients post reovirus administration

por Parakrama, Ruwan, Fogel, Elisha, Chandy, Carol, Augustine, Titto, Coffey, Matt, Tesfa, Lydia, Goel, Sanjay, Maitra, Radhashree
Publicado 2020

Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

por Ungerechts, Guy, Bossow, Sascha, Leuchs, Barbara, Holm, Per S, Rommelaere, Jean, Coffey, Matt, Coffin, Rob, Bell, John, Nettelbeck, Dirk M
Publicado 2016

Combination Therapy with Reovirus and ATM Inhibitor Enhances Cell Death and Virus Replication in Canine Melanoma

por Igase, Masaya, Shibutani, Shusaku, Kurogouchi, Yosuke, Fujiki, Noriyuki, Hwang, Chung Chew, Coffey, Matt, Noguchi, Shunsuke, Nemoto, Yuki, Mizuno, Takuya
Publicado 2019

Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune priming

por Steele, Lynette, Errington, Fiona, Prestwich, Robin, Ilett, Elizabeth, Harrington, Kevin, Pandha, Hardev, Coffey, Matt, Selby, Peter, Vile, Richard, Melcher, Alan
Publicado 2011

Oncolytic Reovirus-Mediated Recruitment of Early Innate Immune Responses Reverses Immunotherapy Resistance in Prostate Tumors

por Annels, Nicola E., Simpson, Guy R., Denyer, Mick, Arif, Mehreen, Coffey, Matt, Melcher, Alan, Harrington, Kevin, Vile, Richard, Pandha, Hardev
Publicado 2020

Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling

por McEntee, Gráinne, Kyula, Joan N., Mansfield, David, Smith, Henry, Wilkinson, Michelle, Gregory, Claire, Roulstone, Victoria, Coffey, Matt, Harrington, Kevin J.
Publicado 2016

Oncolytic Reovirus in Canine Mast Cell Tumor

por Hwang, Chung Chew, Umeki, Saori, Kubo, Masahito, Hayashi, Toshiharu, Shimoda, Hiroshi, Mochizuki, Masami, Maeda, Ken, Baba, Kenji, Hiraoka, Hiroko, Coffey, Matt, Okuda, Masaru, Mizuno, Takuya
Publicado 2013

Phase I trial of sargramostim/pelareorep therapy in pediatric patients with recurrent or refractory high-grade brain tumors

por Schuelke, Matthew R, Gundelach, Justin H, Coffey, Matt, West, Emma, Scott, Karen, Johnson, Derek R, Samson, Adel, Melcher, Alan, Vile, Richard G, Bram, Richard J
Publicado 2022

Reovirus-Mediated Cytotoxicity and Enhancement of Innate Immune Responses Against Acute Myeloid Leukemia

por Hall, Kathryn, Scott, Karen J., Rose, Ailsa, Desborough, Michael, Harrington, Kevin, Pandha, Hardev, Parrish, Christopher, Vile, Richard, Coffey, Matt, Bowen, David, Errington-Mais, Fiona, Melcher, Alan A.
Publicado 2012

Diverse immunotherapies can effectively treat syngeneic brainstem tumors in the absence of overt toxicity

por Schuelke, Matthew R., Wongthida, Phonphimon, Thompson, Jill, Kottke, Timothy, Driscoll, Christopher B., Huff, Amanda L., Shim, Kevin G., Coffey, Matt, Pulido, Jose, Evgin, Laura, Vile, Richard G.
Publicado 2019

Oncolytic virus treatment differentially affects the CD56(dim) and CD56(bright) NK cell subsets in vivo and regulates a spectrum of human NK cell activity

por Wantoch, Michelle, Wilson, Erica B., Droop, Alastair P., Phillips, Sarah L., Coffey, Matt, El‐Sherbiny, Yasser M., Holmes, Tim D., Melcher, Alan A., Wetherill, Laura F., Cook, Graham P.
Publicado 2022

Prime-boost using Separate Oncolytic Viruses in Combination with Checkpoint Blockade Improves Anti-tumor Therapy

por Ilett, Elizabeth, Kottke, Timothy, Thompson, Jill, Rajani, Karishma, Zaidi, Shane, Evgin, Laura, Coffey, Matt, Ralph, Christy, Diaz, Rosa, Pandha, Hardev, Harrington, Kevin, Selby, Peter, Bram, Richard, Melcher, Alan, Vile, Richard
Publicado 2016

Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway

por Twigger, Katie, Roulstone, Victoria, Kyula, Joan, Karapanagiotou, Eleni M, Syrigos, Konstantinos N, Morgan, Richard, White, Christine, Bhide, Shreerang, Nuovo, Gerard, Coffey, Matt, Thompson, Brad, Jebar, Adel, Errington, Fiona, Melcher, Alan A, Vile, Richard G, Pandha, Hardev S, Harrington, Kevin J
Publicado 2012

Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

por Müller, Louise M E, Migneco, Gemma, Scott, Gina B, Down, Jenny, King, Sancha, Askar, Basem, Jennings, Victoria, Oyajobi, Babatunde, Scott, Karen, West, Emma, Ralph, Christy, Samson, Adel, Ilett, Elizabeth J, Muthana, Munitta, Coffey, Matt, Melcher, Alan, Parrish, Christopher, Cook, Gordon, Lawson, Michelle, Errington-Mais, Fiona
Publicado 2021

Oncolytic virus-derived type I interferon restricts CAR T cell therapy

por Evgin, Laura, Huff, Amanda L., Wongthida, Phonphimon, Thompson, Jill, Kottke, Tim, Tonne, Jason, Schuelke, Matthew, Ayasoufi, Katayoun, Driscoll, Christopher B., Shim, Kevin G., Reynolds, Pierce, Monie, Dileep D., Johnson, Aaron J., Coffey, Matt, Young, Sarah L., Archer, Gary, Sampson, John, Pulido, Jose, Perez, Luis Sanchez, Vile, Richard
Publicado 2020