Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts

por Ramachandran, Shyam, Coffin, Stephanie L., Tang, Tin-Yun, Jobaliya, Chintan D., Spengler, Ryan M., Davidson, Beverly L.
Publicado 2016

VWA3A-derived ependyma promoter drives increased therapeutic protein secretion into the CSF

por Carrell, Ellie M., Chen, Yong Hong, Ranum, Paul T., Coffin, Stephanie L., Singh, Larry N., Tecedor, Luis, Keiser, Megan S., Hudry, Eloise, Hyman, Bradley T., Davidson, Beverly L.
Publicado 2023

miR760 regulates ATXN1 levels via interaction with its 5′ untranslated region

por Nitschke, Larissa, Tewari, Ambika, Coffin, Stephanie L., Xhako, Eder, Pang, Kaifang, Gennarino, Vincenzo A., Johnson, Jennifer L., Blanco, Francisco A., Liu, Zhandong, Zoghbi, Huda Y.
Publicado 2020

Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1

por Nitschke, Larissa, Coffin, Stephanie L., Xhako, Eder, El-Najjar, Dany B., Orengo, James P., Alcala, Elizabeth, Dai, Yanwan, Wan, Ying-Wooi, Liu, Zhandong, Orr, Harry T., Zoghbi, Huda Y.
Publicado 2021

Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1

por Coffin, Stephanie L., Durham, Mark A., Nitschke, Larissa, Xhako, Eder, Brown, Amanda M., Revelli, Jean-Pierre, Gonzalez, Esmeralda Villavicencio, Lin, Tao, Handler, Hillary P., Dai, Yanwan, Trostle, Alexander J., Wan, Ying-Wooi, Liu, Zhandong, Sillitoe, Roy V., Orr, Harry T., Zoghbi, Huda Y.
Publicado 2023

Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1

por Coffin, Stephanie L., Durham, Mark A., Nitschke, Larissa, Xhako, Eder, Brown, Amanda M., Revelli, Jean-Pierre, Gonzalez, Esmeralda Villavicencio, Lin, Tao, Handler, Hillary P., Dai, Yanwan, Trostle, Alexander J., Wan, Ying-Wooi, Liu, Zhandong, Sillitoe, Roy V., Orr, Harry T., Zoghbi, Huda Y.
Publicado 2023