Perspectives on the Genetic Associations of Ankylosing Spondylitis

por Wordsworth, B. Paul, Cohen, Carla J., Davidson, Connor, Vecellio, Matteo
Publicado 2021

Chromosome conformation capture approaches to investigate 3D genome architecture in Ankylosing Spondylitis

por Davidson, Connor, Wordsworth, B. Paul, Cohen, Carla J., Knight, Julian C., Vecellio, Matteo
Publicado 2023

RUNX3 and T-Bet in Immunopathogenesis of Ankylosing Spondylitis—Novel Targets for Therapy?

por Vecellio, Matteo, Cohen, Carla J., Roberts, Amity R., Wordsworth, Paul B., Kenna, Tony J.
Publicado 2019

SHIP-Deficient Dendritic Cells, Unlike Wild Type Dendritic Cells, Suppress T Cell Proliferation via a Nitric Oxide-Independent Mechanism

por Antignano, Frann, Hamilton, Melisa, Patterson, Scott, Ho, Victor, Cohen, Carla, Levings, Megan K., Krystal, Gerald
Publicado 2011

Disruption of c-MYC Binding and Chromosomal Looping Involving Genetic Variants Associated With Ankylosing Spondylitis Upstream of the RUNX3 Promoter

por Cohen, Carla J., Davidson, Connor, Selmi, Carlo, Bowness, Paul, Knight, Julian C., Wordsworth, B. Paul, Vecellio, Matteo
Publicado 2022

The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression

por Vecellio, Matteo, Roberts, Amity R, Cohen, Carla J, Cortes, Adrian, Knight, Julian C, Bowness, Paul, Wordsworth, B Paul
Publicado 2016

An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation

por Roberts, Amity R, Vecellio, Matteo, Chen, Liye, Ridley, Anna, Cortes, Adrian, Knight, Julian C, Bowness, Paul, Cohen, Carla J, Wordsworth, B Paul
Publicado 2016

Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism

por Vecellio, Matteo, Cortes, Adrian, Roberts, Amity R, Ellis, Jonathan, Cohen, Carla Jayne, Knight, Julian C, Brown, Matthew A, Bowness, Paul, Wordsworth, Bryan Paul
Publicado 2018

Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis

por Vecellio, Matteo, Chen, Liye, Cohen, Carla J., Cortes, Adrian, Li, Yan, Bonham, Sarah, Selmi, Carlo, Brown, Matthew A., Fischer, Roman, Knight, Julian C., Wordsworth, B. Paul
Publicado 2021

Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis

por Brown, Andrew C., Cohen, Carla J., Mielczarek, Olga, Migliorini, Gabriele, Costantino, Félicie, Allcock, Alice, Davidson, Connor, Elliott, Katherine S., Fang, Hai, Lledó Lara, Alicia, Martin, Alice C., Osgood, Julie A., Sanniti, Anna, Scozzafava, Giuseppe, Vecellio, Matteo, Zhang, Ping, Black, Mary Helen, Li, Shuwei, Truong, Dongnhu, Molineros, Julio, Howe, Trevor, Wordsworth, B. Paul, Bowness, Paul, Knight, Julian C.
Publicado 2023