GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis

por Regan-Komito, Daniel, Swann, James W., Demetriou, Philippos, Cohen, E. Suzanne, Horwood, Nicole J., Sansom, Stephen N., Griseri, Thibault
Publicado 2020

Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

por Scott, Ian C., Majithiya, Jayesh B., Sanden, Caroline, Thornton, Peter, Sanders, Philip N., Moore, Tom, Guscott, Molly, Corkill, Dominic J., Erjefält, Jonas S., Cohen, E. Suzanne
Publicado 2018

The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis

por Stephenson, Katherine E., Porte, Joanne, Kelly, Aoife, Wallace, William A., Huntington, Catherine E., Overed-Sayer, Catherine L., Cohen, E. Suzanne, Jenkins, R. Gisli, John, Alison E.
Publicado 2023

Dendritic Cell-Derived TSLP Negatively Regulates HIF-1α and IL-1β During Dectin-1 Signaling

por Elder, Matthew J., Webster, Steve J., Fitzmaurice, Timothy J., Shaunak, Aran S. D., Steinmetz, Martin, Chee, Ronnie, Mallat, Ziad, Cohen, E. Suzanne, Williams, David L., Gaston, J. S. Hill, Goodall, Jane C.
Publicado 2019

Host Immunity Influences the Composition of Murine Gut Microbiota

por Van averbeke, Vincent, Berkell, Matilda, Mysara, Mohamed, Rodriguez-Ruiz, Juan Pablo, Xavier, Basil Britto, De Winter, Fien H. R., Jongers, Bart ‘s, Jairam, Ravi Kumar, Hotterbeekx, An, Goossens, Herman, Cohen, E. Suzanne, Malhotra-Kumar, Surbhi, Kumar-Singh, Samir
Publicado 2022

A helminth-derived suppressor of ST2 blocks allergic responses

por Vacca, Francesco, Chauché, Caroline, Jamwal, Abhishek, Hinchy, Elizabeth C, Heieis, Graham, Webster, Holly, Ogunkanbi, Adefunke, Sekne, Zala, Gregory, William F, Wear, Martin, Perona-Wright, Georgia, Higgins, Matthew K, Nys, Josquin A, Cohen, E Suzanne, McSorley, Henry J
Publicado 2020

Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope “tags”

por Percival-Alwyn, Jennifer L, England, Elizabeth, Kemp, Benjamin, Rapley, Laura, Davis, Nicola HE, McCarthy, Grant R, Majithiya, Jayesh B, Corkill, Dominic J, Welsted, Sarah, Minton, Kevin, Cohen, E Suzanne, Robinson, Matthew J, Dobson, Claire, Wilkinson, Trevor CI, Vaughan, Tristan J, Groves, Maria AT, Tigue, Natalie J
Publicado 2014

Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages

por Lu, Yuning, Basatemur, Gemma, Scott, Ian C., Chiarugi, Davide, Clement, Marc, Harrison, James, Jugdaohsingh, Ravin, Yu, Xian, Newland, Stephen A., Jolin, Helen E., Li, Xuan, Chen, Xiao, Szymanska, Monika, Haraldsen, Guttorm, Palmer, Gaby, Fallon, Padraic G., Cohen, E. Suzanne, McKenzie, Andrew N.J., Mallat, Ziad
Publicado 2020

Neutrophil GM‐CSF receptor dynamics in acute lung injury

por De Alessandris, Silvia, Ferguson, G. John, Dodd, Alison J., Juss, Jatinder K., Devaprasad, Abhinandan, Piper, Siân, Wyatt, Owen, Killick, Helen, Corkill, Dominic J., Cohen, E. Suzanne, Pandit, Aridaman, Radstake, Timothy R.D.J., Simmonds, Rosalind, Condliffe, Alison M., Sleeman, Matthew A., Cowburn, Andrew S., Finch, Donna K., Chilvers, Edwin R.
Publicado 2019

A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue

por Rana, Batika M.J., Jou, Eric, Barlow, Jillian L., Rodriguez-Rodriguez, Noe, Walker, Jennifer A., Knox, Claire, Jolin, Helen E., Hardman, Clare S., Sivasubramaniam, Meera, Szeto, Aydan, Cohen, E. Suzanne, Scott, Ian C., Sleeman, Matthew A., Chidomere, Chiamaka I., Cruz Migoni, Sara, Caamano, Jorge, Jorgensen, Helle F., Carobbio, Stefania, Vidal-Puig, Antonio, McKenzie, Andrew N.J.
Publicado 2019

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33

por Osbourn, Megan, Soares, Dinesh C., Vacca, Francesco, Cohen, E. Suzanne, Scott, Ian C., Gregory, William F., Smyth, Danielle J., Toivakka, Matilda, Kemter, Andrea M., le Bihan, Thierry, Wear, Martin, Hoving, Dennis, Filbey, Kara J., Hewitson, James P., Henderson, Holly, Gonzàlez-Cìscar, Andrea, Errington, Claire, Vermeren, Sonja, Astier, Anne L., Wallace, William A., Schwarze, Jürgen, Ivens, Alasdair C., Maizels, Rick M., McSorley, Henry J.
Publicado 2017

Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction

por England, Elizabeth, Rees, D. Gareth, Scott, Ian Christopher, Carmen, Sara, Chan, Denice T. Y., Chaillan Huntington, Catherine E., Houslay, Kirsty F., Erngren, Teodor, Penney, Mark, Majithiya, Jayesh B., Rapley, Laura, Sims, Dorothy A., Hollins, Claire, Hinchy, Elizabeth C., Strain, Martin D., Kemp, Benjamin P., Corkill, Dominic J., May, Richard D., Vousden, Katherine A., Butler, Robin J., Mustelin, Tomas, Vaughan, Tristan J., Lowe, David C., Colley, Caroline, Cohen, E. Suzanne
Publicado 2023

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex

por Strickson, Sam, Houslay, Kirsty F., Negri, Victor A., Ohne, Yoichiro, Ottosson, Tomas, Dodd, Roger B., Huntington, Catherine Chaillan, Baker, Tina, Li, Jingjing, Stephenson, Katherine E., O'Connor, Andy J., Sagawe, J. Sophie, Killick, Helen, Moore, Tom, Rees, D. Gareth, Koch, Sofia, Sanden, Caroline, Wang, Yixin, Gubbins, Elise, Ghaedi, Mahboobe, Kolbeck, Roland, Saumyaa, Saumyaa, Erjefält, Jonas S., Sims, Gary P., Humbles, Alison A., Scott, Ian C., Romero Ros, Xavier, Cohen, E. Suzanne
Publicado 2023

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation

por Cohen, E. Suzanne, Scott, Ian C., Majithiya, Jayesh B., Rapley, Laura, Kemp, Benjamin P., England, Elizabeth, Rees, D. Gareth, Overed-Sayer, Catherine L., Woods, Joanne, Bond, Nicholas J., Veyssier, Christel Séguy, Embrey, Kevin J., Sims, Dorothy A., Snaith, Michael R., Vousden, Katherine A., Strain, Martin D., Chan, Denice T. Y., Carmen, Sara, Huntington, Catherine E., Flavell, Liz, Xu, Jianqing, Popovic, Bojana, Brightling, Christopher E., Vaughan, Tristan J., Butler, Robin, Lowe, David C., Higazi, Daniel R., Corkill, Dominic J., May, Richard D., Sleeman, Matthew A., Mustelin, Tomas
Publicado 2015