Evolving treatment paradigms in recurrent and metastatic head and neck squamous cell carcinoma: the emergence of immunotherapy

por Faraji, Farhoud, Cohen, Ezra E. W., Guo, Theresa W.
Publicado 2023

Current perspectives on recurrent HPV-mediated oropharyngeal cancer

por Guo, Theresa, Kang, Stephen Y., Cohen, Ezra E. W.
Publicado 2022

Hereditary oral squamous cell carcinoma associated with CDKN2A germline mutation: a case report

por Jeong, Ah-Reum, Forbes, Kimberly, Orosco, Ryan K., Cohen, Ezra E. W.
Publicado 2022

Defining the Role of Immunotherapy in the Curative Treatment of Locoregionally Advanced Head and Neck Cancer: Promises, Challenges, and Opportunities

por Saddawi-Konefka, Robert, Simon, Aaron B., Sumner, Whitney, Sharabi, Andrew, Mell, Loren K., Cohen, Ezra E. W.
Publicado 2021

Pan-Cancer Analysis of Patient Tumor Single-Cell Transcriptomes Identifies Promising Selective and Safe Chimeric Antigen Receptor Targets in Head and Neck Cancer

por Madan, Sanna, Sinha, Sanju, Chang, Tiangen, Gutkind, J. Silvio, Cohen, Ezra E. W., Schäffer, Alejandro A., Ruppin, Eytan
Publicado 2023

A Novel Peptide for Simultaneously Enhanced Treatment of Head and Neck Cancer and Mitigation of Oral Mucositis

por Chen, Peili, Mancini, Maria, Sonis, Stephen T., Fernandez-Martinez, Juan, Liu, Jing, Cohen, Ezra E. W., Toback, F. Gary
Publicado 2016

p62/SQSTM1 Accumulation in Squamous Cell Carcinoma of Head and Neck Predicts Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitors

por Kuo, Wen-Liang, Sharifi, Marina N., Lingen, Mark W., Ahmed, Omar, Liu, Jing, Nagilla, Madhavi, Macleod, Kay F., Cohen, Ezra E. W.
Publicado 2014

Next generation sequencing of cell free circulating tumor DNA in blood samples of recurrent and metastatic head and neck cancer patients

por Porter, Ashleigh, Natsuhara, Mandy, Daniels, Gregory A., Patel, Sandip Pravin, Sacco, Assuntina Gesualda, Bykowski, Julie, Banks, Kimberly C., Cohen, Ezra E. W.
Publicado 2020

Single Sample Expression-Anchored Mechanisms Predict Survival in Head and Neck Cancer

por Yang, Xinan, Regan, Kelly, Huang, Yong, Zhang, Qingbei, Li, Jianrong, Seiwert, Tanguy Y., Cohen, Ezra E. W., Xing, H. Rosie, Lussier, Yves A.
Publicado 2012

Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo

por Young, Natalie R., Soneru, Christian, Liu, Jing, Grushko, Tatyana A., Hardeman, Ashley, Olopade, Olufunmilayo I., Baum, Anke, Solca, Flavio, Cohen, Ezra E. W.
Publicado 2015

A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy

por Guram, Kripa, Kim, Sangwoo S., Wu, Victoria, Sanders, P. Dominick, Patel, Sandip, Schoenberger, Stephen P., Cohen, Ezra E. W., Chen, Si-Yi, Sharabi, Andrew B.
Publicado 2019

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA(+) oral cancers

por Yamaguchi, Kosuke, Iglesias-Bartolomé, Ramiro, Wang, Zhiyong, Callejas-Valera, Juan Luis, Amornphimoltham, Panomwat, Molinolo, Alfredo A., Cohen, Ezra E., Califano, Joseph A., Lippman, Scott M., Luo, Ji, Gutkind, J. Silvio
Publicado 2016

Method for estimation of apoptotic cell fraction of cytotherapy using in vivo fluorine-19 magnetic resonance: pilot study in a patient with head and neck carcinoma receiving tumor-...

por Ahrens, Eric T, Helfer, Brooke M, O’Hanlon, Charles F, Lister, Deanne R, Bykowski, Julie L, Messer, Karen, Leach, Benjamin I, Chen, Jiawen, Xu, Hongyan, Daniels, Gregory A, Cohen, Ezra E W
Publicado 2023

Programmed death 1 (PD‐1) and ligand (PD‐L1) inhibitors in head and neck squamous cell carcinoma: A meta‐analysis

por Levy, Dylan A., Patel, Jaimin J., Nguyen, Shaun A., Nicholas Jungbauer, W., Neskey, David M., Cohen, Ezra E. W., Paulos, Chrystal M., Kaczmar, John A., Knochelmann, Hannah M., Day, Terry A.
Publicado 2022

Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize

por Adams, Stephen R., Yang, Howard C., Savariar, Elamprakash N., Aguilera, Joe, Crisp, Jessica L., Jones, Karra A., Whitney, Michael A., Lippman, Scott M., Cohen, Ezra E. W., Tsien, Roger Y., Advani, Sunil J.
Publicado 2016

Tumor cells fail to present MHC-II–restricted epitopes derived from oncogenes to CD4(+) T cells

por Brightman, Spencer E., Naradikian, Martin S., Thota, Rukman R., Becker, Angelica, Montero, Leslie, Bahmanof, Milad, Premlal, Ashmitaa Logandha Ramamoorthy, Greenbaum, Jason A., Peters, Bjoern, Cohen, Ezra E.W., Miller, Aaron M., Schoenberger, Stephen P.
Publicado 2023

A phase Ib study of utomilumab (PF-05082566) in combination with mogamulizumab in patients with advanced solid tumors

por Cohen, Ezra E. W., Pishvaian, Michael J., Shepard, Dale R., Wang, Ding, Weiss, Jared, Johnson, Melissa L., Chung, Christine H., Chen, Ying, Huang, Bo, Davis, Craig B., Toffalorio, Francesca, Thall, Aron, Powell, Steven F.
Publicado 2019

Somatic 9p24.1 alterations in HPV(–) head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity

por Zhao, Xin, Cohen, Ezra E. W., William, William N., Bianchi, Joy J., Abraham, Jim P., Magee, Daniel, Spetzler, David B., Gutkind, J. Silvio, Alexandrov, Ludmil B., Cavenee, Webster K., Lippman, Scott M., Davoli, Teresa
Publicado 2022

Author Correction: Neoantigen-specific stem cell memory-like CD4(+) T cells mediate CD8(+) T cell-dependent immunotherapy of MHC class II-negative solid tumors

por Brightman, Spencer E., Becker, Angelica, Thota, Rukman R., Naradikian, Martin S., Chihab, Leila, Zavala, Karla Soria, Ramamoorthy Premlal, Ashmitaa Logandha, Griswold, Ryan Q., Dolina, Joseph S., Cohen, Ezra E. W., Miller, Aaron M., Peters, Bjoern, Schoenberger, Stephen P.
Publicado 2023

Neoantigen-specific stem cell memory-like CD4(+) T cells mediate CD8(+) T cell-dependent immunotherapy of MHC class II-negative solid tumors

por Brightman, Spencer E., Becker, Angelica, Thota, Rukman R., Naradikian, Martin S., Chihab, Leila, Zavala, Karla Soria, Ramamoorthy Premlal, Ashmitaa Logandha, Griswold, Ryan Q., Dolina, Joseph S., Cohen, Ezra E. W., Miller, Aaron M., Peters, Bjoern, Schoenberger, Stephen P.
Publicado 2023