Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins

por Spåhr, Henrik, Chia, Tiongsun, Lingford, James P., Siira, Stefan J., Cohen, Scott B., Filipovska, Aleksandra, Rackham, Oliver
Publicado 2018

TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly

por Klump, Basma M., Perez, Gloria I., Patrick, Eric M., Adams-Boone, Kate, Cohen, Scott B., Han, Li, Yu, Kefei, Schmidt, Jens C.
Publicado 2023

Direct involvement of the TEN domain at the active site of human telomerase

por Jurczyluk, Julie, Nouwens, Amanda S., Holien, Jessica K., Adams, Timothy E., Lovrecz, George O., Parker, Michael W., Cohen, Scott B., Bryan, Tracy M.
Publicado 2011

Telomeric G-quadruplexes are a substrate and site of localization for human telomerase

por Moye, Aaron L., Porter, Karina C., Cohen, Scott B., Phan, Tram, Zyner, Katherine G., Sasaki, Natsuki, Lovrecz, George O., Beck, Jennifer L., Bryan, Tracy M.
Publicado 2015

Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension

por Porreca, Rosa M, Glousker, Galina, Awad, Aya, Matilla Fernandez, Maria I, Gibaud, Anne, Naucke, Christian, Cohen, Scott B, Bryan, Tracy M, Tzfati, Yehuda, Draskovic, Irena, Londoño-Vallejo, Arturo
Publicado 2018

Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder

por Niaz, Aram, Truong, Jia, Manoleras, Annabel, Fox, Lucy C., Blombery, Piers, Vasireddy, Raja S., Pickett, Hilda A., Curtin, Julie A., Barbaro, Pasquale M., Rodgers, Jonathan, Roy, John, Riley, Lisa G., Holien, Jessica K., Cohen, Scott B., Bryan, Tracy M.
Publicado 2022

Dephosphorylation of YB-1 is Required for Nuclear Localisation During G(2) Phase of the Cell Cycle

por Mehta, Sunali, McKinney, Cushla, Algie, Michael, Verma, Chandra S., Kannan, Srinivasaraghavan, Harfoot, Rhodri, Bartolec, Tara K., Bhatia, Puja, Fisher, Alistair J., Gould, Maree L., Parker, Kim, Cesare, Anthony J., Cunliffe, Heather E., Cohen, Scott B., Kleffmann, Torsten, Braithwaite, Antony W., Woolley, Adele G.
Publicado 2020

Prognostic Association of YB-1 Expression in Breast Cancers: A Matter of Antibody

por Woolley, Adele G., Algie, Michael, Samuel, Weini, Harfoot, Rhodri, Wiles, Anna, Hung, Noelyn A., Tan, Puay-Hoon, Hains, Peter, Valova, Valentina A., Huschtscha, Lily, Royds, Janice A., Perez, David, Yoon, Han-Seung, Cohen, Scott B., Robinson, Phillip J., Bay, Boon-Huat, Lasham, Annette, Braithwaite, Antony W.
Publicado 2011

A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution

por Paudel, Bishnu P, Moye, Aaron Lavel, Abou Assi, Hala, El-Khoury, Roberto, Cohen, Scott B, Holien, Jessica K, Birrento, Monica L, Samosorn, Siritron, Intharapichai, Kamthorn, Tomlinson, Christopher G, Teulade-Fichou, Marie-Paule, González, Carlos, Beck, Jennifer L, Damha, Masad J, van Oijen, Antoine M, Bryan, Tracy M
Publicado 2020

Critical Role for Cold Shock Protein YB-1 in Cytokinesis

por Mehta, Sunali, Algie, Michael, Al-Jabry, Tariq, McKinney, Cushla, Kannan, Srinivasaraghavan, Verma, Chandra S, Ma, Weini, Zhang, Jessie, Bartolec, Tara K., Masamsetti, V. Pragathi, Parker, Kim, Henderson, Luke, Gould, Maree L, Bhatia, Puja, Harfoot, Rhodri, Chircop, Megan, Kleffmann, Torsten, Cohen, Scott B, Woolley, Adele G, Cesare, Anthony J, Braithwaite, Antony
Publicado 2020