AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes

por Bruyneel, Arne A. N., Colas, Alexandre R., Karakikes, Ioannis, Mercola, Mark
Publicado 2019

Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling

por Schroeder, Analyne M., Nielsen, Tanja, Lynott, Michaela, Vogler, Georg, Colas, Alexandre R., Bodmer, Rolf
Publicado 2022

Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes

por Kannan, Suraj, Miyamoto, Matthew, Zhu, Renjun, Lynott, Michaela, Guo, Jason, Chen, Elaine Zhelan, Colas, Alexandre R., Lin, Brian Leei, Kwon, Chulan
Publicado 2023

Dietary Emulsifier Sodium Stearoyl Lactylate Alters Gut Microbiota in vitro and Inhibits Bacterial Butyrate Producers

por Elmén, Lisa, Zlamal, Jaime E., Scott, David A., Lee, Ryan B., Chen, Daniel J., Colas, Alexandre R., Rodionov, Dmitry A., Peterson, Scott N.
Publicado 2020

Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm

por Kervadec, Anaïs, Kezos, James, Ni, Haibo, Yu, Michael, Marchant, James, Spiering, Sean, Kannan, Suraj, Kwon, Chulan, Andersen, Peter, Bodmer, Rolf, Grandi, Eleonora, Ocorr, Karen, Colas, Alexandre R.
Publicado 2023

An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes

por McKeithan, Wesley L., Savchenko, Alex, Yu, Michael S., Cerignoli, Fabio, Bruyneel, Arne A. N., Price, Jeffery H., Colas, Alexandre R., Miller, Evan W., Cashman, John R., Mercola, Mark
Publicado 2017

Silencing of CCR4-NOT complex subunits affects heart structure and function

por Elmén, Lisa, Volpato, Claudia B., Kervadec, Anaïs, Pineda, Santiago, Kalvakuri, Sreehari, Alayari, Nakissa N., Foco, Luisa, Pramstaller, Peter P., Ocorr, Karen, Rossini, Alessandra, Cammarato, Anthony, Colas, Alexandre R., Hicks, Andrew A., Bodmer, Rolf
Publicado 2020

Genetic architecture of natural variation of cardiac performance from flies to humans

por Saha, Saswati, Spinelli, Lionel, Castro Mondragon, Jaime A, Kervadec, Anaïs, Lynott, Michaela, Kremmer, Laurent, Roder, Laurence, Krifa, Sallouha, Torres, Magali, Brun, Christine, Vogler, Georg, Bodmer, Rolf, Colas, Alexandre R, Ocorr, Karen, Perrin, Laurent
Publicado 2022

PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2

por Murphy, Sean A., Miyamoto, Matthew, Kervadec, Anaïs, Kannan, Suraj, Tampakakis, Emmanouil, Kambhampati, Sandeep, Lin, Brian Leei, Paek, Sam, Andersen, Peter, Lee, Dong-Ik, Zhu, Renjun, An, Steven S., Kass, David A., Uosaki, Hideki, Colas, Alexandre R., Kwon, Chulan
Publicado 2021

Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity

por Birker, Katja, Ge, Shuchao, Kirkland, Natalie J, Theis, Jeanne L, Marchant, James, Fogarty, Zachary C, Missinato, Maria A, Kalvakuri, Sreehari, Grossfeld, Paul, Engler, Adam J, Ocorr, Karen, Nelson, Timothy J, Colas, Alexandre R, Olson, Timothy M, Vogler, Georg, Bodmer, Rolf
Publicado 2023

Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells

por Missinato, Maria A., Murphy, Sean, Lynott, Michaela, Yu, Michael S., Kervadec, Anaïs, Chang, Yu-Ling, Kannan, Suraj, Loreti, Mafalda, Lee, Christopher, Amatya, Prashila, Tanaka, Hiroshi, Huang, Chun-Teng, Puri, Pier Lorenzo, Kwon, Chulan, Adams, Peter D., Qian, Li, Sacco, Alessandra, Andersen, Peter, Colas, Alexandre R.
Publicado 2023

Id genes are essential for early heart formation

por Cunningham, Thomas J., Yu, Michael S., McKeithan, Wesley L., Spiering, Sean, Carrette, Florent, Huang, Chun-Teng, Bushway, Paul J., Tierney, Matthew, Albini, Sonia, Giacca, Mauro, Mano, Miguel, Puri, Pier Lorenzo, Sacco, Alessandra, Ruiz-Lozano, Pilar, Riou, Jean-Francois, Umbhauer, Muriel, Duester, Gregg, Mercola, Mark, Colas, Alexandre R.
Publicado 2017

Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome

por Theis, Jeanne L, Vogler, Georg, Missinato, Maria A, Li, Xing, Nielsen, Tanja, Zeng, Xin-Xin I, Martinez-Fernandez, Almudena, Walls, Stanley M, Kervadec, Anaïs, Kezos, James N, Birker, Katja, Evans, Jared M, O'Byrne, Megan M, Fogarty, Zachary C, Terzic, André, Grossfeld, Paul, Ocorr, Karen, Nelson, Timothy J, Olson, Timothy M, Colas, Alexandre R, Bodmer, Rolf
Publicado 2020