Carnauba wax nanoparticles enhance strong systemic and mucosal cellular and humoral immune responses to HIV-gp140 antigen

por Arias, Mauricio A., Loxley, Andrew, Eatmon, Christy, Van Roey, Griet, Fairhurst, David, Mitchnick, Mark, Dash, Philip, Cole, Tom, Wegmann, Frank, Sattentau, Quentin, Shattock, Robin
Publicado 2011

Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms

por Donnelly, Louise, Curran, Rhonda M., Tregoning, John S., McKay, Paul F., Cole, Tom, Morrow, Ryan J., Kett, Vicky L., Andrews, Gavin P., Woolfson, A. David, Malcolm, R. Karl, Shattock, Robin J.
Publicado 2011

Antibody responses after intravaginal immunisation with trimeric HIV-1(CN54) clade C gp140 in Carbopol gel are augmented by systemic priming or boosting with an adjuvanted formulat...

por Cranage, Martin P., Fraser, Carol A., Cope, Alethea, McKay, Paul F., Seaman, Michael S., Cole, Tom, Mahmoud, A. Nasir, Hall, Joanna, Giles, Elaine, Voss, Gerald, Page, Mark, Almond, Neil, Shattock, Robin J.
Publicado 2011

[(18)F]Fluciclatide PET as a biomarker of response to combination therapy of pazopanib and paclitaxel in platinum-resistant/refractory ovarian cancer

por Sharma, Rohini, Valls, Pablo Oriol, Inglese, Marianna, Dubash, Suraiya, Chen, Michelle, Gabra, Hani, Montes, Ana, Challapalli, Amarnath, Arshad, Mubarik, Tharakan, George, Chambers, Ed, Cole, Tom, Lozano-Kuehne, Jingky P., Barwick, Tara D., Aboagye, Eric O.
Publicado 2019

Phase I Randomised Clinical Trial of an HIV-1(CN54), Clade C, Trimeric Envelope Vaccine Candidate Delivered Vaginally

por Lewis, David J., Fraser, Carol A., Mahmoud, Abdel N., Wiggins, Rebecca C., Woodrow, Maria, Cope, Alethea, Cai, Chun, Giemza, Rafaela, Jeffs, Simon A., Manoussaka, Maria, Cole, Tom, Cranage, Martin P., Shattock, Robin J., Lacey, Charles J.
Publicado 2011

PRIME-HCC: phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma

por Pinato, David J., Cortellini, Alessio, Sukumaran, Ajithkumar, Cole, Tom, Pai, Madhava, Habib, Nagy, Spalding, Duncan, Sodergren, Mikael H., Martinez, Maria, Dhillon, Tony, Tait, Paul, Thomas, Robert, Ward, Caroline, Kocher, Hemant, Yip, Vincent, Slater, Sarah, Sharma, Rohini
Publicado 2021

Enhanced immune responses following heterologous vaccination with self-amplifying RNA and mRNA COVID-19 vaccines

por Elliott, Tamara, Cheeseman, Hannah M., Evans, Abbey B., Day, Suzanne, McFarlane, Leon R., O’Hara, Jessica, Kalyan, Mohini, Amini, Fahimah, Cole, Tom, Winston, Alan, Fidler, Sarah, Pollock, Katrina M., Harker, James A., Shattock, Robin J.
Publicado 2022

Comparison of blood and lymph node cells after intramuscular injection with HIV envelope immunogens

por Day, Suzanne, Kaur, Charandeep, Cheeseman, Hannah M., de Groot, Emily, McFarlane, Leon R., Tanaka, Maniola, Coelho, Sofia, Cole, Tom, Lemm, Nana-Marie, Lim, Adrian, Sanders, Rogier W., Asquith, Becca, Shattock, Robin J., Pollock, Katrina M.
Publicado 2022

The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadl...

por Lee, Ming Jie, Collins, Simon, Babalis, Daphne, Johnson, Nicholas, Falaschetti, Emanuela, Prevost, A. Toby, Ashraf, Ambreen, Jacob, Milaana, Cole, Tom, Hurley, Lisa, Pace, Matthew, Ogbe, Ane, Khan, Maryam, Zacharopoulou, Panagiota, Brown, Helen, Sutherland, Euan, Box, Hanna, Fox, Julie, Deeks, Steven, Horowitz, Jill, Nussenzweig, Michel C., Caskey, Marina, Frater, John, Fidler, Sarah
Publicado 2022

A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost V...

por Kratochvil, Sven, McKay, Paul F., Kopycinski, Jakub T., Bishop, Cynthia, Hayes, Peter John, Muir, Luke, Pinder, Christopher L., Cizmeci, Deniz, King, Deborah, Aldon, Yoann, Wines, Bruce D., Hogarth, P. Mark, Chung, Amy W., Kent, Stephen J., Held, Kathrin, Geldmacher, Christof, Dally, Len, Santos, Nelson S., Cole, Tom, Gilmour, Jill, Fidler, Sarah, Shattock, Robin J.
Publicado 2017

Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study

por Cosgrove, Catherine A., Lacey, Charles J., Cope, Alethea V., Bartolf, Angela, Morris, Georgina, Yan, Celine, Baden, Susan, Cole, Tom, Carter, Darrick, Brodnicki, Elizabeth, Shen, Xiaoying, Joseph, Sarah, DeRosa, Stephen C., Peng, Lili, Yu, Xuesong, Ferrari, Guido, Seaman, Mike, Montefiori, David C., Frahm, Nicole, Tomaras, Georgia D., Stöhr, Wolfgang, McCormack, Sheena, Shattock, Robin J.
Publicado 2016

Combined Skin and Muscle DNA Priming Provides Enhanced Humoral Responses to a Human Immunodeficency Virus Type 1 Clade C Envelope Vaccine

por Cheeseman, Hannah Mary, Day, Suzanne, McFarlane, Leon Robert, Fleck, Sue, Miller, Aleisha, Cole, Tom, Sousa-Santos, Nelson, Cope, Alethea, Cizmeci, Deniz, Tolazzi, Monica, Hwekwete, Edith, Hannaman, Drew, Kratochvil, Sven, McKay, Paul Francis, Chung, Amy W., Kent, Stephen J., Cook, Adrian, Scarlatti, Gabriella, Abraham, Sonya, Combadiere, Behazine, McCormack, Sheena, Lewis, David John, Shattock, Robin John
Publicado 2018

Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial

por Pollock, Katrina M., Cheeseman, Hannah M., Szubert, Alexander J., Libri, Vincenzo, Boffito, Marta, Owen, David, Bern, Henry, O'Hara, Jessica, McFarlane, Leon R., Lemm, Nana-Marie, McKay, Paul F., Rampling, Tommy, Yim, Yee Ting N., Milinkovic, Ana, Kingsley, Cherry, Cole, Tom, Fagerbrink, Susanne, Aban, Marites, Tanaka, Maniola, Mehdipour, Savviz, Robbins, Alexander, Budd, William, Faust, Saul N., Hassanin, Hana, Cosgrove, Catherine A., Winston, Alan, Fidler, Sarah, Dunn, David T., McCormack, Sheena, Shattock, Robin J.
Publicado 2022

COVAC1 phase 2a expanded safety and immunogenicity study of a self-amplifying RNA vaccine against SARS-CoV-2

por Szubert, Alex J., Pollock, Katrina M., Cheeseman, Hannah M., Alagaratnam, Jasmini, Bern, Henry, Bird, Olivia, Boffito, Marta, Byrne, Ruth, Cole, Tom, Cosgrove, Catherine A., Faust, Saul N., Fidler, Sarah, Galiza, Eva, Hassanin, Hana, Kalyan, Mohini, Libri, Vincenzo, McFarlane, Leon R., Milinkovic, Ana, O'Hara, Jessica, Owen, David R., Owens, Daniel, Pacurar, Mihaela, Rampling, Tommy, Skene, Simon, Winston, Alan, Woolley, James, Yim, Yee Ting N., Dunn, David T., McCormack, Sheena, Shattock, Robin J.
Publicado 2023