2342 Protein production as an early pharmacodynamics biomarker for RNA-targeting therapies

por Self, Wade K., Schoch, Kathleen, Bollinger, James, Cole, Tracy, Kordasiewicz, Holly, Bateman, Randall, Miller, Timothy
Publicado 2018

Protein production is an early biomarker for RNA‐targeted therapies

por Self, Wade K., Schoch, Kathleen M., Alex, Jacob, Barthélemy, Nicolas, Bollinger, James G., Sato, Chihiro, Cole, Tracy, Kordasiewicz, Holly B., Swayze, Eric, Bateman, Randall J., Miller, Timothy M.
Publicado 2018

Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss

por Hernandez, Michael X., Jiang, Shan, Cole, Tracy A., Chu, Shu-Hui, Fonseca, Maria I., Fang, Melody J., Hohsfield, Lindsay A., Torres, Maria D., Green, Kim N., Wetsel, Rick A., Mortazavi, Ali, Tenner, Andrea J.
Publicado 2017

Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment

por O’Callaghan, Brennon, Hofstra, Bente, Handler, Hillary P., Kordasiewicz, Holly B., Cole, Tracy, Duvick, Lisa, Friedrich, Jillian, Rainwater, Orion, Yang, Praseuth, Benneyworth, Michael, Nichols-Meade, Tessa, Heal, Wesley, Ter Haar, Rachel, Henzler, Christine, Orr, Harry T.
Publicado 2020

SNCA genetic lowering reveals differential cognitive function of alpha-synuclein dependent on sex

por Brown, Jennifer L., Hart, Damyan W., Boyle, Gabriel E., Brown, Taylor G., LaCroix, Michael, Baraibar, Andrés M., Pelzel, Ross, Kim, Minwoo, Sherman, Mathew A., Boes, Samuel, Sung, Michelle, Cole, Tracy, Lee, Michael K., Araque, Alfonso, Lesné, Sylvain E.
Publicado 2022

α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson’s disease

por Cole, Tracy A., Zhao, Hien, Collier, Timothy J., Sandoval, Ivette, Sortwell, Caryl E., Steece-Collier, Kathy, Daley, Brian F., Booms, Alix, Lipton, Jack, Welch, Mackenzie, Berman, Melissa, Jandreski, Luke, Graham, Danielle, Weihofen, Andreas, Celano, Stephanie, Schulz, Emily, Cole-Strauss, Allyson, Luna, Esteban, Quach, Duc, Mohan, Apoorva, Bennett, C. Frank, Swayze, Eric E., Kordasiewicz, Holly B., Luk, Kelvin C., Paumier, Katrina L.
Publicado 2021

IDOL regulates systemic energy balance through control of neuronal VLDLR expression

por Lee, Stephen D., Priest, Christina, Bjursell, Mikael, Gao, Jie, Arneson, Douglas V., Ahn, In Sook, Diamante, Graciel, van Veen, J. Edward, Massa, Megan G., Calkin, Anna C., Kim, Jason, Andersén, Harriet, Rajbhandari, Prashant, Porritt, Michelle, Carreras, Alba, Ahnmark, Andrea, Seeliger, Frank, Maxvall, Ingela, Eliasson, Pernilla, Althage, Magnus, Åkerblad, Peter, Lindén, Daniel, Cole, Tracy A., Lee, Richard, Boyd, Helen, Bohlooly-Y, Mohammad, Correa, Stephanie M., Yang, Xia, Tontonoz, Peter, Hong, Cynthia
Publicado 2019