Designer genetically encoded voltage‐dependent calcium channel inhibitors inspired by RGK GTPases

por Colecraft, Henry M.
Publicado 2020

Primary Culture of Adult Rat Heart Myocytes

por Xu, Xianghua, Colecraft, Henry M.
Publicado 2009

Distinct RGK GTPases Differentially Use α(1)- and Auxiliary β-Binding-Dependent Mechanisms to Inhibit Ca(V)1.2/Ca(V)2.2 Channels

por Yang, Tingting, Puckerin, Akil, Colecraft, Henry M.
Publicado 2012

Differential Occurrence of Reluctant Openings in G-Protein–Inhibited N- and P/Q-Type Calcium Channels

por Colecraft, Henry M., Patil, Parag G., Yue, David T.
Publicado 2000

Sculpting ion channel functional expression with engineered ubiquitin ligases

por Kanner, Scott A, Morgenstern, Travis, Colecraft, Henry M
Publicado 2017

Development of a High-Throughput Flow Cytometry Assay to Monitor Defective Trafficking and Rescue of Long QT2 Mutant hERG Channels

por Kanner, Scott A., Jain, Ananya, Colecraft, Henry M.
Publicado 2018

Custom Distinctions in the Interaction of G-protein β Subunits with N-type (Ca(V)2.2) Versus P/Q-type (Ca(V)2.1) Calcium Channels

por Agler, Heather L., Evans, Jenafer, Colecraft, Henry M., Yue, David T.
Publicado 2003

Similar molecular determinants on Rem mediate two distinct modes of inhibition of Ca(V)1.2 channels

por Puckerin, Akil A., Chang, Donald D., Subramanyam, Prakash, Colecraft, Henry M.
Publicado 2016

A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary Ca(V)β subunits

por Morgenstern, Travis J, Park, Jinseo, Fan, Qing R, Colecraft, Henry M
Publicado 2019

Bio-Inspired Voltage-Dependent Calcium Channel Blockers

por Yang, Tingting, He, Lin-Ling, Chen, Ming, Fang, Kun, Colecraft, Henry M.
Publicado 2013

Targeted deubiquitination rescues distinct trafficking-deficient ion channelopathies

por Kanner, Scott A., Shuja, Zunaira, Choudhury, Papiya, Jain, Ananya, Colecraft, Henry M.
Publicado 2020

A Ca(V)β SH3/Guanylate Kinase Domain Interaction Regulates Multiple Properties of Voltage-gated Ca(2+) Channels

por Takahashi, Shoji X., Miriyala, Jayalakshmi, Tay, Lai Hock, Yue, David T., Colecraft, Henry M.
Publicado 2005

Cooperative and acute inhibition by multiple C-terminal motifs of L-type Ca(2+) channels

por Liu, Nan, Yang, Yaxiong, Ge, Lin, Liu, Min, Colecraft, Henry M, Liu, Xiaodong
Publicado 2017

Engineering selectivity into RGK GTPase inhibition of voltage-dependent calcium channels

por Puckerin, Akil A., Chang, Donald D., Shuja, Zunaira, Choudhury, Papiya, Scholz, Joachim, Colecraft, Henry M.
Publicado 2018

Targeted ubiquitination of sensory neuron calcium channels reduces the development of neuropathic pain

por Sun, Linlin, Tong, Chi-Kun, Morgenstern, Travis J., Zhou, Hang, Yang, Guang, Colecraft, Henry M.
Publicado 2022

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels

por Zou, Xinle, Wu, Xiaoan, Sampson, Kevin J., Colecraft, Henry M., Larsson, H. Peter, Kass, Robert S.
Publicado 2022

Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex

por Zou, Xinle, Shanmugam, Sri Karthika, Kanner, Scott A, Sampson, Kevin J, Kass, Robert S, Colecraft, Henry M
Publicado 2023

Transfer RNA-mediated restoration of potassium current and electrical correction in premature termination long-QT syndrome hERG mutants

por Blomquist, Viggo G., Niu, Jacqueline, Choudhury, Papiya, Al Saneh, Ahmad, Colecraft, Henry M., Ahern, Christopher A.
Publicado 2023

The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency

por Jenewein, Tina, Kanner, Scott A., Bauer, Daniel, Hertel, Brigitte, Colecraft, Henry M., Moroni, Anna, Thiel, Gerhard, Kauferstein, Silke
Publicado 2020

Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

por Joseph, Leroy C., Barca, Emanuele, Subramanyam, Prakash, Komrowski, Michael, Pajvani, Utpal, Colecraft, Henry M., Hirano, Michio, Morrow, John P.
Publicado 2016