Assessing hERG Pore Models As Templates for Drug Docking Using Published Experimental Constraints: The Inactivated State in the Context of Drug Block

por Dempsey, Christopher E., Wright, Dominic, Colenso, Charlotte K., Sessions, Richard B., Hancox, Jules C.
Publicado 2014

Voltage Sensor Gating Charge Transfer in a hERG Potassium Channel Model

por Colenso, Charlotte K., Cao, Yang, Sessions, Richard B., Hancox, Jules C., Dempsey, Christopher E.
Publicado 2014

The hERG K(+) channel S4 domain L532P mutation: Characterization at 37 °C

por Zhang, Yi H., Colenso, Charlotte K., Sessions, Richard B., Dempsey, Christopher E., Hancox, Jules C.
Publicado 2011

Cloning, Identification and Functional Characterization of Bovine Free Fatty Acid Receptor-1 (FFAR1/GPR40) in Neutrophils

por Manosalva, Carolina, Mena, Jaqueline, Velasquez, Zahady, Colenso, Charlotte K., Brauchi, Sebastian, Burgos, Rafael A., Hidalgo, Maria A.
Publicado 2015

Interactions between amiodarone and the hERG potassium channel pore determined with mutagenesis and in silico docking

por Zhang, Yihong, Colenso, Charlotte K., El Harchi, Aziza, Cheng, Hongwei, Witchel, Harry J., Dempsey, Chris E., Hancox, Jules C.
Publicado 2016

β-Lactamases and β-Lactamase Inhibitors in the 21st Century

por Tooke, Catherine L., Hinchliffe, Philip, Bragginton, Eilis C., Colenso, Charlotte K., Hirvonen, Viivi H.A., Takebayashi, Yuiko, Spencer, James
Publicado 2019

Evolutionary analyses reveal independent origins of gene repertoires and structural motifs associated to fast inactivation in calcium-selective TRPV channels

por Flores-Aldama, Lisandra, Vandewege, Michael W., Zavala, Kattina, Colenso, Charlotte K., Gonzalez, Wendy, Brauchi, Sebastian E., Opazo, Juan C.
Publicado 2020

Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase

por Tooke, Catherine L., Hinchliffe, Philip, Beer, Michael, Zinovjev, Kirill, Colenso, Charlotte K., Schofield, Christopher J., Mulholland, Adrian J., Spencer, James
Publicado 2023

Sequence and structural conservation reveal fingerprint residues in TRP channels

por Cabezas-Bratesco, Deny, Mcgee, Francisco A, Colenso, Charlotte K, Zavala, Kattina, Granata, Daniele, Carnevale, Vincenzo, Opazo, Juan C, Brauchi, Sebastian E
Publicado 2022