siRNA goes after diseases of the bone

por Coles, Andrew H.
Publicado 2023

MIDAS technical analysis: a VWAP approach to trading and investing in today's markets

por Coles, Andrew, Hawkins, David
Publicado 2011

Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo

por Biscans, Annabelle, Coles, Andrew, Haraszti, Reka, Echeverria, Dimas, Hassler, Matthew, Osborn, Maire, Khvorova, Anastasia
Publicado 2019

Noncanonical Wnt signaling promotes apoptosis in thymocyte development

por Liang, Huiling, Coles, Andrew H., Zhu, Zhiqing, Zayas, Jennifer, Jurecic, Roland, Kang, Joonsoo, Jones, Stephen N.
Publicado 2007

Magnitude of and Prognostic Factors Associated With 1‐Year Mortality After Hospital Discharge for Acute Decompensated Heart Failure Based on Ejection Fraction Findings

por Coles, Andrew H., Tisminetzky, Mayra, Yarzebski, Jorge, Lessard, Darleen, Gore, Joel M., Darling, Chad E., Goldberg, Robert J.
Publicado 2015

Guanabenz (Wytensin™) selectively enhances uptake and efficacy of hydrophobically modified siRNAs

por Osborn, Maire F., Alterman, Julia F., Nikan, Mehran, Cao, Hong, Didiot, Marie C., Hassler, Matthew R., Coles, Andrew H., Khvorova, Anastasia
Publicado 2015

Survival after hospital discharge for ST-segment elevation and non-ST-segment elevation acute myocardial infarction: a population-based study

por Darling, Chad E, Fisher, Kimberly A, McManus, David D, Coles, Andrew H, Spencer, Frederick A, Gore, Joel M, Goldberg, Robert J
Publicado 2013

Hdac6 regulates Tip60-p400 function in stem cells

por Chen, Poshen B, Hung, Jui-Hung, Hickman, Taylor L, Coles, Andrew H, Carey, James F, Weng, Zhiping, Chu, Feixia, Fazzio, Thomas G
Publicado 2013

5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

por Haraszti, Reka A., Roux, Loic, Coles, Andrew H., Turanov, Anton A., Alterman, Julia F., Echeverria, Dimas, Godinho, Bruno M.D.C., Aronin, Neil, Khvorova, Anastasia
Publicado 2017

Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain

por Nikan, Mehran, Osborn, Maire F, Coles, Andrew H, Godinho, Bruno MDC, Hall, Lauren M, Haraszti, Reka A, Hassler, Matthew R, Echeverria, Dimas, Aronin, Neil, Khvorova, Anastasia
Publicado 2016

Mutant huntingtin messenger RNA forms neuronal nuclear clusters in rodent and human brains

por Ly, Socheata, Didiot, Marie-Cécile, Ferguson, Chantal M, Coles, Andrew H, Miller, Rachael, Chase, Kathryn, Echeverria, Dimas, Wang, Feng, Sadri-Vakili, Ghazaleh, Aronin, Neil, Khvorova, Anastasia
Publicado 2022

Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways

por Osborn, Maire F, Coles, Andrew H, Biscans, Annabelle, Haraszti, Reka A, Roux, Loic, Davis, Sarah, Ly, Socheata, Echeverria, Dimas, Hassler, Matthew R, Godinho, Bruno M D C, Nikan, Mehran, Khvorova, Anastasia
Publicado 2019

Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain

por Alterman, Julia F, Hall, Lauren M, Coles, Andrew H, Hassler, Matthew R, Didiot, Marie-Cecile, Chase, Kathryn, Abraham, Jasmin, Sottosanti, Emily, Johnson, Emily, Sapp, Ellen, Osborn, Maire F, Difiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicado 2015

PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs

por Godinho, Bruno M.D.C., Knox, Emily G., Hildebrand, Samuel, Gilbert, James W., Echeverria, Dimas, Kennedy, Zachary, Haraszti, Reka A., Ferguson, Chantal M., Coles, Andrew H., Biscans, Annabelle, Caiazzi, Jillian, Alterman, Julia F., Hassler, Matthew R., Khvorova, Anastasia
Publicado 2022

RNAi Modulation of Placental sFLT1 for the Treatment of Preeclampsia.

por Turanov, Anton A., Lo, Agnes, Hassler, Matthew R., Makris, Angela, Ashar-Patel, Ami, Alterman, Julia F., Coles, Andrew H., Haraszti, Reka A., Roux, Loic, Godinho, Bruno MDC, Echeverria, Dimas, Pears, Suzanne, Iliopoulos, Jim, Shanmugalingam, Renuka, Ogle, Robert, Zsengeller, Zsuzsanna K., Hennessy, Annemarie, Karumanchi, S. Ananth, Moore, Melissa J., Khvorova, Anastasia
Publicado 2018

Bis-choline tetrathiomolybdate prevents copper-induced blood–brain barrier damage

por Borchard, Sabine, Raschke, Stefanie, Zak, Krzysztof M, Eberhagen, Carola, Einer, Claudia, Weber, Elisabeth, Müller, Sandra M, Michalke, Bernhard, Lichtmannegger, Josef, Wieser, Albrecht, Rieder, Tamara, Popowicz, Grzegorz M, Adamski, Jerzy, Klingenspor, Martin, Coles, Andrew H, Viana, Ruth, Vendelbo, Mikkel H, Sandahl, Thomas D, Schwerdtle, Tanja, Plitz, Thomas, Zischka, Hans
Publicado 2021

Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep

por Ferguson, Chantal M., Godinho, Bruno M.D.C., Alterman, Julia F., Coles, Andrew H., Hassler, Matthew, Echeverria, Dimas, Gilbert, James W., Knox, Emily G., Caiazzi, Jillian, Haraszti, Reka A., King, Robert M., Taghian, Toloo, Puri, Ajit, Moser, Richard P., Gounis, Matthew J., Aronin, Neil, Gray-Edwards, Heather, Khvorova, Anastasia
Publicado 2021

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

por Hassler, Matthew R, Turanov, Anton A, Alterman, Julia F, Haraszti, Reka A, Coles, Andrew H, Osborn, Maire F, Echeverria, Dimas, Nikan, Mehran, Salomon, William E, Roux, Loïc, Godinho, Bruno M D C, Davis, Sarah M, Morrissey, David V, Zamore, Phillip D, Karumanchi, S Ananth, Moore, Melissa J, Aronin, Neil, Khvorova, Anastasia
Publicado 2018

Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition

por Haraszti, Reka Agnes, Miller, Rachael, Dubuke, Michelle L., Rockwell, Hannah E., Coles, Andrew H., Sapp, Ellen, Didiot, Marie-Cecile, Echeverria, Dimas, Stoppato, Matteo, Sere, Yves Y., Leszyk, John, Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., McDaniel, Justice, Narain, Niven R., Wollacott, Rachel, Wang, Yang, Shaffer, Scott A., Kiebish, Michael A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicado 2019

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

por Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., Ferguson, Chantal M., Echeverria, Dimas, Sapp, Ellen, Haraszti, Reka A., Coles, Andrew H., Conroy, Faith, Miller, Rachael, Roux, Loic, Yan, Paul, Knox, Emily G., Turanov, Anton A., King, Robert M., Gernoux, Gwladys, Mueller, Christian, Gray-Edwards, Heather L., Moser, Richard P., Bishop, Nina C., Jaber, Samer M., Gounis, Matthew J., Sena-Esteves, Miguel, Pai, Athma A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicado 2019