Patented small molecule inhibitors in the ubiquitin proteasome system

por Guédat, Philippe, Colland, Frédéric
Publicado 2007

The disintegrin and metalloproteinase ADAM12 contributes to TGF-β signaling through interaction with the type II receptor

por Atfi, Azeddine, Dumont, Emmanuelle, Colland, Frédéric, Bonnier, Dominique, L'Helgoualc'h, Annie, Prunier, Céline, Ferrand, Nathalie, Clément, Bruno, Wewer, Ulla M., Théret, Nathalie
Publicado 2007

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling

por Arimoto, Kei-ichiro, Löchte, Sara, Stoner, Samuel A., Burkart, Christoph, Zhang, Yue, Miyauchi, Sayuri, Wilmes, Stephan, Fan, Jun-Bao, Heinisch, Jürgen J., Li, Zhi, Yan, Ming, Pellegrini, Sandra, Colland, Frédéric, Piehler, Jacob, Zhang, Dong-Er
Publicado 2017

The Effect of Core Replacement on S64315, a Selective MCL-1 Inhibitor, and Its Analogues

por Sipos, Szabolcs, Bálint, Balázs, Szabó, Zoltán B., Ondi, Levente, Csékei, Márton, Szlávik, Zoltán, Proszenyák, Ágnes, Murray, James B., Davidson, James, Chen, Ijen, Dokurno, Pawel, Surgenor, Allan E., Pedder, Christopher, Hubbard, Roderick E., Maragno, Ana-Leticia, Chanrion, Maia, Colland, Frederic, Geneste, Olivier, Kotschy, András
Publicado 2021

Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia

por Moujalled, Donia M., Pomilio, Giovanna, Ghiurau, Corina, Ivey, Adam, Salmon, Jessica, Rijal, Sewa, Macraild, Sarah, Zhang, Lan, Teh, Tse-Chieh, Tiong, Ing-Soo, Lan, Ping, Chanrion, Maia, Claperon, Audrey, Rocchetti, Francesca, Zichi, Adrien, Kraus-Berthier, Laurence, Wang, Youzhen, Halilovic, Ensar, Morris, Erick, Colland, Frédéric, Segal, David, Huang, David, Roberts, Andrew W., Maragno, Ana Leticia, Lessene, Guillaume, Geneste, Olivier, Wei, Andrew H.
Publicado 2018

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth

por Casara, Patrick, Davidson, James, Claperon, Audrey, Le Toumelin-Braizat, Gaëtane, Vogler, Meike, Bruno, Alain, Chanrion, Maïa, Lysiak-Auvity, Gaëlle, Le Diguarher, Thierry, Starck, Jérôme-Benoît, Chen, Ijen, Whitehead, Neil, Graham, Christopher, Matassova, Natalia, Dokurno, Pawel, Pedder, Christopher, Wang, Youzhen, Qiu, Shumei, Girard, Anne-Marie, Schneider, Emilie, Gravé, Fabienne, Studeny, Aurélie, Guasconi, Ghislaine, Rocchetti, Francesca, Maïga, Sophie, Henlin, Jean-Michel, Colland, Frédéric, Kraus-Berthier, Laurence, Le Gouill, Steven, Dyer, Martin J.S., Hubbard, Roderick, Wood, Mike, Amiot, Martine, Cohen, Gerald M, Hickman, John A., Morris, Erick, Murray, James, Geneste, Olivier
Publicado 2018