The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network

por Ellenbroek, Saskia I. J., Iden, Sandra, Collard, John G.
Publicado 2012

The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization

por Gérard, Audrey, Mertens, Alexander E.E., van der Kammen, Rob A., Collard, John G.
Publicado 2007

The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex

por Mertens, Alexander E.E., Rygiel, Tomasz P., Olivo, Cristina, van der Kammen, Rob, Collard, John G.
Publicado 2005

Rac Downregulates Rho Activity: Reciprocal Balance between Both Gtpases Determines Cellular Morphology and Migratory Behavior

por Sander, Eva E., ten Klooster, Jean P., van Delft, Sanne, van der Kammen, Rob A., Collard, John G.
Publicado 1999

The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho

por van Leeuwen, Frank N., Kain, Hendrie E.T., van der Kammen, Rob A., Michiels, Frits, Kranenburg, Onno W., Collard, John G.
Publicado 1997

Induction of Cell Scattering by Expression of β1 Integrins in β1-Deficient Epithelial Cells Requires Activation of Members of the Rho Family of Gtpases and Downregulation of Cadher...

por Gimond, Clotilde, van der Flier, Arjan, van Delft, Sanne, Brakebusch, Cord, Kuikman, Ingrid, Collard, John G., Fässler, Reinhard, Sonnenberg, Arnoud
Publicado 1999

Oncogenic Ras Downregulates Rac Activity, Which Leads to Increased Rho Activity and Epithelial–Mesenchymal Transition

por Zondag, Gerben C.M., Evers, Eva E., ten Klooster, Jean P., Janssen, Lennert, van der Kammen, Rob A., Collard, John G.
Publicado 2000

Matrix-dependent Tiam1/Rac Signaling in Epithelial Cells Promotes Either Cell–Cell Adhesion or Cell Migration and Is Regulated by Phosphatidylinositol 3-Kinase

por Sander, Eva E., van Delft, Sanne, ten Klooster, Jean P., Reid, Tim, van der Kammen, Rob A., Michiels, Frits, Collard, John G.
Publicado 1998

Regulated Membrane Localization of Tiam1, Mediated by the NH(2)-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH(2)-terminal Kinase...

por Michiels, Frits, Stam, Jord C., Hordijk, Peter L., van der Kammen, Rob A., Stalle, Lisette Ruuls-Van, Feltkamp, Constance A., Collard, John G.
Publicado 1997

The Rac activator Tiam1 is required for α3β1-mediated laminin-5 deposition, cell spreading, and cell migration

por Hamelers, Irene H.L., Olivo, Cristina, Mertens, Alexander E.E., Pegtel, D. Michiel, van der Kammen, Rob A., Sonnenberg, Arnoud, Collard, John G.
Publicado 2005

Role of the Pi3k Regulatory Subunit in the Control of Actin Organization and Cell Migration

por Jiménez, Concepción, Portela, Rosario Armas, Mellado, Mario, Rodríguez-Frade, Jose Miguel, Collard, John, Serrano, Antonio, Martínez-A, Carlos, Avila, Jesus, Carrera, Ana C.
Publicado 2000

Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration

por Wang, Shujie, Watanabe, Takashi, Matsuzawa, Kenji, Katsumi, Akira, Kakeno, Mai, Matsui, Toshinori, Ye, Feng, Sato, Kazuhide, Murase, Kiyoko, Sugiyama, Ikuko, Kimura, Kazushi, Mizoguchi, Akira, Ginsberg, Mark H., Collard, John G., Kaibuchi, Kozo
Publicado 2012