Arrhythmia mechanisms and spontaneous calcium release: Bi-directional coupling between re-entrant and focal excitation

por Colman, Michael A.
Publicado 2019

A simple approach for image-based modelling of the heart that enables robust simulation of highly heterogeneous electrical excitation

por Colman, Michael A., Benson, Alan P.
Publicado 2023

Description of the Human Atrial Action Potential Derived From a Single, Congruent Data Source: Novel Computational Models for Integrated Experimental-Numerical Study of Atrial Arrh...

por Colman, Michael A., Saxena, Priyanka, Kettlewell, Sarah, Workman, Antony J.
Publicado 2018

Filter preconditioning enables representative scaled-down modelling of filter capacity and viral clearance by mitigating the impact of virus spike impurities

por Khan, Navid Z., Parrella, Joseph J., Genest, Paul W., Colman, Michael S.
Publicado 2009

Atrial Heterogeneity Generates Re-entrant Substrate during Atrial Fibrillation and Anti-arrhythmic Drug Action: Mechanistic Insights from Canine Atrial Models

por Varela, Marta, Colman, Michael A., Hancox, Jules C., Aslanidi, Oleg V.
Publicado 2016

Novel non-invasive algorithm to identify the origins of re-entry and ectopic foci in the atria from 64-lead ECGs: A computational study

por Alday, Erick A. Perez, Colman, Michael A., Langley, Philip, Zhang, Henggui
Publicado 2017

In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis

por Colman, Michael A., Ni, Haibo, Liang, Bo, Schmitt, Nicole, Zhang, Henggui
Publicado 2017

Slow Conduction in the Border Zones of Patchy Fibrosis Stabilizes the Drivers for Atrial Fibrillation: Insights from Multi-Scale Human Atrial Modeling

por Morgan, Ross, Colman, Michael A., Chubb, Henry, Seemann, Gunnar, Aslanidi, Oleg V.
Publicado 2016

A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reco...

por Colman, Michael A., Pinali, Christian, Trafford, Andrew W., Zhang, Henggui, Kitmitto, Ashraf
Publicado 2017

Evolution and pharmacological modulation of the arrhythmogenic wave dynamics in canine pulmonary vein model

por Colman, Michael A., Varela, Marta, Hancox, Jules C., Zhang, Henggui, Aslanidi, Oleg V.
Publicado 2014

Trigger vs. Substrate: Multi-Dimensional Modulation of QT-Prolongation Associated Arrhythmic Dynamics by a hERG Channel Activator

por Colman, Michael A., Perez Alday, Erick A., Holden, Arun V., Benson, Alan P.
Publicado 2017

Human Atrial Arrhythmogenesis and Sinus Bradycardia in KCNQ1-Linked Short QT Syndrome: Insights From Computational Modelling

por Whittaker, Dominic G., Colman, Michael A., Ni, Haibo, Hancox, Jules C., Zhang, Henggui
Publicado 2018

Effects of Heart Rate and Ventricular Wall Thickness on Non-invasive Mapping: An in silico Study

por Perez Alday, Erick Andres, Whittaker, Dominic G., Benson, Alan P., Colman, Michael A.
Publicado 2019

Investigation of the Role of Myocyte Orientations in Cardiac Arrhythmia Using Image-Based Models

por Whittaker, Dominic G., Benson, Alan P., Teh, Irvin, Schneider, Jürgen E., Colman, Michael A.
Publicado 2019

Multi-Scale Computational Modeling of Spatial Calcium Handling From Nanodomain to Whole-Heart: Overview and Perspectives

por Colman, Michael A., Alvarez-Lacalle, Enrique, Echebarria, Blas, Sato, Daisuke, Sutanto, Henry, Heijman, Jordi
Publicado 2022

Ionic current changes underlying action potential repolarization responses to physiological pacing and adrenergic stimulation in adult rat ventricular myocytes

por Howlett, Luke A., Stevenson‐Cocks, Harley, Colman, Michael A., Lancaster, Matthew K., Benson, Alan P.
Publicado 2023

Comparison of Electric- and Magnetic-Cardiograms Produced by Myocardial Ischemia in Models of the Human Ventricle and Torso

por Alday, Erick A. Perez, Ni, Haibo, Zhang, Chen, Colman, Michael A., Gan, Zizhao, Zhang, Henggui
Publicado 2016

Pro-arrhythmogenic effects of atrial fibrillation-induced electrical remodelling: insights from the three-dimensional virtual human atria

por Colman, Michael A, Aslanidi, Oleg V, Kharche, Sanjay, Boyett, Mark R, Garratt, Clifford, Hancox, Jules C, Zhang, Henggui
Publicado 2013

Dynamic clamping human and rabbit atrial calcium current: narrowing I (CaL) window abolishes early afterdepolarizations

por Kettlewell, Sarah, Saxena, Priyanka, Dempster, John, Colman, Michael A., Myles, Rachel C., Smith, Godfrey L., Workman, Antony J.
Publicado 2019

A New Algorithm to Diagnose Atrial Ectopic Origin from Multi Lead ECG Systems - Insights from 3D Virtual Human Atria and Torso

por Alday, Erick A. Perez, Colman, Michael A., Langley, Philip, Butters, Timothy D., Higham, Jonathan, Workman, Antony J., Hancox, Jules C., Zhang, Henggui
Publicado 2015