Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice

por Götzl, Julia K., Colombo, Alessio-Vittorio, Fellerer, Katrin, Reifschneider, Anika, Werner, Georg, Tahirovic, Sabina, Haass, Christian, Capell, Anja
Publicado 2018

Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation

por Dominko, Kristina, Rastija, Ana, Sobocanec, Sandra, Vidatic, Lea, Meglaj, Sarah, Lovincic Babic, Andrea, Hutter-Paier, Birgit, Colombo, Alessio-Vittorio, Lichtenthaler, Stefan F., Tahirovic, Sabina, Hecimovic, Silva
Publicado 2021

Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer’s disease

por Bettegazzi, Barbara, Sebastian Monasor, Laura, Bellani, Serena, Codazzi, Franca, Restelli, Lisa Michelle, Colombo, Alessio Vittorio, Deigendesch, Nikolaus, Frank, Stephan, Saito, Takashi, Saido, Takaomi C., Lammich, Sven, Tahirovic, Sabina, Grohovaz, Fabio, Zacchetti, Daniele
Publicado 2021

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function

por Kuhn, Peer-Hendrik, Colombo, Alessio Vittorio, Schusser, Benjamin, Dreymueller, Daniela, Wetzel, Sebastian, Schepers, Ute, Herber, Julia, Ludwig, Andreas, Kremmer, Elisabeth, Montag, Dirk, Müller, Ulrike, Schweizer, Michaela, Saftig, Paul, Bräse, Stefan, Lichtenthaler, Stefan F
Publicado 2016

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

por Sebastian Monasor, Laura, Müller, Stephan A, Colombo, Alessio Vittorio, Tanrioever, Gaye, König, Jasmin, Roth, Stefan, Liesz, Arthur, Berghofer, Anna, Piechotta, Anke, Prestel, Matthias, Saito, Takashi, Saido, Takaomi C, Herms, Jochen, Willem, Michael, Haass, Christian, Lichtenthaler, Stefan F, Tahirovic, Sabina
Publicado 2020

Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism

por Götzl, Julia K, Brendel, Matthias, Werner, Georg, Parhizkar, Samira, Sebastian Monasor, Laura, Kleinberger, Gernot, Colombo, Alessio‐Vittorio, Deussing, Maximilian, Wagner, Matias, Winkelmann, Juliane, Diehl‐Schmid, Janine, Levin, Johannes, Fellerer, Katrin, Reifschneider, Anika, Bultmann, Sebastian, Bartenstein, Peter, Rominger, Axel, Tahirovic, Sabina, Smith, Scott T, Madore, Charlotte, Butovsky, Oleg, Capell, Anja, Haass, Christian
Publicado 2019

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

por Colombo, Alessio Vittorio, Sadler, Rebecca Katie, Llovera, Gemma, Singh, Vikramjeet, Roth, Stefan, Heindl, Steffanie, Sebastian Monasor, Laura, Verhoeven, Aswin, Peters, Finn, Parhizkar, Samira, Kamp, Frits, Gomez de Aguero, Mercedes, MacPherson, Andrew J, Winkler, Edith, Herms, Jochen, Benakis, Corinne, Dichgans, Martin, Steiner, Harald, Giera, Martin, Haass, Christian, Tahirovic, Sabina, Liesz, Arthur
Publicado 2021