Critical role of CD206+ macrophages in organizing anti-tumor immunity

por Ray, Arja, Hu, Kenneth H., Kersten, Kelly, Kuhn, Nicholas F., Samad, Bushra, Combes, Alexis J., Krummel, Matthew F.
Publicado 2023

Lessons of COVID-19: A roadmap for post-pandemic science

por Freedman, Tanya S., Headley, Mark B., Serwas, Nina, Ruhland, Megan, Castellanos, Carlos A., Combes, Alexis J., Krummel, Matthew F.
Publicado 2020

287 Genomic and Immunologic Characterization of Lung Adenocarcinoma in Never Smokers vs. Smokers

por Li, P. Jonathan, Tsui, Jessica, Ding, Vivianne W., Combes, Alexis J., Krummel, Matthew F., Jablons, David M., Kratz, Johannes R.
Publicado 2023

Distinct metabolic states guide maturation of inflammatory and tolerogenic dendritic cells

por Adamik, Juraj, Munson, Paul V., Hartmann, Felix J., Combes, Alexis J., Pierre, Philippe, Krummel, Matthew F., Bendall, Sean C., Argüello, Rafael J., Butterfield, Lisa H.
Publicado 2022

Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma

por Tanaka, Miho, Lum, Lotus, Hu, Kenneth, Ledezma-Soto, Cecilia, Samad, Bushra, Superville, Daphne, Ng, Kenneth, Adams, Zoe, Kersten, Kelly, Fong, Lawrence, Combes, Alexis J., Krummel, Matthew, Reeves, Melissa
Publicado 2023

Polyunsaturated Fatty Acid–Bound α-Fetoprotein Promotes Immune Suppression by Altering Human Dendritic Cell Metabolism

por Munson, Paul V., Adamik, Juraj, Hartmann, Felix J., Favaro, Patricia M.B., Ho, Daniel, Bendall, Sean C., Combes, Alexis J., Krummel, Matthew F., Zhang, Karen, Kelley, Robin K., Butterfield, Lisa H.
Publicado 2023

Genetic and immunologic features of recurrent stage I lung adenocarcinoma

por Kratz, Johannes R., Li, Jack Z., Tsui, Jessica, Lee, Jen C., Ding, Vivianne W., Rao, Arjun A., Mann, Michael J., Chan, Vincent, Combes, Alexis J., Krummel, Matthew F., Jablons, David M.
Publicado 2021

Deep immunophenotyping reveals endometriosis is marked by dysregulation of the mononuclear phagocytic system in endometrium and peripheral blood

por Vallvé-Juanico, Júlia, George, Ashley F., Sen, Sushmita, Thomas, Reuben, Shin, Min-Gyoung, Kushnoor, Divyashree, Vásquez, Joshua J., Vo, Kim Chi, Irwin, Juan C., Roan, Nadia R., Combes, Alexis J., Giudice, Linda C.
Publicado 2022

Transcriptomic analysis of immune cells in a multi-ethnic cohort of systemic lupus erythematosus patients identifies ethnicity- and disease-specific expression signatures

por Andreoletti, Gaia, Lanata, Cristina M., Trupin, Laura, Paranjpe, Ishan, Jain, Tia S., Nititham, Joanne, Taylor, Kimberly E., Combes, Alexis J., Maliskova, Lenka, Ye, Chun Jimmie, Katz, Patricia, Dall’Era, Maria, Yazdany, Jinoos, Criswell, Lindsey A., Sirota, Marina
Publicado 2021

DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells

por Cueto, Francisco J, del Fresno, Carlos, Brandi, Paola, Combes, Alexis J., Hernández-García, Elena, Sánchez-Paulete, Alfonso R, Enamorado, Michel, Bromley, Christian P, Gomez, Manuel J, Conde-Garrosa, Ruth, Mañes, Santos, Zelenay, Santiago, Melero, Ignacio, Iborra, Salvador, Krummel, Matthew F., Sancho, David
Publicado 2021

Cyclone: an accessible pipeline to analyze, evaluate, and optimize multiparametric cytometry data

por Patel, Ravi K., Jaszczak, Rebecca G., Im, Kwok, Carey, Nicholas D., Courau, Tristan, Bunis, Daniel G., Samad, Bushra, Avanesyan, Lia, Chew, Nayvin W., Stenske, Sarah, Jespersen, Jillian M., Publicover, Jean, Edwards, Austin W., Naser, Mohammad, Rao, Arjun A., Lupin-Jimenez, Leonard, Krummel, Matthew F., Cooper, Stewart, Baron, Jody L., Combes, Alexis J., Fragiadakis, Gabriela K.
Publicado 2023

SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

por Hysenaj, Lisiena, Little, Samantha, Kulhanek, Kayla, Gbenedio, Oghenekevwe M., Rodriguez, Lauren, Shen, Alan, Lone, Jean-Christophe, Lupin-Jimenez, Leonard C., Bonser, Luke R., Serwas, Nina K., Bahl, Kriti, Mick, Eran, Li, Jack Z., Ding, Vivianne W., Matsumoto, Shotaro, Maishan, Mazharul, Simoneau, Camille, Fragiadakis, Gabriela, Jablons, David M., Langelier, Charles R., Matthay, Michael, Ott, Melanie, Krummel, Matthew, Combes, Alexis J., Sil, Anita, Erle, David J., Kratz, Johannes R., Roose, Jeroen P.
Publicado 2021

Global Absence and Targeting of Protective Immune States in Severe COVID-19.

por Combes, Alexis J., Courau, Tristan, Kuhn, Nicholas F., Hu, Kenneth H., Ray, Arja, Chen, William S., Cleary, Simon J., Chew, Nayvin W., Kushnoor, Divyashree, Reeder, Gabriella C., Shen, Alan, Tsui, Jessica, Hiam-Galvez, Kamir J., Muñoz-Sandoval, Priscila, Zhu, Wandi S, Lee, David S., Sun, Yang, You, Ran, Magnen, Mélia, Rodriguez, Lauren, Leligdowicz, Aleksandra, Zamecnik, Colin R., Loudermilk, Rita P., Wilson, Michael R., Ye, Chun J., Fragiadakis, Gabriela K., Looney, Mark R., Chan, Vincent, Ward, Alyssa, Carrillo, Sidney, Matthay, Michael, Erle, David J., Woodruff, Prescott G., Langelier, Charles, Kangelaris, Kirsten, Hendrickson, Carolyn M., Calfee, Carolyn, Rao, Arjun Arkal, Krummel, Matthew F.
Publicado 2020

Publisher Correction: Global absence and targeting of protective immune states in severe COVID-19

por Combes, Alexis J., Courau, Tristan, Kuhn, Nicholas F., Hu, Kenneth H., Ray, Arja, Chen, William S., Chew, Nayvin W., Cleary, Simon J., Kushnoor, Divyashree, Reeder, Gabriella C., Shen, Alan, Tsui, Jessica, Hiam-Galvez, Kamir J., Muñoz-Sandoval, Priscila, Zhu, Wandi S., Lee, David S., Sun, Yang, You, Ran, Magnen, Mélia, Rodriguez, Lauren, Im, K. W., Serwas, Nina K., Leligdowicz, Aleksandra, Zamecnik, Colin R., Loudermilk, Rita P., Wilson, Michael R., Ye, Chun J., Fragiadakis, Gabriela K., Looney, Mark R., Chan, Vincent, Ward, Alyssa, Carrillo, Sidney, Matthay, Michael, Erle, David J., Woodruff, Prescott G., Langelier, Charles, Kangelaris, Kirsten, Hendrickson, Carolyn M., Calfee, Carolyn, Rao, Arjun Arkal, Krummel, Matthew F.
Publicado 2021

SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants

por Hysenaj, Lisiena, Little, Samantha, Kulhanek, Kayla, Magnen, Melia, Bahl, Kriti, Gbenedio, Oghenekevwe M., Prinz, Morgan, Rodriguez, Lauren, Andersen, Christopher, Rao, Arjun Arkal, Shen, Alan, Lone, Jean-Christophe, Lupin-Jimenez, Leonard C., Bonser, Luke R., Serwas, Nina K., Mick, Eran, Khalid, Mir M., Taha, Taha Y., Kumar, Renuka, Li, Jack Z., Ding, Vivianne W., Matsumoto, Shotaro, Maishan, Mazharul, Sreekumar, Bharath, Simoneau, Camille, Nazarenko, Irina, Tomlinson, Michael G., Khan, Khajida, von Gottberg, Anne, Sigal, Alex, Looney, Mark R., Fragiadakis, Gabriela K., Jablons, David M., Langelier, Charles R., Matthay, Michael, Krummel, Matthew, Erle, David J., Combes, Alexis J., Sil, Anita, Ott, Melanie, Kratz, Johannes R., Roose, Jeroen P.
Publicado 2023

Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19: Anti-IFN antibodies in critical COVID...

por van der Wijst, Monique G.P., Vazquez, Sara E., Hartoularos, George C., Bastard, Paul, Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Mann, Sabrina A., Lynch, Kara L., Yun, Cassandra, Havlir, Diane V., Chamie, Gabriel, Marquez, Carina, Greenhouse, Bryan, Lionakis, Michail S., Norris, Philip J., Dumont, Larry J., Kelly, Kathleen, Zhang, Peng, Zhang, Qian, Gervais, Adrian, Le Voyer, Tom, Whatley, Alexander, Si, Yichen, Byrne, Ashley, Combes, Alexis J., Rao, Arjun Arkal, Song, Yun S., Fragiadakis, Gabriela K., Kangelaris, Kirsten, Calfee, Carolyn S., Erle, David J., Hendrickson, Carolyn, Krummel, Matthew F., Woodruff, Prescott G., Langelier, Charles R., Casanova, Jean-Laurent, Derisi, Joseph L., Anderson, Mark S., Ye, Chun Jimmie
Publicado 2021

Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19

por van der Wijst, Monique G. P., Vazquez, Sara E., Hartoularos, George C., Bastard, Paul, Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Mann, Sabrina A., Lynch, Kara L., Yun, Cassandra, Havlir, Diane V., Chamie, Gabriel, Marquez, Carina, Greenhouse, Bryan, Lionakis, Michail S., Norris, Philip J., Dumont, Larry J., Kelly, Kathleen, Zhang, Peng, Zhang, Qian, Gervais, Adrian, Le Voyer, Tom, Whatley, Alexander, Si, Yichen, Byrne, Ashley, Combes, Alexis J., Rao, Arjun Arkal, Song, Yun S., Fragiadakis, Gabriela K., Kangelaris, Kirsten, Calfee, Carolyn S., Erle, David J., Hendrickson, Carolyn, Krummel, Matthew F., Woodruff, Prescott G., Langelier, Charles R., Casanova, Jean-Laurent, Derisi, Joseph L., Anderson, Mark S., Ye, Chun Jimmie
Publicado 2021

A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling

por Hackney, Jason A., Shivram, Haridha, Vander Heiden, Jason, Overall, Chris, Orozco, Luz, Gao, Xia, Kim, Eugene, West, Nathan, Qamra, Aditi, Chang, Diana, Chakrabarti, Arindam, Choy, David F., Combes, Alexis J., Courau, Tristan, Fragiadakis, Gabriela K., Rao, Arjun Arkal, Ray, Arja, Tsui, Jessica, Hu, Kenneth, Kuhn, Nicholas F., Krummel, Matthew F., Erle, David J., Kangelaris, Kirsten, Sarma, Aartik, Lyon, Zoe, Calfee, Carolyn S., Woodruff, Prescott G., Ghale, Rajani, Mick, Eran, Byrne, Ashley, Zha, Beth Shoshana, Langelier, Charles, Hendrickson, Carolyn M., van der Wijst, Monique G.P., Hartoularos, George C., Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Ye, Chun Jimmie, Ramalingam, Thiru, McBride, Jacqueline M., Cai, Fang, Teterina, Anastasia, Bao, Min, Tsai, Larry, Rosas, Ivan O., Regev, Aviv, Kapadia, Sharookh B., Bauer, Rebecca N., Rosenberger, Carrie M.
Publicado 2023