Transcriptional regulatory mechanisms in adipose and muscle tissue associate with composite gluco-metabolic phenotypes

por Langefeld, Carl D., Comeau, Mary E., Sharma, Neeraj K., Bowden, Donald W., Freedman, Barry I., Das, Swapan K.
Publicado 2018

Alzheimer’s disease related single nucleotide polymorphisms and correlation with intracerebral hemorrhage incidence

por Sawyer, Russell P., Demel, Stacie L., Comeau, Mary E., Marion, Miranda, Rosand, Jonathan, Langefeld, Carl D., Woo, Daniel
Publicado 2022

Social Determinants of Health and Cerebral Small Vessel Disease: Is Epigenetics a Key Mediator?

por Parodi, Livia, Mayerhofer, Ernst, Narasimhalu, Kaavya, Yechoor, Nirupama, Comeau, Mary E., Rosand, Jonathan, Langefeld, Carl D., Anderson, Christopher D.
Publicado 2023

Genetic Regulation of Enoyl-CoA Hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans

por Sharma, Neeraj K., Chuang Key, Chia-Chi, Civelek, Mete, Wabitsch, Martin, Comeau, Mary E., Langefeld, Carl D., Parks, John S., Das, Swapan K.
Publicado 2019

COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection

por Wang, Yuxuan, Guga, Suri, Wu, Kejia, Khaw, Zoe, Tzoumkas, Konstantinos, Tombleson, Phil, Comeau, Mary E., Langefeld, Carl D., Cunninghame Graham, Deborah S., Morris, David L., Vyse, Timothy J.
Publicado 2022

Systemic inflammatory response syndrome, infection, and outcome in intracerebral hemorrhage

por Boehme, Amelia K., Comeau, Mary E., Langefeld, Carl D., Lord, Aaron, Moomaw, Charles J., Osborne, Jennifer, James, Michael L., Martini, Sharyl, Testai, Fernando D., Woo, Daniel, Elkind, Mitchell S.V.
Publicado 2017

Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis

por Anderson, Warren D., Soh, Joon Yuhl, Innis, Sarah E., Dimanche, Alexis, Ma, Lijiang, Langefeld, Carl D., Comeau, Mary E., Das, Swapan K., Schadt, Eric E., Björkegren, Johan L.M., Civelek, Mete
Publicado 2020

Differential Effects of MYH9 and APOL1 Risk Variants on FRMD3 Association with Diabetic ESRD in African Americans

por Freedman, Barry I., Langefeld, Carl D., Lu, Lingyi, Divers, Jasmin, Comeau, Mary E., Kopp, Jeffrey B., Winkler, Cheryl A., Nelson, George W., Johnson, Randall C., Palmer, Nicholette D., Hicks, Pamela J., Bostrom, Meredith A., Cooke, Jessica N., McDonough, Caitrin W., Bowden, Donald W.
Publicado 2011

Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks

por Martínez-Bueno, Manuel, Oparina, Nina, Dozmorov, Mikhail G., Marion, Miranda C., Comeau, Mary E., Gilkeson, Gary, Kamen, Diane, Weisman, Michael, Salmon, Jane, McCune, Joseph W., Harley, John B., Kimberly, Robert, James, Judith A., Merrill, Joan, Montgomery, Courtney, Langefeld, Carl D., Alarcón-Riquelme, Marta E.
Publicado 2018

Metabolomic architecture of obesity implicates metabolonic lactone sulfate in cardiometabolic disease

por Das, Swapan K., Ainsworth, Hannah C., Dimitrov, Latchezar, Okut, Hayrettin, Comeau, Mary E., Sharma, Neeraj, Ng, Maggie C.Y., Norris, Jill M., Chen, Yii-der I., Wagenknecht, Lynne E., Bowden, Donald W., Hsu, Fang-Chi, Taylor, Kent D., Langefeld, Carl D., Palmer, Nicholette D.
Publicado 2021

Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans

por Lipkowitz, Michael S., Freedman, Barry I., Langefeld, Carl D., Comeau, Mary E., Bowden, Donald W., Kao, W.H. Linda, Astor, Brad C., Bottinger, Erwin P., Iyengar, Sudha K., Klotman, Paul E., Freedman, Richard G., Zhang, Weijia, Parekh, Rulan S., Choi, Michael J., Nelson, George W., Winkler, Cheryl A., Kopp, Jeffrey B.
Publicado 2012

A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

por Ramos, Paula S., Criswell, Lindsey A., Moser, Kathy L., Comeau, Mary E., Williams, Adrienne H., Pajewski, Nicholas M., Chung, Sharon A., Graham, Robert R., Zidovetzki, Raphael, Kelly, Jennifer A., Kaufman, Kenneth M., Jacob, Chaim O., Vyse, Timothy J., Tsao, Betty P., Kimberly, Robert P., Gaffney, Patrick M., Alarcón-Riquelme, Marta E., Harley, John B., Langefeld, Carl D.
Publicado 2011

Risk Factors Associated With Mortality and Neurologic Disability After Intracerebral Hemorrhage in a Racially and Ethnically Diverse Cohort

por Woo, Daniel, Comeau, Mary E., Venema, Simone Uniken, Anderson, Christopher D., Flaherty, Matthew, Testai, Fernando, Kittner, Steven, Frankel, Michael, James, Michael L., Sung, Gene, Elkind, Mitchell, Worrall, Bradford, Kidwell, Chelsea, Gonzales, Nicole, Koch, Sebastian, Hall, Christiana, Birnbaum, Lee, Mayson, Douglas, Coull, Bruce, Malkoff, Marc, Sheth, Kevin N., McCauley, Jacob L., Osborne, Jennifer, Morgan, Misty, Gilkerson, Lee, Behymer, Tyler, Coleman, Elisheva R., Rosand, Jonathan, Sekar, Padmini, Moomaw, Charles J., Langefeld, Carl D.
Publicado 2022

Brief Report: The Genetic Profile of Rheumatoid Factor–Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis

por Hinks, Anne, Marion, Miranda C., Cobb, Joanna, Comeau, Mary E., Sudman, Marc, Ainsworth, Hannah C., Bowes, John, Becker, Mara L., Bohnsack, John F., Haas, Johannes‐Peter, Lovell, Daniel J., Mellins, Elizabeth D., Nelson, J. Lee, Nordal, Ellen, Punaro, Marilynn, Reed, Ann M., Rose, Carlos D., Rosenberg, Alan M., Rygg, Marite, Smith, Samantha L., Stevens, Anne M., Videm, Vibeke, Wallace, Carol A., Wedderburn, Lucy R., Yarwood, Annie, Yeung, Rae S. M., Langefeld, Carl D., Thompson, Susan D., Thomson, Wendy, Prahalad, Sampath
Publicado 2018

Ethnic and Racial Variation in Intracerebral Hemorrhage Risk Factors and Risk Factor Burden

por Kittner, Steven J., Sekar, Padmini, Comeau, Mary E., Anderson, Christopher D., Parikh, Gunjan Y., Tavarez, Tachira, Flaherty, Matthew L., Testai, Fernando D., Frankel, Michael R., James, Michael L., Sung, Gene, Elkind, Mitchell S. V., Worrall, Bradford B., Kidwell, Chelsea S., Gonzales, Nicole R., Koch, Sebastian, Hall, Christiana E., Birnbaum, Lee, Mayson, Douglas, Coull, Bruce, Malkoff, Marc D., Sheth, Kevin N., McCauley, Jacob L., Osborne, Jennifer, Morgan, Misty, Gilkerson, Lee A., Behymer, Tyler P., Demel, Stacie L., Moomaw, Charles J., Rosand, Jonathan, Langefeld, Carl D., Woo, Daniel
Publicado 2021

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

por Hinks, Anne, Cobb, Joanna, Marion, Miranda C., Prahalad, Sampath, Sudman, Marc, Bowes, John, Martin, Paul, Comeau, Mary E., Sajuthi, Satria, Andrews, Robert, Brown, Milton, Chen, Wei-Min, Concannon, Patrick, Deloukas, Panos, Edkins, Sarah, Eyre, Stephen, Gaffney, Patrick M., Guthery, Stephen L., Guthridge, Joel M., Hunt, Sarah E., James, Judith A., Keddache, Mehdi, Moser, Kathy L., Nigrovic, Peter A., Onengut-Gumuscu, Suna, Onslow, Mitchell L., Rosé, Carlos D., Rich, Stephen S., Steel, Kathryn J.A., Wakeland, Edward K., Wallace, Carol A., Wedderburn, Lucy R., Woo, Patricia, Bohnsack, John F., Haas, Johannes Peter, Glass, David N., Langefeld, Carl D., Thomson, Wendy, Thompson, Susan D.
Publicado 2013

Lupus risk variants in the PXK locus alter B-cell receptor internalization

por Vaughn, Samuel E., Foley, Corinne, Lu, Xiaoming, Patel, Zubin H., Zoller, Erin E., Magnusen, Albert F., Williams, Adrienne H., Ziegler, Julie T., Comeau, Mary E., Marion, Miranda C., Glenn, Stuart B., Adler, Adam, Shen, Nan, Nath, Swapan, Stevens, Anne M., Freedman, Barry I., Tsao, Betty P., Jacob, Chaim O., Kamen, Diane L., Brown, Elizabeth E., Gilkeson, Gary S., Alarcón, Graciela S., Reveille, John D., Anaya, Juan-Manuel, James, Judith A., Moser, Kathy L., Criswell, Lindsey A., Vilá, Luis M., Alarcón-Riquelme, Marta E., Petri, Michelle, Scofield, R. Hal, Kimberly, Robert P., Ramsey-Goldman, Rosalind, Binjoo, Young, Choi, Jeongim, Bae, Sang-Cheol, Boackle, Susan A., Vyse, Timothy J., Guthridge, Joel M., Namjou, Bahram, Gaffney, Patrick M., Langefeld, Carl D., Kaufman, Kenneth M., Kelly, Jennifer A., Harley, Isaac T. W., Harley, John B., Kottyan, Leah C.
Publicado 2015

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA

por Zhao, Jian, Giles, Brendan M, Taylor, Rhonda L, Yette, Gabriel A, Lough, Kara M, Ng, Han Leng, Abraham, Lawrence J, Wu, Hui, Kelly, Jennifer A, Glenn, Stuart B, Adler, Adam J, Williams, Adrienne H, Comeau, Mary E, Ziegler, Julie T, Marion, Miranda, Alarcón-Riquelme, Marta E, Alarcón, Graciela S, Anaya, Juan-Manuel, Bae, Sang-Cheol, Kim, Dam, Lee, Hye-Soon, Criswell, Lindsey A, Freedman, Barry I, Gilkeson, Gary S, Guthridge, Joel M, Jacob, Chaim O, James, Judith A, Kamen, Diane L, Merrill, Joan T, Sivils, Kathy Moser, Niewold, Timothy B, Petri, Michelle A, Ramsey-Goldman, Rosalind, Reveille, John D, Scofield, R Hal, Stevens, Anne M, Vilá, Luis M, Vyse, Timothy J, Kaufman, Kenneth M, Harley, John B, Langefeld, Carl D, Gaffney, Patrick M, Brown, Elizabeth E, Edberg, Jeffrey C, Kimberly, Robert P, Ulgiati, Daniela, Tsao, Betty P, Boackle, Susan A
Publicado 2016

Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

por Zhao, Jian, Wu, Hui, Khosravi, Melanie, Cui, Huijuan, Qian, Xiaoxia, Kelly, Jennifer A., Kaufman, Kenneth M., Langefeld, Carl D., Williams, Adrienne H., Comeau, Mary E., Ziegler, Julie T., Marion, Miranda C., Adler, Adam, Glenn, Stuart B., Alarcón-Riquelme, Marta E., Pons-Estel, Bernardo A., Harley, John B., Bae, Sang-Cheol, Bang, So-Young, Cho, Soo-Kyung, Jacob, Chaim O., Vyse, Timothy J., Niewold, Timothy B., Gaffney, Patrick M., Moser, Kathy L., Kimberly, Robert P., Edberg, Jeffrey C., Brown, Elizabeth E., Alarcon, Graciela S., Petri, Michelle A., Ramsey-Goldman, Rosalind, Vilá, Luis M., Reveille, John D., James, Judith A., Gilkeson, Gary S., Kamen, Diane L., Freedman, Barry I., Anaya, Juan-Manuel, Merrill, Joan T., Criswell, Lindsey A., Scofield, R. Hal, Stevens, Anne M., Guthridge, Joel M., Chang, Deh-Ming, Song, Yeong Wook, Park, Ji Ah, Lee, Eun Young, Boackle, Susan A., Grossman, Jennifer M., Hahn, Bevra H., Goodship, Timothy H. J., Cantor, Rita M., Yu, Chack-Yung, Shen, Nan, Tsao, Betty P.
Publicado 2011

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

por Iyengar, Sudha K., Sedor, John R., Freedman, Barry I., Kao, W. H. Linda, Kretzler, Matthias, Keller, Benjamin J., Abboud, Hanna E., Adler, Sharon G., Best, Lyle G., Bowden, Donald W., Burlock, Allison, Chen, Yii-Der Ida, Cole, Shelley A., Comeau, Mary E., Curtis, Jeffrey M., Divers, Jasmin, Drechsler, Christiane, Duggirala, Ravi, Elston, Robert C., Guo, Xiuqing, Huang, Huateng, Hoffmann, Michael Marcus, Howard, Barbara V., Ipp, Eli, Kimmel, Paul L., Klag, Michael J., Knowler, William C., Kohn, Orly F., Leak, Tennille S., Leehey, David J., Li, Man, Malhotra, Alka, März, Winfried, Nair, Viji, Nelson, Robert G., Nicholas, Susanne B., O’Brien, Stephen J., Pahl, Madeleine V., Parekh, Rulan S., Pezzolesi, Marcus G., Rasooly, Rebekah S., Rotimi, Charles N., Rotter, Jerome I., Schelling, Jeffrey R., Seldin, Michael F., Shah, Vallabh O., Smiles, Adam M., Smith, Michael W., Taylor, Kent D., Thameem, Farook, Thornley-Brown, Denyse P., Truitt, Barbara J., Wanner, Christoph, Weil, E. Jennifer, Winkler, Cheryl A., Zager, Philip G., Igo, Robert P., Hanson, Robert L., Langefeld, Carl D.
Publicado 2015