Enhanced Permeability and Binding Activity of Isobutylene‐Grafted Peptides

por Sun, Shuang, Compañón, Ismael, Martínez‐Sáez, Nuria, Seixas, João D., Boutureira, Omar, Corzana, Francisco, Bernardes, Gonçalo J. L.
Publicado 2017

Structural basis for the synthesis of the core 1 structure by C1GalT1

por González-Ramírez, Andrés Manuel, Grosso, Ana Sofia, Yang, Zhang, Compañón, Ismael, Coelho, Helena, Narimatsu, Yoshiki, Clausen, Henrik, Marcelo, Filipa, Corzana, Francisco, Hurtado-Guerrero, Ramon
Publicado 2022

Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase

por Piniello, Beatriz, Macías-León, Javier, Miyazaki, Shun, García-García, Ana, Compañón, Ismael, Ghirardello, Mattia, Taleb, Víctor, Veloz, Billy, Corzana, Francisco, Miyagawa, Atsushi, Rovira, Carme, Hurtado-Guerrero, Ramon
Publicado 2023

Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut

por Taleb, Víctor, Liao, Qinghua, Narimatsu, Yoshiki, García-García, Ana, Compañón, Ismael, Borges, Rafael Junqueira, González-Ramírez, Andrés Manuel, Corzana, Francisco, Clausen, Henrik, Rovira, Carme, Hurtado-Guerrero, Ramon
Publicado 2022

Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo

por Martínez‐Sáez, Nuria, Sun, Shuang, Oldrini, Davide, Sormanni, Pietro, Boutureira, Omar, Carboni, Filippo, Compañón, Ismael, Deery, Michael J., Vendruscolo, Michele, Corzana, Francisco, Adamo, Roberto, Bernardes, Gonçalo J. L.
Publicado 2017

Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation

por Matos, Maria J., Navo, Claudio D., Hakala, Tuuli, Ferhati, Xhenti, Guerreiro, Ana, Hartmann, David, Bernardim, Barbara, Saar, Kadi L., Compañón, Ismael, Corzana, Francisco, Knowles, Tuomas P. J., Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo J. L.
Publicado 2019

The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

por de las Rivas, Matilde, Lira-Navarrete, Erandi, Daniel, Earnest James Paul, Compañón, Ismael, Coelho, Helena, Diniz, Ana, Jiménez-Barbero, Jesús, Peregrina, Jesús M., Clausen, Henrik, Corzana, Francisco, Marcelo, Filipa, Jiménez-Osés, Gonzalo, Gerken, Thomas A., Hurtado-Guerrero, Ramon
Publicado 2017

Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4

por de las Rivas, Matilde, Paul Daniel, Earnest James, Coelho, Helena, Lira-Navarrete, Erandi, Raich, Lluis, Compañón, Ismael, Diniz, Ana, Lagartera, Laura, Jiménez-Barbero, Jesús, Clausen, Henrik, Rovira, Carme, Marcelo, Filipa, Corzana, Francisco, Gerken, Thomas A., Hurtado-Guerrero, Ramon
Publicado 2018

Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation

por Lira-Navarrete, Erandi, de las Rivas, Matilde, Compañón, Ismael, Pallarés, María Carmen, Kong, Yun, Iglesias-Fernández, Javier, Bernardes, Gonçalo J. L., Peregrina, Jesús M., Rovira, Carme, Bernadó, Pau, Bruscolini, Pierpaolo, Clausen, Henrik, Lostao, Anabel, Corzana, Francisco, Hurtado-Guerrero, Ramon
Publicado 2015

Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody**

por Martínez-Sáez, Nuria, Castro-López, Jorge, Valero-González, Jessika, Madariaga, David, Compañón, Ismael, Somovilla, Víctor J, Salvadó, Míriam, Asensio, Juan L, Jiménez-Barbero, Jesús, Avenoza, Alberto, Busto, Jesús H, Bernardes, Gonçalo J L, Peregrina, Jesús M, Hurtado-Guerrero, Ramón, Corzana, Francisco
Publicado 2015

Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling

por Coelho, Helena, Rivas, Matilde de las, Grosso, Ana S., Diniz, Ana, Soares, Cátia O., Francisco, Rodrigo A., Dias, Jorge S., Compañon, Ismael, Sun, Lingbo, Narimatsu, Yoshiki, Vakhrushev, Sergey Y., Clausen, Henrik, Cabrita, Eurico J., Jiménez-Barbero, Jesús, Corzana, Francisco, Hurtado-Guerrero, Ramon, Marcelo, Filipa
Publicado 2022

Single Mutation on Trastuzumab Modulates the Stability of Antibody–Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

por Ferhati, Xhenti, Jiménez-Moreno, Ester, Hoyt, Emily A., Salluce, Giulia, Cabeza-Cabrerizo, Mar, Navo, Claudio D., Compañón, Ismael, Akkapeddi, Padma, Matos, Maria J., Salaverri, Noelia, Garrido, Pablo, Martínez, Alfredo, Laserna, Víctor, Murray, Thomas V., Jiménez-Osés, Gonzalo, Ravn, Peter, Bernardes, Gonçalo J. L., Corzana, Francisco
Publicado 2022