Glial cell reactivity and oxidative stress prevention in Alzheimer’s disease mice model by an optimized NMDA receptor antagonist

por Companys-Alemany, Júlia, Turcu, Andreea L., Vázquez, Santiago, Pallàs, Mercè, Griñán-Ferré, Christian
Publicado 2022

NMDA receptor antagonists reduce amyloid-β deposition by modulating calpain-1 signaling and autophagy, rescuing cognitive impairment in 5XFAD mice

por Companys-Alemany, Júlia, Turcu, Andreea L., Schneider, Marion, Müller, Christa E., Vázquez, Santiago, Griñán-Ferré, Christian, Pallàs, Mercè
Publicado 2022

Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline

por Cosín-Tomás, Marta, Álvarez-López, María Jesús, Companys-Alemany, Júlia, Kaliman, Perla, González-Castillo, Celia, Ortuño-Sahagún, Daniel, Pallàs, Mercè, Griñán-Ferré, Christian
Publicado 2018

Environmental Enrichment Modified Epigenetic Mechanisms in SAMP8 Mouse Hippocampus by Reducing Oxidative Stress and Inflammaging and Achieving Neuroprotection

por Griñan-Ferré, Christian, Puigoriol-Illamola, Dolors, Palomera-Ávalos, Verónica, Pérez-Cáceres, David, Companys-Alemany, Júlia, Camins, Antonio, Ortuño-Sahagún, Daniel, Rodrigo, M. Teresa, Pallàs, Mercè
Publicado 2016

Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease

por Griñán-Ferré, Christian, Companys-Alemany, Júlia, Jarné-Ferrer, Júlia, Codony, Sandra, González-Castillo, Celia, Ortuño-Sahagún, Daniel, Vilageliu, Lluïsa, Grinberg, Daniel, Vázquez, Santiago, Pallàs, Mercè
Publicado 2021

Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice

por Puigoriol-Illamola, Dolors, Companys-Alemany, Júlia, McGuire, Kris, Homer, Natalie Z. M., Leiva, Rosana, Vázquez, Santiago, Mole, Damian J., Griñán-Ferré, Christian, Pallàs, Mercè
Publicado 2021

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

por Companys-Alemany, Júlia, Turcu, Andreea L., Bellver-Sanchis, Aina, Loza, Maria I, Brea, José M., Canudas, Anna M, Leiva, Rosana, Vázquez, Santiago, Pallàs, Mercè, Griñán-Ferré, Christian
Publicado 2020

Cognitive Decline and BPSD Are Concomitant with Autophagic and Synaptic Deficits Associated with G9a Alterations in Aged SAMP8 Mice

por Vasilopoulou, Foteini, Bellver-Sanchis, Aina, Companys-Alemany, Júlia, Jarne-Ferrer, Júlia, Irisarri, Alba, Palomera-Ávalos, Verónica, Gonzalez-Castillo, Celia, Ortuño-Sahagún, Daniel, Sanfeliu, Coral, Pallàs, Mercè, Griñán-Ferré, Christian
Publicado 2022

Structure‐Based Virtual Screening and in vitro and in vivo Analyses Revealed Potent Methyltransferase G9a Inhibitors as Prospective Anti‐Alzheimer's Agents

por Bellver‐Sanchis, Aina, Singh Choudhary, Bhanwar, Companys‐Alemany, Júlia, Sukanya, Ávila‐López, Pedro A., Martínez Rodríguez, Antón Leandro, Brea Floriani, Jose Manuel, Malik, Ruchi, Pallàs, Mercè, Pérez, Belén, Griñán‐Ferré, Christian
Publicado 2022