Up-regulation of GABA(B) Receptor Signaling by Constitutive Assembly with the K(+) Channel Tetramerization Domain-containing Protein 12 (KCTD12)

por Ivankova, Klara, Turecek, Rostislav, Fritzius, Thorsten, Seddik, Riad, Prezeau, Laurent, Comps-Agrar, Laëtitia, Pin, Jean-Philippe, Fakler, Bernd, Besseyrias, Valerie, Gassmann, Martin, Bettler, Bernhard
Publicado 2013

Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action

por Chan, Jocelyn, Chan, Joyce, Shao, Lily, Stawicki, Scott S., Pham, Victoria C., Akita, Rob W., Hafner, Marc, Crocker, Lisa, Yu, Kebing, Koerber, James T., Schaefer, Gabriele, Comps-Agrar, Laetitia
Publicado 2022

CRF RECEPTOR1 REGULATES ANXIETY BEHAVIOUR VIA SENSITIZATION OF 5-HT2 RECEPTOR SIGNALING

por Magalhaes, Ana C., Holmes, Kevin D., Dale, Lianne B., Comps-Agrar, Laetitia, Lee, Dennis, Yadav, Prem N., Drysdale, Linsay, Poulter, Micheal O., Roth, Bryan L., Pin, Jean-Philippe, Anisman, Hymie, Ferguson, Stephen S. G.
Publicado 2010

Structural basis for HCMV Pentamer receptor recognition and antibody neutralization

por Kschonsak, Marc, Johnson, Matthew C., Schelling, Rachel, Green, Evan M., Rougé, Lionel, Ho, Hoangdung, Patel, Nidhi, Kilic, Cem, Kraft, Edward, Arthur, Christopher P., Rohou, Alexis L., Comps-Agrar, Laetitia, Martinez-Martin, Nadia, Perez, Laurent, Payandeh, Jian, Ciferri, Claudio
Publicado 2022

Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8(+) T cell responses

por Banta, Karl L., Xu, Xiaozheng, Chitre, Avantika S., Au-Yeung, Amelia, Takahashi, Chikara, O’Gorman, William E., Wu, Thomas D., Mittman, Stephanie, Cubas, Rafael, Comps-Agrar, Laetitia, Fulzele, Amit, Bennett, Eric J., Grogan, Jane L., Hui, Enfu, Chiang, Eugene Y., Mellman, Ira
Publicado 2022

Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development

por Mai, Elaine, Chan, Joyce, Goon, Levina, Ego, Braeden K., Bevers, Jack, Wong, Tiffany, Wong, Manda, Corpuz, Racquel, Xi, Hongkang, Wu, Jia, Schneider, Kellen, Seshasayee, Dhaya, Grimbaldeston, Michele, Nakamura, Gerald, Indjeian, Vahan B., van Lookeren Campagne, Menno, Loyet, Kelly M., Comps-Agrar, Laetitia
Publicado 2021

Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8

por Sun, Dawei, Sun, Yonglian, Janezic, Eric, Zhou, Tricia, Johnson, Matthew, Azumaya, Caleigh, Noreng, Sigrid, Chiu, Cecilia, Seki, Akiko, Arenzana, Teresita L., Nicoludis, John M., Shi, Yongchang, Wang, Baomei, Ho, Hoangdung, Joshi, Prajakta, Tam, Christine, Payandeh, Jian, Comps-Agrar, Laëtitia, Wang, Jianyong, Rutz, Sascha, Koerber, James T., Masureel, Matthieu
Publicado 2023

Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD

por Storek, Kelly M, Chan, Joyce, Vij, Rajesh, Chiang, Nancy, Lin, Zhonghua, Bevers, Jack, Koth, Christopher M, Vernes, Jean-Michel, Meng, Y Gloria, Yin, JianPing, Wallweber, Heidi, Dalmas, Olivier, Shriver, Stephanie, Tam, Christine, Schneider, Kellen, Seshasayee, Dhaya, Nakamura, Gerald, Smith, Peter A, Payandeh, Jian, Koerber, James T, Comps-Agrar, Laetitia, Rutherford, Steven T
Publicado 2019

A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies

por Vij, Rajesh, Lin, Zhonghua, Chiang, Nancy, Vernes, Jean-Michel, Storek, Kelly M., Park, Summer, Chan, Joyce, Meng, Y. Gloria, Comps-Agrar, Laetitia, Luan, Peng, Lee, Sophia, Schneider, Kellen, Bevers, Jack, Zilberleyb, Inna, Tam, Christine, Koth, Christopher M., Xu, Min, Gill, Avinash, Auerbach, Marcy R., Smith, Peter A., Rutherford, Steven T., Nakamura, Gerald, Seshasayee, Dhaya, Payandeh, Jian, Koerber, James T.
Publicado 2018

Antibody targeting of E3 ubiquitin ligases for receptor degradation

por Marei, Hadir, Tsai, Wen-Ting K., Kee, Yee-Seir, Ruiz, Karen, He, Jieyan, Cox, Chris, Sun, Tao, Penikalapati, Sai, Dwivedi, Pankaj, Choi, Meena, Kan, David, Saenz-Lopez, Pablo, Dorighi, Kristel, Zhang, Pamela, Kschonsak, Yvonne T., Kljavin, Noelyn, Amin, Dhara, Kim, Ingrid, Mancini, Andrew G., Nguyen, Thao, Wang, Chunling, Janezic, Eric, Doan, Alexander, Mai, Elaine, Xi, Hongkang, Gu, Chen, Heinlein, Melanie, Biehs, Brian, Wu, Jia, Lehoux, Isabelle, Harris, Seth, Comps-Agrar, Laetitia, Seshasayee, Dhaya, de Sauvage, Frederic J., Grimmer, Matthew, Li, Jing, Agard, Nicholas J., de Sousa e Melo, Felipe
Publicado 2022

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

por Kolumam, Ganesh, Chen, Mark Z., Tong, Raymond, Zavala-Solorio, Jose, Kates, Lance, van Bruggen, Nicholas, Ross, Jed, Wyatt, Shelby K., Gandham, Vineela D., Carano, Richard A.D., Dunshee, Diana Ronai, Wu, Ai-Luen, Haley, Benjamin, Anderson, Keith, Warming, Søren, Rairdan, Xin Y., Lewin-Koh, Nicholas, Zhang, Yingnan, Gutierrez, Johnny, Baruch, Amos, Gelzleichter, Thomas R., Stevens, Dale, Rajan, Sharmila, Bainbridge, Travis W., Vernes, Jean-Michel, Meng, Y. Gloria, Ziai, James, Soriano, Robert H., Brauer, Matthew J., Chen, Yongmei, Stawicki, Scott, Kim, Hok Seon, Comps-Agrar, Laëtitia, Luis, Elizabeth, Spiess, Christoph, Wu, Yan, Ernst, James A., McGuinness, Owen P., Peterson, Andrew S., Sonoda, Junichiro
Publicado 2015