Rare Monogenic Diseases: Molecular Pathophysiology and Novel Therapies

por Condò, Ivano
Publicado 2022

Drug Repositioning in Friedreich Ataxia

por Rufini, Alessandra, Malisan, Florence, Condò, Ivano, Testi, Roberto
Publicado 2022

Interferon Gamma Enhances Cytoprotective Pathways via Nrf2 and MnSOD Induction in Friedreich’s Ataxia Cells

por Luffarelli, Riccardo, Panarello, Luca, Quatrana, Andrea, Tiano, Francesca, Fortuni, Silvia, Rufini, Alessandra, Malisan, Florence, Testi, Roberto, Condò, Ivano
Publicado 2023

Acetylation Suppresses the Proapoptotic Activity of GD3 Ganglioside

por Malisan, Florence, Franchi, Luigi, Tomassini, Barbara, Ventura, Natascia, Condò, Ivano, Rippo, Maria Rita, Rufini, Alessandra, Liberati, Laura, Nachtigall, Claudia, Kniep, Bernhard, Testi, Roberto
Publicado 2002

Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model

por Tomassini, Barbara, Arcuri, Gaetano, Fortuni, Silvia, Sandi, Chiranjeevi, Ezzatizadeh, Vahid, Casali, Carlo, Condò, Ivano, Malisan, Florence, Al-Mahdawi, Sahar, Pook, Mark, Testi, Roberto
Publicado 2012

E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia

por Benini, Monica, Fortuni, Silvia, Condò, Ivano, Alfedi, Giulia, Malisan, Florence, Toschi, Nicola, Serio, Dario, Massaro, Damiano Sergio, Arcuri, Gaetano, Testi, Roberto, Rufini, Alessandra
Publicado 2017

Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells

por Rufini, Alessandra, Cavallo, Francesca, Condò, Ivano, Fortuni, Silvia, De Martino, Gabriella, Incani, Ottaviano, Di Venere, Almerinda, Benini, Monica, Massaro, Damiano Sergio, Arcuri, Gaetano, Serio, Dario, Malisan, Florence, Testi, Roberto
Publicado 2015

Sensitivity of Neuroimaging Indicators in Monitoring the Effects of Interferon Gamma Treatment in Friedreich’s Ataxia

por Vavla, Marinela, Arrigoni, Filippo, Toschi, Nicola, Peruzzo, Denis, D’Angelo, Maria Grazia, Gandossini, Sandra, Russo, Annamaria, Diella, Eleonora, Tirelli, Stefania, Salati, Roberto, Rufini, Alessandra, Condo, Ivano, Testi, Roberto, Martinuzzi, Andrea
Publicado 2020

SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia

por Bon, Carlotta, Luffarelli, Riccardo, Russo, Roberta, Fortuni, Silvia, Pierattini, Bianca, Santulli, Chiara, Fimiani, Cristina, Persichetti, Francesca, Cotella, Diego, Mallamaci, Antonello, Santoro, Claudio, Carninci, Piero, Espinoza, Stefano, Testi, Roberto, Zucchelli, Silvia, Condò, Ivano, Gustincich, Stefano
Publicado 2019

Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans

por Schiavi, Alfonso, Torgovnick, Alessandro, Kell, Alison, Megalou, Evgenia, Castelein, Natascha, Guccini, Ilaria, Marzocchella, Laura, Gelino, Sara, Hansen, Malene, Malisan, Florence, Condò, Ivano, Bei, Roberto, Rea, Shane L., Braeckman, Bart P., Tavernarakis, Nektarios, Testi, Roberto, Ventura, Natascia
Publicado 2013

Corrigendum to “Autophagy induction extends lifespan and reduces lipids content in response to frataxin silencing in C. elegans” [Exp. Gerontol. 48 (2013) 191–201]

por Schiavi, Alfonso, Torgovnick, Alessandro, Kell, Alison, Megalou, Evgenia, Castelein, Natascha, Guccini, Ilaria, Marzocchella, Laura, Gelino, Sara, Hansen, Malene, Malisan, Florence, Condò, Ivano, Bei, Roberto, Rea, Shane L., Braeckman, Bart P., Tavernarakis, Nektarios, Testi, Roberto, Ventura, Natascia
Publicado 2013