Structural analysis of the dual agonism at GLP-1R and GCGR

por Li, Yang, Zhou, Qingtong, Dai, Antao, Zhao, Fenghui, Chang, Rulue, Ying, Tianlei, Wu, Beili, Yang, Dehua, Wang, Ming-Wei, Cong, Zhaotong
Publicado 2023

GPR160 is a potential biomarker associated with prostate cancer

por Guo, Wanjing, Zhang, Junyu, Zhou, Yan, Zhou, Caihong, Yang, Yunjie, Cong, Zhaotong, Dong, Jibin, Yang, Dehua, Dai, Bo, Wang, Ming-Wei
Publicado 2021

Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors

por Feng, Wenbo, Zhou, Qingtong, Chen, Xianyue, Dai, Antao, Cai, Xiaoqing, Liu, Xiao, Zhao, Fenghui, Chen, Yan, Ye, Chenyu, Xu, Yingna, Cong, Zhaotong, Li, Hao, Lin, Shi, Yang, Dehua, Wang, Ming-Wei
Publicado 2023

Structural basis of peptidomimetic agonism revealed by small-molecule GLP-1R agonists Boc5 and WB4-24

por Cong, Zhaotong, Zhou, Qingtong, Li, Yang, Chen, Li-Nan, Zhang, Zi-Chen, Liang, Anyi, Liu, Qing, Wu, Xiaoyan, Dai, Antao, Xia, Tian, Wu, Wei, Zhang, Yan, Yang, Dehua, Wang, Ming-Wei
Publicado 2022

Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2

por Wang, Xi, Cheng, Xi, Zhao, Lihua, Wang, Yuzhe, Ye, Chenyu, Zou, Xinyu, Dai, Antao, Cong, Zhaotong, Chen, Jian, Zhou, Qingtong, Xia, Tian, Jiang, Hualiang, Xu, H. Eric, Yang, Dehua, Wang, Ming-Wei
Publicado 2021

Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor

por Cong, Zhaotong, Chen, Li-Nan, Ma, Honglei, Zhou, Qingtong, Zou, Xinyu, Ye, Chenyu, Dai, Antao, Liu, Qing, Huang, Wei, Sun, Xianqiang, Wang, Xi, Xu, Peiyu, Zhao, Lihua, Xia, Tian, Zhong, Wenge, Yang, Dehua, Eric Xu, H., Zhang, Yan, Wang, Ming-Wei
Publicado 2021

Constitutive signal bias mediated by the human GHRHR splice variant 1

por Cong, Zhaotong, Zhou, Fulai, Zhang, Chao, Zou, Xinyu, Zhang, Huibing, Wang, Yuzhe, Zhou, Qingtong, Cai, Xiaoqing, Liu, Qiaofeng, Li, Jie, Shao, Lijun, Mao, Chunyou, Wang, Xi, Wu, Jihong, Xia, Tian, Zhao, Li-Hua, Jiang, Hualiang, Zhang, Yan, Xu, H. Eric, Cheng, Xi, Yang, Dehua, Wang, Ming-Wei
Publicado 2021

Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors

por Zhao, Fenghui, Zhou, Qingtong, Cong, Zhaotong, Hang, Kaini, Zou, Xinyu, Zhang, Chao, Chen, Yan, Dai, Antao, Liang, Anyi, Ming, Qianqian, Wang, Mu, Chen, Li-Nan, Xu, Peiyu, Chang, Rulve, Feng, Wenbo, Xia, Tian, Zhang, Yan, Wu, Beili, Yang, Dehua, Zhao, Lihua, Xu, H. Eric, Wang, Ming-Wei
Publicado 2022

Structural basis for activation of the growth hormone-releasing hormone receptor

por Zhou, Fulai, Zhang, Huibing, Cong, Zhaotong, Zhao, Li-Hua, Zhou, Qingtong, Mao, Chunyou, Cheng, Xi, Shen, Dan-Dan, Cai, Xiaoqing, Ma, Cheng, Wang, Yuzhe, Dai, Antao, Zhou, Yan, Sun, Wen, Zhao, Fenghui, Zhao, Suwen, Jiang, Hualiang, Jiang, Yi, Yang, Dehua, Eric Xu, H., Zhang, Yan, Wang, Ming-Wei
Publicado 2020

A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor

por Sun, Wen, Chen, Li-Nan, Zhou, Qingtong, Zhao, Li-Hua, Yang, Dehua, Zhang, Huibing, Cong, Zhaotong, Shen, Dan-Dan, Zhao, Fenghui, Zhou, Fulai, Cai, Xiaoqing, Chen, Yan, Zhou, Yan, Gadgaard, Sarina, van der Velden, Wijnand J. C., Zhao, Suwen, Jiang, Yi, Rosenkilde, Mette M., Xu, H. Eric, Zhang, Yan, Wang, Ming-Wei
Publicado 2020